CDC42-binding protein kinase beta (DMPK-like)

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. the chemical reaction it catalyzes. This information usually correlates with the presence of an EC (Enzyme Commission) number in the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• ATP binding Source: UniProtKB-KW
• metal ion binding Source: UniProtKB-KW
• protein serine/threonine kinase activity Source: UniProtKB-KW

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processⁱ

• actin cytoskeleton organization Source: InterPro
• cell migration Source: InterPro
• intracellular signal transduction Source: InterPro

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsⁱ

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressionⁱ

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Domains and Repeats

Coiled coil

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesⁱ

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MSAKVRLKKL EQLLLDGHQK NDKSLSVETL LDILICLYNE CSNSPLKREK 
        60         70         80         90        100
HVTDFLEWVK PFTTTVKEMR LHRDDFEMLK VIGRGAFGEV AVVKMKHTER 
       110        120        130        140        150
VYAMKILNKW EMLKRAETAC FREERNVLVN GDCQWITTLH YAFQDDNYLY 
       160        170        180        190        200
LVMDYYVGGD LLTLLSKFED RLPEDMAKFY VAEMVLAIHS IHQQRYVHRD 
       210        220        230        240        250
IKPDNVLLDM NGHIRLADFG SCLKMMQDGT VQSSVAVGTP DYISPEILQA 
       260        270        280        290        300
MEDGMGKYGP ECDWWSLGVC MYEMLYGETP FYAESLVETY GKIMNHEERF 
       310        320        330        340        350
QFPSHITDVS EDAKDLIQRL ICSRERRLGQ HGIEEFRKHA FFSGIDWENI 
       360        370        380        390        400
RNMEAPYIPD VSSPSDTSNF DVDDDVLKNP DIAPPVSHTG FTGQHLPFVG 
       410        420        430        440        450
FTYTTESCFS DGGSMRGVAL SDGGTGEDLQ DGGMQVEAFE KRIRCLEQEK 
       460        470        480        490        500
LELNRKLQES TQAVQSLHGS GRGAGTLGRD KEIKKLNEEI DRLKKKLADS 
       510        520        530        540        550
DRLEHQLEEA VTLRQDFESS STKLKALDKQ VKALKLEKED IHKQLVESLD 
       560        570        580        590        600
RLKSQTKELK DAHQQRKLAM QEFSEVNERM AELRSQKQRL SRQLRDKEEE 
       610        620        630        640        650
MEVVMQKIDA MRQDIRKTEK ARKELESQLE DARAEASKER KLREHSEVYS 
       660        670        680        690        700
KQLESELETL KVKQGAGRAS GLGAETQQEL TKLKSELDKK GLYYEEELVR 
       710        720        730        740        750
REASHTTEMK NLRKELQDSE GQQLSLHKEL LALKEKLEKA KRERQIEMEE 
       760        770        780        790        800
AINALKEQYE RERNLMSEDN RKLTAETDRL CSFVDKLTAQ NRQLEDELQE 
       810        820        830        840        850
LASKKESVAH WEAQIAEIIQ WVSDEKDARG YLQALASKMT EELESLRSSS 
       860        870        880        890        900
LGSRTLDPLW KVRRSQKLDM SARLELQSAL EAEIRAKQLV HDELRKVKAA 
       910        920        930        940        950
NISFESKLKD TEAKNRELEE QLENMKKEME ESRSRSDKGL KLPDFQDSIF 
       960        970        980        990       1000
DYFNTSPLAH ELTFRTSSVG DVDVAPQKTD IPPSSPSAAT EQDEAVKPQA 
      1010       1020       1030       1040       1050
TTPATPSPMY QPTLTAPKPK AHQLSIKTFS SPTQCTHCTS LMVGQMRQGY 
      1060       1070       1080       1090       1100
ACEVCSFICH VSCKDNAPQL CPIPPEQTKR PLGIDVQRGI GTAYKGFVRI 
      1110       1120       1130       1140       1150
PKPTGVKKGW QRAYAVVCDC KLFLYEVPEG KSTQPVVMAS QVLDLRDEEF 
      1160       1170       1180       1190       1200
SVSSVLASDV IHANHKDVPC IFRVTSSALK SSIRPVPLLI LAESEAEKRK 
      1210       1220       1230       1240       1250
WVGILEGLQS ILAKNRLKNR VVHVLHEAYD SSLPAIKTTL SAAIVDRERI 
      1260       1270       1280       1290       1300
VLGTEDGLFV VEITRDVIVR AADCKKVCQI ELIPKEKMVA LLSGRNRHVH 
      1310       1320       1330       1340       1350
LYPWAALEGA EGGFDAKLTD TRGCQAMTIG NLRPGGPACL FAGVKRQVFC 
      1360       1370       1380       1390       1400
YEITRAKPHH RKLWEVQAPG VVQWLGIIRE RICVGYPSGF ALLAMQGESS 
      1410       1420       1430       1440       1450
PVSLVSPGDP SLAFLAQQPL DALHAMEVGS NELLLCFSQL GVYVDATGRR 
      1460       1470       1480       1490       1500
SRTQELMWPS TPLACSSNSN CLTVYSDYGV DVFDVHTMEW VQTISLRKIR 
      1510       1520       1530       1540       1550
PLNVEGSLNL LSIEQPHLIY FSNNSSDGCD LAIPETSDNS KKLMVRTRSK 
      1560       1570       1580       1590       1600
RKFLFKVPEE ERLQQRREML RDPEMRSKLI SHPTNFNHVA HMGPGDGMQV 
      1610       1620       1630       1640       1650
LMDLPLSVMP SSQDDLSKDK PRPLSSISRQ QRSKTHITRT ASGGGDFGGA 
      1660       1670       1680       1690       1700
GSSRSISDQD QDYEREPDSD STKHSTPSNS SNPSSPPSPN SPHRSQLTLD 

SLDQSLDG                                               

Sequence databases

Genome annotation databases

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 50% Identity

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termⁱ