Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein PRR14L

Gene

PRR14L

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein PRR14L
Alternative name(s):
Proline rich 14-like protein
Gene namesi
Name:PRR14L
Synonyms:C22orf30
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 22

Organism-specific databases

HGNCiHGNC:28738. PRR14L.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA145149425.

Polymorphism and mutation databases

BioMutaiPRR14L.
DMDMi74746580.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 21512151Protein PRR14LPRO_0000295739Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei157 – 1571PhosphoserineCombined sources
Modified residuei582 – 5821PhosphoserineCombined sources
Modified residuei945 – 9451PhosphoserineCombined sources
Modified residuei1029 – 10291PhosphoserineCombined sources

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ5THK1.
MaxQBiQ5THK1.
PaxDbiQ5THK1.
PeptideAtlasiQ5THK1.
PRIDEiQ5THK1.

PTM databases

iPTMnetiQ5THK1.
PhosphoSiteiQ5THK1.
SwissPalmiQ5THK1.

Expressioni

Gene expression databases

BgeeiQ5THK1.
CleanExiHS_C22orf30.
ExpressionAtlasiQ5THK1. baseline and differential.
GenevisibleiQ5THK1. HS.

Organism-specific databases

HPAiHPA062645.

Interactioni

Protein-protein interaction databases

BioGridi128956. 18 interactions.
IntActiQ5THK1. 12 interactions.
STRINGi9606.ENSP00000331845.

Structurei

3D structure databases

ProteinModelPortaliQ5THK1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IDZ1. Eukaryota.
ENOG4111V15. LUCA.
GeneTreeiENSGT00520000055626.
InParanoidiQ5THK1.
OMAiPHRTCKK.
OrthoDBiEOG7ZPNMP.
PhylomeDBiQ5THK1.
TreeFamiTF328446.

Family and domain databases

InterProiIPR026320. PRR14.
IPR028149. Tantalus-like.
[Graphical view]
PANTHERiPTHR14522. PTHR14522. 1 hit.
PfamiPF15386. Tantalus. 1 hit.
[Graphical view]

Sequences (4)i

Sequence statusi: Complete.

This entry describes 4 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q5THK1-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MLSSGVETQP VPLDSSMSAV VQELYSELPV SVSRELHADP EPSVIPDVKP
60 70 80 90 100
GASSSLLSQN RALPLELQRT HVESCCEETY ETLDHGSEPG RCGLVDSTAG
110 120 130 140 150
GSVASGILDR AKRSESMEPK VFRDPGGQAG IIREPSEGAK EDPHQHSTAA
160 170 180 190 200
EEKTSPSQED LLMQSSKELS HVDLPEDFLR SKEGNVQITA ETLLKSAEVQ
210 220 230 240 250
GMKVNGTKTD NNEGHKNGNV SKDLSAGCGE FQEVDKIMTS DEVSETSTLV
260 270 280 290 300
TPEPLTFVDP VLTEATPKEK ECEELKSCPW LSLPGNSAIS NVDNGKEELC
310 320 330 340 350
KPNLVCEADD NHQQLHGHHN EQPSSTHDSP TATSPLKENS EVSCFTSDLS
360 370 380 390 400
GPESRTISLE NCGFEGGGLL KRSAEKTDSS YFYRGDDQGK NLASREENEE
410 420 430 440 450
RLLIPRSERG GPFLFNAREP EKEISGRCSG EKEPVVSPKE NIHNNCIQDS
460 470 480 490 500
LHTGNSSSLM PNSFTEATEV MLNKNDLKIT VHVQGNLTNP EDHKETFTNM
510 520 530 540 550
SHPGGHSEES SFSSLMQIEE AGQTTPVEPN ILSKSFYTKD CNSLVSIQRN
560 570 580 590 600
LEGNTQLNEA SCNDFLFERK SIVSLMPEDQ ISPVSEVLKP KQGTALLLPS
610 620 630 640 650
PEFDYRPESE KVIQTSHDDI PLLDEQSIAC EMNELSCTNE LVVNKVESEC
660 670 680 690 700
VLNQQVSLNS QEHANLPTDS LLHLNKEMPL ATGRDAHQSH HPPLEGRADV
710 720 730 740 750
IADIQTIPIQ TKIKDISPPG NQTCGASSNC PTLNIKPVSL ERKKEMADSG
760 770 780 790 800
TKALHSRLRS NKREAAGFPQ VVSVIECHSV QSQDISSCHR VRKNVSQENM
810 820 830 840 850
CSASAAFKSS KISLQVDNSL ITKYENAFQH RDHCCQGTGH SVEKSSCKVS
860 870 880 890 900
YTSQERELDG KETNGSLPGD KIRNKMVAGL LNSGISNKTI HTSSSIKLSE
910 920 930 940 950
EGLEGKEQDV SKETVFCKYN ISDHAIQELN QTVNIPGPEK VLDQSPTVMF
960 970 980 990 1000
SSFKNVKSVE TLDQKADEVL DCQSNQNRPD ECKSEGQSAK EMLSSDQRET
1010 1020 1030 1040 1050
VTEPHGEVNH NQKDLLVSSG SNNSLPCGSP KKCNLKGAFV KMSGCDESTE
1060 1070 1080 1090 1100
GMVDIVYTDC SNKLAEGVLD VKASNLLDCG ARQEKLAFQE DSRSTLSRRE
1110 1120 1130 1140 1150
LDAAHTGTTG QDSDFPVTAA STVDFLKIKK SCEENVCRSL KDCEMEKCPD
1160 1170 1180 1190 1200
SCAHEMESVA DHEPNKRILG RVNLSLNDSH YGQQDKGTSL RETQEMTEGS
1210 1220 1230 1240 1250
RLEPNSEFGK ESTFGISSKE SMSCHDESSV SLRSLKSIEI MPSQENSETN
1260 1270 1280 1290 1300
VNSEETDLKN LCKPKDGEML CENVKDCTVL PEMKEIVSRD WSNSSDRDSV
1310 1320 1330 1340 1350
CTCVEKNACK ACHPHENSSD RHLPLTVKTD IKVKGEETEE HQRGRLGYLT
1360 1370 1380 1390 1400
VGEQSEELVT RETGDGDPVS NISQTHFKCR GILNHAEKQQ SPEVLDYMLQ
1410 1420 1430 1440 1450
KEEKYIRQQK AHTISQQCIS SSLLLDDAQN QNQPKADKDE STMINEITLA
1460 1470 1480 1490 1500
KLAKDSIVAQ TQKLEDQKEE RLHHPLRKDT ESCTSPCLLG APRKAQDPSS
1510 1520 1530 1540 1550
AGCDQIHGAF AKKGVLPLKK QPHRTCKKVS YQEQIIVGRK IGKIRSSAFL
1560 1570 1580 1590 1600
KSSSNPIPTK AHRLLSLCTL SAPTRLEPET APTKSLVSHI PKQMSTPCHP
1610 1620 1630 1640 1650
LRSLNFRKTT KESALLNKLS ILASKLAPAM KTQKLRYRRC SSELLPMAKS
1660 1670 1680 1690 1700
YKRLRYKRLL DGFSSSTEQL NPYLAASGWD KRPNSKPMAL YSLESIKMTF
1710 1720 1730 1740 1750
IDLSNKMPSL LFGSEIFPVS FHVKSSSSDC TTESSRTFPE HCAPARLALG
1760 1770 1780 1790 1800
EALQCPSQPP KWTFSFFLSH GCPGMATFRE DTGVHSQTHT QAPPQPPAPL
1810 1820 1830 1840 1850
QDYGGTAIVQ TRADCSVLGL HTLLALCSPG CYRIWTKKRS FSSHMPTMQR
1860 1870 1880 1890 1900
LFMTQFTQGL KGLRSPASIA DKVFCSLPYS VGRVLSIWSQ HGPSVCSFEI
1910 1920 1930 1940 1950
SSLHSPHCKR QPSLGTTSSH TMLPYVPLPG MEATYNTSGS QTRLEPPFPA
1960 1970 1980 1990 2000
LVPKSCLVAE SAVSKLLLSA SEFQVRGLDE LDGVKAACPC PQSSPPEQKE
2010 2020 2030 2040 2050
AEPEKRPKKV SQIRIRKTIP RPDPNLTPMG LPRPKRLKKK EFSLEEIYTN
2060 2070 2080 2090 2100
KNYKSPPANR CLETIFEEPK ERNGTLISIS QQKRKRVLEF QDFTVPRKRR
2110 2120 2130 2140 2150
ARGKVKVAGS FTRAQKAAVQ SRELDALLIQ KLMELETFFA KEEEQEQSSG

C
Length:2,151
Mass (Da):237,300
Last modified:December 21, 2004 - v1
Checksum:iA1E0277094885E1F
GO
Isoform 2 (identifier: Q5THK1-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     2001-2151: AEPEKRPKKV...EEEQEQSSGC → VKEEGV

Note: No experimental confirmation available.
Show »
Length:2,006
Mass (Da):220,377
Checksum:iBE3CD185A946DA43
GO
Isoform 3 (identifier: Q5THK1-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1234-1239: SLKSIE → SPCLTT
     1240-2151: Missing.

Note: No experimental confirmation available.
Show »
Length:1,239
Mass (Da):135,393
Checksum:iA755F4609C90D017
GO
Isoform 4 (identifier: Q5THK1-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     2061-2151: CLETIFEEPK...EEEQEQSSGC → DLDSSCPSTD...TWAGRGDSSL

Note: No experimental confirmation available.
Show »
Length:2,149
Mass (Da):236,883
Checksum:i1936AAA31D63A913
GO

Sequence cautioni

The sequence AAH40859.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAB15536.1 differs from that shown. Reason: Frameshift at position 1174. Curated
The sequence BAB15536.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAC85470.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAC85533.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence CAI22445.1 differs from that shown. Reason: Erroneous gene model prediction. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti885 – 8851I → N in BAB15536 (PubMed:14702039).Curated
Sequence conflicti1223 – 12231S → F in BAB15536 (PubMed:14702039).Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti455 – 4551N → S.
Corresponds to variant rs140081 [ dbSNP | Ensembl ].
VAR_059641
Natural varianti740 – 7401L → P.
Corresponds to variant rs140080 [ dbSNP | Ensembl ].
VAR_059642
Natural varianti876 – 8761M → I.
Corresponds to variant rs17821493 [ dbSNP | Ensembl ].
VAR_059643
Natural varianti961 – 9611T → I.
Corresponds to variant rs140079 [ dbSNP | Ensembl ].
VAR_059644
Natural varianti963 – 9631D → N.
Corresponds to variant rs9619227 [ dbSNP | Ensembl ].
VAR_059645
Natural varianti1151 – 11511S → P.
Corresponds to variant rs12159328 [ dbSNP | Ensembl ].
VAR_059646
Natural varianti1221 – 12211S → L.
Corresponds to variant rs140078 [ dbSNP | Ensembl ].
VAR_059647
Natural varianti1316 – 13161E → K.
Corresponds to variant rs61461793 [ dbSNP | Ensembl ].
VAR_061637
Natural varianti1395 – 13951L → F.
Corresponds to variant rs3804090 [ dbSNP | Ensembl ].
VAR_059648
Natural varianti1784 – 17841V → I.
Corresponds to variant rs16989427 [ dbSNP | Ensembl ].
VAR_059649

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1234 – 12396SLKSIE → SPCLTT in isoform 3. 1 PublicationVSP_027046
Alternative sequencei1240 – 2151912Missing in isoform 3. 1 PublicationVSP_027047Add
BLAST
Alternative sequencei2001 – 2151151AEPEK…QSSGC → VKEEGV in isoform 2. 1 PublicationVSP_027048Add
BLAST
Alternative sequencei2061 – 215191CLETI…QSSGC → DLDSSCPSTDSETGHFLVFG YAQRQAQPHPLLASRRLIGC SSPEGRGHPRSYPYWRRLLV LCWYLPGWRAGRVTWLRLAT WAGRGDSSL in isoform 4. 1 PublicationVSP_027049Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT841517 mRNA. Translation: CAJ86447.1.
AL031255, AC005004 Genomic DNA. Translation: CAI22445.1. Sequence problems.
AL031255, AC005004 Genomic DNA. Translation: CAI22448.1.
AK026712 mRNA. Translation: BAB15536.1. Sequence problems.
AK123082 mRNA. Translation: BAC85533.1. Different initiation.
AK130944 mRNA. Translation: BAC85470.1. Different initiation.
BC040859 mRNA. Translation: AAH40859.1. Different initiation.
CCDSiCCDS13900.2. [Q5THK1-1]
RefSeqiNP_775837.2. NM_173566.2. [Q5THK1-1]
XP_006724282.1. XM_006724219.2. [Q5THK1-1]
XP_006724283.1. XM_006724220.2. [Q5THK1-1]
XP_011528382.1. XM_011530080.1. [Q5THK1-1]
XP_011528383.1. XM_011530081.1. [Q5THK1-1]
UniGeneiHs.438906.

Genome annotation databases

EnsembliENST00000327423; ENSP00000331845; ENSG00000183530. [Q5THK1-1]
GeneIDi253143.
KEGGihsa:253143.
UCSCiuc003alp.5. human. [Q5THK1-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT841517 mRNA. Translation: CAJ86447.1.
AL031255, AC005004 Genomic DNA. Translation: CAI22445.1. Sequence problems.
AL031255, AC005004 Genomic DNA. Translation: CAI22448.1.
AK026712 mRNA. Translation: BAB15536.1. Sequence problems.
AK123082 mRNA. Translation: BAC85533.1. Different initiation.
AK130944 mRNA. Translation: BAC85470.1. Different initiation.
BC040859 mRNA. Translation: AAH40859.1. Different initiation.
CCDSiCCDS13900.2. [Q5THK1-1]
RefSeqiNP_775837.2. NM_173566.2. [Q5THK1-1]
XP_006724282.1. XM_006724219.2. [Q5THK1-1]
XP_006724283.1. XM_006724220.2. [Q5THK1-1]
XP_011528382.1. XM_011530080.1. [Q5THK1-1]
XP_011528383.1. XM_011530081.1. [Q5THK1-1]
UniGeneiHs.438906.

3D structure databases

ProteinModelPortaliQ5THK1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi128956. 18 interactions.
IntActiQ5THK1. 12 interactions.
STRINGi9606.ENSP00000331845.

PTM databases

iPTMnetiQ5THK1.
PhosphoSiteiQ5THK1.
SwissPalmiQ5THK1.

Polymorphism and mutation databases

BioMutaiPRR14L.
DMDMi74746580.

Proteomic databases

EPDiQ5THK1.
MaxQBiQ5THK1.
PaxDbiQ5THK1.
PeptideAtlasiQ5THK1.
PRIDEiQ5THK1.

Protocols and materials databases

DNASUi253143.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000327423; ENSP00000331845; ENSG00000183530. [Q5THK1-1]
GeneIDi253143.
KEGGihsa:253143.
UCSCiuc003alp.5. human. [Q5THK1-1]

Organism-specific databases

CTDi253143.
GeneCardsiPRR14L.
HGNCiHGNC:28738. PRR14L.
HPAiHPA062645.
neXtProtiNX_Q5THK1.
PharmGKBiPA145149425.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IDZ1. Eukaryota.
ENOG4111V15. LUCA.
GeneTreeiENSGT00520000055626.
InParanoidiQ5THK1.
OMAiPHRTCKK.
OrthoDBiEOG7ZPNMP.
PhylomeDBiQ5THK1.
TreeFamiTF328446.

Miscellaneous databases

ChiTaRSiPRR14L. human.
GenomeRNAii253143.
PROiQ5THK1.

Gene expression databases

BgeeiQ5THK1.
CleanExiHS_C22orf30.
ExpressionAtlasiQ5THK1. baseline and differential.
GenevisibleiQ5THK1. HS.

Family and domain databases

InterProiIPR026320. PRR14.
IPR028149. Tantalus-like.
[Graphical view]
PANTHERiPTHR14522. PTHR14522. 1 hit.
PfamiPF15386. Tantalus. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "A genome annotation-driven approach to cloning the human ORFeome."
    Collins J.E., Wright C.L., Edwards C.A., Davis M.P., Grinham J.A., Cole C.G., Goward M.E., Aguado B., Mallya M., Mokrab Y., Huckle E.J., Beare D.M., Dunham I.
    Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
  2. "The DNA sequence of human chromosome 22."
    Dunham I., Hunt A.R., Collins J.E., Bruskiewich R., Beare D.M., Clamp M., Smink L.J., Ainscough R., Almeida J.P., Babbage A.K., Bagguley C., Bailey J., Barlow K.F., Bates K.N., Beasley O.P., Bird C.P., Blakey S.E., Bridgeman A.M.
    , Buck D., Burgess J., Burrill W.D., Burton J., Carder C., Carter N.P., Chen Y., Clark G., Clegg S.M., Cobley V.E., Cole C.G., Collier R.E., Connor R., Conroy D., Corby N.R., Coville G.J., Cox A.V., Davis J., Dawson E., Dhami P.D., Dockree C., Dodsworth S.J., Durbin R.M., Ellington A.G., Evans K.L., Fey J.M., Fleming K., French L., Garner A.A., Gilbert J.G.R., Goward M.E., Grafham D.V., Griffiths M.N.D., Hall C., Hall R.E., Hall-Tamlyn G., Heathcott R.W., Ho S., Holmes S., Hunt S.E., Jones M.C., Kershaw J., Kimberley A.M., King A., Laird G.K., Langford C.F., Leversha M.A., Lloyd C., Lloyd D.M., Martyn I.D., Mashreghi-Mohammadi M., Matthews L.H., Mccann O.T., Mcclay J., Mclaren S., McMurray A.A., Milne S.A., Mortimore B.J., Odell C.N., Pavitt R., Pearce A.V., Pearson D., Phillimore B.J.C.T., Phillips S.H., Plumb R.W., Ramsay H., Ramsey Y., Rogers L., Ross M.T., Scott C.E., Sehra H.K., Skuce C.D., Smalley S., Smith M.L., Soderlund C., Spragon L., Steward C.A., Sulston J.E., Swann R.M., Vaudin M., Wall M., Wallis J.M., Whiteley M.N., Willey D.L., Williams L., Williams S.A., Williamson H., Wilmer T.E., Wilming L., Wright C.L., Hubbard T., Bentley D.R., Beck S., Rogers J., Shimizu N., Minoshima S., Kawasaki K., Sasaki T., Asakawa S., Kudoh J., Shintani A., Shibuya K., Yoshizaki Y., Aoki N., Mitsuyama S., Roe B.A., Chen F., Chu L., Crabtree J., Deschamps S., Do A., Do T., Dorman A., Fang F., Fu Y., Hu P., Hua A., Kenton S., Lai H., Lao H.I., Lewis J., Lewis S., Lin S.-P., Loh P., Malaj E., Nguyen T., Pan H., Phan S., Qi S., Qian Y., Ray L., Ren Q., Shaull S., Sloan D., Song L., Wang Q., Wang Y., Wang Z., White J., Willingham D., Wu H., Yao Z., Zhan M., Zhang G., Chissoe S., Murray J., Miller N., Minx P., Fulton R., Johnson D., Bemis G., Bentley D., Bradshaw H., Bourne S., Cordes M., Du Z., Fulton L., Goela D., Graves T., Hawkins J., Hinds K., Kemp K., Latreille P., Layman D., Ozersky P., Rohlfing T., Scheet P., Walker C., Wamsley A., Wohldmann P., Pepin K., Nelson J., Korf I., Bedell J.A., Hillier L.W., Mardis E., Waterston R., Wilson R., Emanuel B.S., Shaikh T., Kurahashi H., Saitta S., Budarf M.L., McDermid H.E., Johnson A., Wong A.C.C., Morrow B.E., Edelmann L., Kim U.J., Shizuya H., Simon M.I., Dumanski J.P., Peyrard M., Kedra D., Seroussi E., Fransson I., Tapia I., Bruder C.E., O'Brien K.P., Wilkinson P., Bodenteich A., Hartman K., Hu X., Khan A.S., Lane L., Tilahun Y., Wright H.
    Nature 402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 619-2151 (ISOFORM 3), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1332-2151 (ISOFORM 2), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1945-2151 (ISOFORM 1).
    Tissue: Adrenal gland, Lung and Uterus.
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1699-2151 (ISOFORM 4).
    Tissue: Uterus.
  5. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-157, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Embryonic kidney.
  6. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1029, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  7. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
    Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  8. "Toward a comprehensive characterization of a human cancer cell phosphoproteome."
    Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J., Mohammed S.
    J. Proteome Res. 12:260-271(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-582; SER-945 AND SER-1029, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Erythroleukemia.

Entry informationi

Entry nameiPR14L_HUMAN
AccessioniPrimary (citable) accession number: Q5THK1
Secondary accession number(s): Q5THK4
, Q6ZNN1, Q6ZWH0, Q8IW74, Q9H5T4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: December 21, 2004
Last modified: July 6, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 22
    Human chromosome 22: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.