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Q5TLG6 (Q5TLG6_9CNID) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:Dronpa EMBL BAD72874.1
OrganismEchinophyllia sp. SC22 EMBL BAD72874.1
Taxonomic identifier301887 [NCBI]
Taxonomic lineageEukaryotaMetazoaCnidariaAnthozoaHexacoralliaScleractiniaFaviinaLobophylliidaeEchinophyllia

Protein attributes

Sequence length224 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding1341Potassium; via carbonyl oxygen PDB 4IZN
Metal binding1361Potassium; via carbonyl oxygen PDB 4IZN
Metal binding1641Potassium PDB 4IZN

Sequences

Sequence LengthMass (Da)Tools
Q5TLG6 [UniParc].

Last modified December 21, 2004. Version 1.
Checksum: 9091A477C9A99D98

FASTA22425,481
        10         20         30         40         50         60 
MSVIKPDMKI KLRMEGAVNG HPFAIEGVGL GKPFEGKQSM DLKVKEGGPL PFAYDILTTV 

        70         80         90        100        110        120 
FCYGNRVFAK YPENIVDYFK QSFPEGYSWE RSMNYEDGGI CNATNDITLD GDCYIYEIRF 

       130        140        150        160        170        180 
DGVNFPANGP VMQKRTVKWE PSTEKLYVRD GVLKGDVNMA LSLEGGGHYR CDFKTTYKAK 

       190        200        210        220 
KVVQLPDYHF VDHHIEIKSH DKDYSNVNLH EHAEAHSELP RQAK 

« Hide

References

[1]"Regulated fast nucleocytoplasmic shuttling observed by reversible protein highlighting."
Ando R., Mizuno H., Miyawaki A.
Science 306:1370-1373(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: SC22 EMBL BAD72874.1.
[2]"The 1.7 A crystal structure of Dronpa: a photoswitchable green fluorescent protein."
Wilmann P.G., Turcic K., Battad J.M., Wilce M.C., Devenish R.J., Prescott M., Rossjohn J.
J. Mol. Biol. 364:213-224(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS).
[3]"Structural characterization of the photoswitchable fluorescent protein Dronpa-C62S."
Nam K.H., Kwon O.Y., Sugiyama K., Lee W.H., Kim Y.K., Song H.K., Kim E.E., Park S.Y., Jeon H., Hwang K.Y.
Biochem. Biophys. Res. Commun. 354:962-967(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS) OF 2-224.
[4]"1.8 A bright-state structure of the reversibly switchable fluorescent protein Dronpa guides the generation of fast switching variants."
Stiel A.C., Trowitzsch S., Weber G., Andresen M., Eggeling C., Hell S.W., Jakobs S., Wahl M.C.
Biochem. J. 402:35-42(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS).
[5]"Structural basis for reversible photoswitching in Dronpa."
Andresen M., Stiel A.C., Trowitzsch S., Weber G., Eggeling C., Wahl M.C., Hell S.W., Jakobs S.
Proc. Natl. Acad. Sci. U.S.A. 104:13005-13009(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.95 ANGSTROMS).
[6]"Light-dependent regulation of structural flexibility in a photochromic fluorescent protein."
Mizuno H., Mal T.K., Walchli M., Kikuchi A., Fukano T., Ando R., Jeyakanthan J., Taka J., Shiro Y., Ikura M., Miyawaki A.
Proc. Natl. Acad. Sci. U.S.A. 105:9227-9232(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.75 ANGSTROMS).
[7]"Low-temperature chromophore isomerization reveals the photoswitching mechanism of the fluorescent protein Padron."
Faro A.R., Carpentier P., Jonasson G., Pompidor G., Arcizet D., Demachy I., Bourgeois D.
J. Am. Chem. Soc. 133:16362-16365(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.20 ANGSTROMS) OF 142-218; 2-93 AND 95-140.
[8]"Structural basis for the influence of a single mutation K145N on the oligomerization and photoswitching rate of Dronpa."
Nguyen Bich N., Moeyaert B., Van Hecke K., Dedecker P., Mizuno H., Hofkens J., Van Meervelt L.
Acta Crystallogr. D 68:1653-1659(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.95 ANGSTROMS).
[9]"Green-to-red photoconvertible Dronpa mutant for multimodal super-resolution fluorescence microscopy."
Moeyaert B., Nguyen Bich N., De Zitter E., Rocha S., Clays K., Mizuno H., van Meervelt L., Hofkens J., Dedecker P.
ACS Nano 8:1664-1673(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.95 ANGSTROMS) OF 1-101 AND 103-224 IN COMPLEX WITH POTASSIUM.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB180726 Genomic DNA. Translation: BAD72874.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2GX0X-ray1.90A/B/C/D2-224[»]
2GX2X-ray1.80A/B/C/D/E/F/G/H/I/J/K/L2-224[»]
2IE2X-ray1.70A/B/C/D/E/F1-224[»]
2IOVX-ray1.80A/B/C/D1-224[»]
2POXX-ray1.95A/B/C/D1-224[»]
2Z1OX-ray1.75A/B/C/D1-224[»]
2Z6XX-ray2.30A/B/C/D/E/F/G/H1-224[»]
2Z6YX-ray2.00A/B/C/D1-224[»]
2Z6ZX-ray1.80A/B/C/D/E/F1-224[»]
3ZUFX-ray2.20A/B/C/D/E/F142-218[»]
A/B/C/D/E/F2-93[»]
A/B/C/D/E/F95-140[»]
3ZUJX-ray2.34A/B/C/D/E/F142-217[»]
A/B/C/D/E/F2-93[»]
A/B/C/D/E/F95-140[»]
3ZULX-ray2.30A/B/C/D/E/F142-224[»]
A/B/C/D/E/F2-93[»]
A/B/C/D/E/F95-140[»]
4EMQX-ray1.95A/B/C/D/E/F1-224[»]
4HQ8X-ray1.95A/B/C/D/E/F1-101[»]
A/B/C/D/E/F103-224[»]
4HQ9X-ray2.07A/B/C/D/E/F1-101[»]
A/B/C/D/E/F103-224[»]
4HQCX-ray2.05A/B/C/D/E/F1-101[»]
A/B/C/D/E/F103-224[»]
4IZNX-ray2.15A/B/C/D/E/F/G/H/I/J/K/L1-101[»]
A/B/C/D/E/F/G/H/I/J/K/L103-224[»]
ProteinModelPortalQ5TLG6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

DIPDIP-46137N.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D2.40.155.10. 1 hit.
InterProIPR009017. GFP.
IPR011584. GFP-related.
IPR023413. GFP_like.
IPR000786. Green_fluorescent_prot.
[Graphical view]
PfamPF01353. GFP. 1 hit.
[Graphical view]
PRINTSPR01229. GFLUORESCENT.
SUPFAMSSF54511. SSF54511. 1 hit.
ProtoNetSearch...

Other

EvolutionaryTraceQ5TLG6.

Entry information

Entry nameQ5TLG6_9CNID
AccessionPrimary (citable) accession number: Q5TLG6
Entry history
Integrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: June 11, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)