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Protein

Mitochondrial pyruvate carrier

Gene

MPC1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Mediates the uptake of pyruvate into mitochondria.UniRule annotation

GO - Biological processi

Keywordsi

Biological processTransportUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Mitochondrial pyruvate carrierUniRule annotation
Gene namesi
Name:MPC1Imported
Synonyms:BRP44LImported
ORF Names:hCG_15016Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiHostDB:ENSG00000060762.18
HGNCiHGNC:21606 MPC1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membraneUniRule annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000060762

PTM / Processingi

Proteomic databases

MaxQBiQ5TI65
PeptideAtlasiQ5TI65

Expressioni

Gene expression databases

BgeeiENSG00000060762

Family & Domainsi

Sequence similaritiesi

Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. [View classification]UniRule annotation

Phylogenomic databases

eggNOGiKOG1590 Eukaryota
ENOG4111TU9 LUCA
GeneTreeiENSGT00510000046988
HOGENOMiHOG000188911

Family and domain databases

InterProiView protein in InterPro
IPR005336 MPC
PfamiView protein in Pfam
PF03650 MPC, 1 hit

Sequencei

Sequence statusi: Complete.

Q5TI65-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKSPEIISG RMTFALCCYS LTFMRFAYKV QPRNWLLFAC HATNEVAQLI
60
QGGRLIKHEM TKTASA
Length:66
Mass (Da):7,540
Last modified:December 21, 2004 - v1
Checksum:iB79104C4D22099A4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL022069 Genomic DNA No translation available.
CH471051 Genomic DNA Translation: EAW47527.1
CH471051 Genomic DNA Translation: EAW47528.1
CH471051 Genomic DNA Translation: EAW47529.1
CH471051 Genomic DNA Translation: EAW47530.1
CH471051 Genomic DNA Translation: EAW47531.1
RefSeqiNP_001257808.1, NM_001270879.1
XP_011534196.1, XM_011535894.1
XP_011534197.1, XM_011535895.1
UniGeneiHs.172755

Genome annotation databases

EnsembliENST00000341756; ENSP00000340784; ENSG00000060762
ENST00000621685; ENSP00000477853; ENSG00000060762
GeneIDi51660
UCSCiuc031sra.2 human

Similar proteinsi

Entry informationi

Entry nameiQ5TI65_HUMAN
AccessioniPrimary (citable) accession number: Q5TI65
Secondary accession number(s): H7BXW7
Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: April 25, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported