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Protein
Submitted name:

AGAP012069-PA

Gene

3291503

Organism
Anopheles gambiae (African malaria mosquito)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei119PROSITE-ProRule annotation1
Active sitei277PROSITE-ProRule annotation1
Active sitei311PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protease, Thiol proteasePROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
AGAP012069-PAImported
Submitted name:
Calpain-3 isoform bImported
Gene namesi
Name:3291503Imported
ORF Names:AgaP_AGAP012069Imported
OrganismiAnopheles gambiae (African malaria mosquito)Imported
Taxonomic identifieri7165 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraNematoceraCulicoideaCulicidaeAnophelinaeAnopheles
Proteomesi
  • UP000007062 Componenti: Chromosome 3L

Subcellular locationi

Interactioni

Protein-protein interaction databases

STRINGi7165.AGAP012069-PA

Structurei

3D structure databases

ProteinModelPortaliQ5TMZ6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini61 – 369Calpain catalyticInterPro annotationAdd BLAST309

Sequence similaritiesi

Belongs to the peptidase C2 family.SAAS annotation

Phylogenomic databases

eggNOGiKOG0045 Eukaryota
ENOG410XP0B LUCA
HOGENOMiHOG000232036
InParanoidiQ5TMZ6
OMAiCKSMVVL
OrthoDBiEOG091G04E4
PhylomeDBiQ5TMZ6

Family and domain databases

CDDicd00044 CysPc, 1 hit
InterProiView protein in InterPro
IPR022684 Calpain_cysteine_protease
IPR022682 Calpain_domain_III
IPR022683 Calpain_III
IPR036213 Calpain_III_sf
IPR000169 Pept_cys_AS
IPR001300 Peptidase_C2_calpain_cat
PfamiView protein in Pfam
PF01067 Calpain_III, 1 hit
PF00648 Peptidase_C2, 1 hit
PRINTSiPR00704 CALPAIN
SMARTiView protein in SMART
SM00720 calpain_III, 1 hit
SM00230 CysPc, 1 hit
SUPFAMiSSF49758 SSF49758, 1 hit
PROSITEiView protein in PROSITE
PS50203 CALPAIN_CAT, 1 hit
PS00139 THIOL_PROTEASE_CYS, 1 hit

Sequencei

Sequence statusi: Complete.

Q5TMZ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHFISWWLGS AEDGSDHDRS SSSIASESDC RSNTDLDAFE NQPTVKDFQA
60 70 80 90 100
LRDRCLAEGT LFEDPEFPAN NFSIYHSNPP KKGEREFEWK RPGEIVPSPK
110 120 130 140 150
FVTEGFSRFD VRQGIIGNCW FISSCSALTS HQELFERVVP LDNGQFEADH
160 170 180 190 200
YAGLFHFRFW QYGQWVEVIV DDRLPVGKNN QLLFISSSEK DEFWGALLEK
210 220 230 240 250
AYAKLHGSYE ALDSGTGREG MVDLTGGITE FYQLKGNEPD DLFERLESNL
260 270 280 290 300
ARRSLITAGI NGNERERVQS VNLVPQHEYS VTKVTRLDAT LHMLDFGAGN
310 320 330 340 350
AVDVRLICVR NPWGRGEWSG AWGDHSLEWI MVRDEKMEEL NIVKEDGEFW
360 370 380 390 400
MNFEDFVHHF DDVSVCYQCP GDMGKELRAR YPREMVSEMG EWKRSATAGG
410 420 430 440 450
SDENSFWSNP QYVLKLAHHE GYEADSRISV TIGLMQKHHR AKGTSFLSLR
460 470 480 490 500
LLVFPIPNHV LTGNRFLPKS FFDNVIPVET EANFETTREV VGRYKLPPGR
510 520 530
YVVVPHTWKP QQEAEFMLRI FAEGSVTKLC YCAGDVIG
Length:538
Mass (Da):61,418
Last modified:January 9, 2007 - v2
Checksum:i8C7328F04B31AFD2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAAB01008986 Genomic DNA Translation: EAL38766.2
RefSeqiXP_552135.2, XM_552135.2

Genome annotation databases

EnsemblMetazoaiAGAP012069-RA; AGAP012069-PA; AGAP012069
GeneIDi3291503
KEGGiaga:AgaP_AGAP012069
VectorBaseiAGAP012069-RA; AGAP012069-PA; AGAP012069

Similar proteinsi

Entry informationi

Entry nameiQ5TMZ6_ANOGA
AccessioniPrimary (citable) accession number: Q5TMZ6
Entry historyiIntegrated into UniProtKB/TrEMBL: December 7, 2004
Last sequence update: January 9, 2007
Last modified: May 23, 2018
This is version 92 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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