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Protein

Protein FAM74A4/A6

Gene

FAM74A4

more
Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciZFISH:G66-31666-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM74A4/A6
Gene namesi
Name:FAM74A4
AND
Name:FAM74A6
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:32032. FAM74A4.
HGNC:34036. FAM74A6.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002660471 – 123Protein FAM74A4/A6Add BLAST123

Proteomic databases

PRIDEiQ5TZK3.

PTM databases

iPTMnetiQ5TZK3.
PhosphoSitePlusiQ5TZK3.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
CCDC85BQ158343EBI-10247271,EBI-739674
CCNDBP1O952735EBI-10247271,EBI-748961
CEP44Q9C0F13EBI-10247271,EBI-744115
EFEMP2O959675EBI-10247271,EBI-743414
EMG1Q929795EBI-10247271,EBI-718638
HMBOX1Q6NT763EBI-10247271,EBI-2549423
IKZF1Q134223EBI-10247271,EBI-745305
KRT31Q153233EBI-10247271,EBI-948001
KRT40Q6A1623EBI-10247271,EBI-10171697
KRTAP10-5P603703EBI-10247271,EBI-10172150
KRTAP10-7P604093EBI-10247271,EBI-10172290
KRTAP10-8P604105EBI-10247271,EBI-10171774
KRTAP10-9P604113EBI-10247271,EBI-10172052
KRTAP4-2Q9BYR53EBI-10247271,EBI-10172511
KRTAP5-9P263715EBI-10247271,EBI-3958099
LZTS2Q9BRK43EBI-10247271,EBI-741037
MEOX2A4D1275EBI-10247271,EBI-10172134
MTUS2Q5JR593EBI-10247271,EBI-742948
NOTCH2NLQ7Z3S95EBI-10247271,EBI-945833
PDE4DIPQ5VU433EBI-10247271,EBI-1105124
PHC2Q8IXK03EBI-10247271,EBI-713786
RPGRIP1Q96KN73EBI-10247271,EBI-1050213
STX11O755583EBI-10247271,EBI-714135
TCF4P158843EBI-10247271,EBI-533224

Protein-protein interaction databases

IntActiQ5TZK3. 28 interactors.

Structurei

3D structure databases

ProteinModelPortaliQ5TZK3.
SMRiQ5TZK3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FAM74 family.Curated

Phylogenomic databases

InParanoidiQ5TZK3.
PhylomeDBiQ5TZK3.

Sequencei

Sequence statusi: Complete.

Q5TZK3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWRELRGCPG GDVETAQRLS QRRRGKSSEA VPEKTWRAQR MSQRRRGESS
60 70 80 90 100
EAVPEKTWKE LRNSETVPEK TWKQLRGCLQ EDVQRVQRLS RRRHGESSKA
110 120
VHKKMWREFR GCRYCCTWLF FFG
Length:123
Mass (Da):14,773
Last modified:July 5, 2005 - v1
Checksum:i1DAC8479980565FF
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti13V → L in BAC86850 (PubMed:14702039).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK127145 mRNA. Translation: BAC86850.1.
AL445584 Genomic DNA. No translation available.
BX005040 Genomic DNA. No translation available.
UniGeneiHs.741141.
Hs.742601.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK127145 mRNA. Translation: BAC86850.1.
AL445584 Genomic DNA. No translation available.
BX005040 Genomic DNA. No translation available.
UniGeneiHs.741141.
Hs.742601.

3D structure databases

ProteinModelPortaliQ5TZK3.
SMRiQ5TZK3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ5TZK3. 28 interactors.

PTM databases

iPTMnetiQ5TZK3.
PhosphoSitePlusiQ5TZK3.

Proteomic databases

PRIDEiQ5TZK3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

GeneCardsiFAM74A4.
FAM74A6.
HGNCiHGNC:32032. FAM74A4.
HGNC:34036. FAM74A6.
neXtProtiNX_Q5TZK3.
GenAtlasiSearch...

Phylogenomic databases

InParanoidiQ5TZK3.
PhylomeDBiQ5TZK3.

Enzyme and pathway databases

BioCyciZFISH:G66-31666-MONOMER.

Miscellaneous databases

PROiQ5TZK3.

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiFAM74_HUMAN
AccessioniPrimary (citable) accession number: Q5TZK3
Secondary accession number(s): A6NH89, Q6ZSU6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: July 5, 2005
Last modified: November 30, 2016
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.