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Q5TLG3

- Q5TLG3_HUMAN

UniProt

Q5TLG3 - Q5TLG3_HUMAN

Protein
Submitted name:

CD72 antigen

Gene

CD72

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 84 (01 Oct 2014)
      Sequence version 1 (10 May 2005)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. carbohydrate binding Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    CD72 antigenImported
    Submitted name:
    CD72 antigen, isoform CRA_aImported
    Submitted name:
    CD72 moleculeImported
    Gene namesi
    Name:CD72Imported
    ORF Names:hCG_2011491Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA26235.

    Structurei

    3D structure databases

    SMRiQ5TLG3. Positions 233-351.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG002477.
    KOiK06504.
    OMAiICEMTAF.
    PhylomeDBiQ5TLG3.

    Family and domain databases

    Gene3Di3.10.100.10. 1 hit.
    InterProiIPR001304. C-type_lectin.
    IPR016186. C-type_lectin-like.
    IPR016187. C-type_lectin_fold.
    [Graphical view]
    PfamiPF00059. Lectin_C. 1 hit.
    [Graphical view]
    SMARTiSM00034. CLECT. 1 hit.
    [Graphical view]
    SUPFAMiSSF56436. SSF56436. 1 hit.
    PROSITEiPS50041. C_TYPE_LECTIN_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5TLG3-1 [UniParc]FASTAAdd to Basket

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    MAEAITYADL RFVKAPLKKS ISSRLGQDPG ADDDGEITYE NVQVPAVLGV    50
    PSSLASSVLG DKAAVKSEQP TASWRAVTSP AVGRILPCRT TCLRYLLLGL 100
    LLTCLLLGVT AICLGVRYLQ VSQQLQQTNR VLEVTNSSLR QQLRLKITQL 150
    GQSAEDLQGS RRELAQSQEA LQVEQRAHQA AEGQLQACQA DRQKTKETLQ 200
    SEEQQRRALE QKLSNMENRL KPFFTCGSAD TCCPSGWIMH QKSCFYISLT 250
    SKNWQESQKQ CETLSSKLAT FSEIYPQSHS YYFLNSLLPN GGSGNSYWTG 300
    LSSNKDWKLT DDTQRTRTYA QSSKCNKVHK TWSWWTLESE SCRSSLPYIC 350
    EMTAFRFPD 359
    Length:359
    Mass (Da):40,220
    Last modified:May 10, 2005 - v1
    Checksum:i87A52C028AC17E44
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    EF064751 Genomic DNA. Translation: ABK41934.1.
    AB180952 Genomic DNA. Translation: BAD72857.1.
    AB180953 Genomic DNA. Translation: BAD72858.1.
    AB180954 Genomic DNA. Translation: BAD72859.1.
    AB180959 Genomic DNA. Translation: BAD72864.1.
    CH471071 Genomic DNA. Translation: EAW58372.1.
    CH471071 Genomic DNA. Translation: EAW58373.1.
    RefSeqiNP_001773.1. NM_001782.2.
    UniGeneiHs.116481.

    Genome annotation databases

    GeneIDi971.
    KEGGihsa:971.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    EF064751 Genomic DNA. Translation: ABK41934.1 .
    AB180952 Genomic DNA. Translation: BAD72857.1 .
    AB180953 Genomic DNA. Translation: BAD72858.1 .
    AB180954 Genomic DNA. Translation: BAD72859.1 .
    AB180959 Genomic DNA. Translation: BAD72864.1 .
    CH471071 Genomic DNA. Translation: EAW58372.1 .
    CH471071 Genomic DNA. Translation: EAW58373.1 .
    RefSeqi NP_001773.1. NM_001782.2.
    UniGenei Hs.116481.

    3D structure databases

    SMRi Q5TLG3. Positions 233-351.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    DNASUi 971.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 971.
    KEGGi hsa:971.

    Organism-specific databases

    CTDi 971.
    PharmGKBi PA26235.

    Phylogenomic databases

    HOVERGENi HBG002477.
    KOi K06504.
    OMAi ICEMTAF.
    PhylomeDBi Q5TLG3.

    Miscellaneous databases

    GenomeRNAii 971.
    NextBioi 4064.

    Family and domain databases

    Gene3Di 3.10.100.10. 1 hit.
    InterProi IPR001304. C-type_lectin.
    IPR016186. C-type_lectin-like.
    IPR016187. C-type_lectin_fold.
    [Graphical view ]
    Pfami PF00059. Lectin_C. 1 hit.
    [Graphical view ]
    SMARTi SM00034. CLECT. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56436. SSF56436. 1 hit.
    PROSITEi PS50041. C_TYPE_LECTIN_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The sequence of the human genome."
      Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D., Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q., Kodira C.D., Zheng X.H.
      , Chen L., Skupski M., Subramanian G., Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S., Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J., Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R., Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A., Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K., Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V., Brandon R., Cargill M., Chandramouliswaran I., Charlab R., Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K., Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z., Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A., Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V., Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B., Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J., Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C., Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L., Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S., Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A., Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D., Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L., Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N., Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S., Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F., Kline L., Koduru S., Love A., Mann F., May D., McCawley S., McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K., Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M., Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C., Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N., Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M., Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F., Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A., Mi H., Lazareva B., Hatton T., Narechania A., Diemer K., Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R., Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J., Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H., Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D., Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A., Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S., Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L., Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W., McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M., Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J., Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E., Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X.
      Science 291:1304-1351(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    2. "CD72 polymorphisms associated with alternative splicing modify susceptibility to human systemic lupus erythematosus through epistatic interaction with FCGR2B."
      Hitomi Y., Tsuchiya N., Kawasaki A., Ohashi J., Suzuki T., Kyogoku C., Fukazawa T., Bejrachandra S., Siriboonrit U., Chandanayingyong D., Suthipinittharm P., Tsao B.P., Hashimoto H., Honda Z., Tokunaga K.
      Hum. Mol. Genet. 13:2907-2917(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    3. Cited for: NUCLEOTIDE SEQUENCE.
    4. Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ5TLG3_HUMAN
    AccessioniPrimary (citable) accession number: Q5TLG3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 10, 2005
    Last sequence update: May 10, 2005
    Last modified: October 1, 2014
    This is version 84 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.