Q5THJ1 (Q5THJ1_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
PR domain zinc finger protein 2 Ensembl ENSP00000411103 Ensembl ENSP00000341621

Gene names

Name:

PRDM2 Ensembl ENSP00000411103 Ensembl ENSP00000341621

Organism

Homo sapiens (Human) [Reference proteome] Ensembl ENSP00000411103

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	1481 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000411103 Ensembl ENSP00000341621

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro
Cellular_component	Golgi apparatus Inferred from direct assay. Source: HPA nucleus Inferred from direct assay. Source: HPA
Molecular_function	DNA binding Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5THJ1 [UniParc]. Last modified December 21, 2004. Version 1. Checksum: 87F7398540D3A5F3	FASTA	1,481	162,107
	10 20 30 40 50 60 MRDSAEGPKE DEEKPSASAL EQPATLQEVA SQEVPPELAT PAPAWEPQPE PDERLEAAAC 70 80 90 100 110 120 EVNDLGEEEE EEEEEDEEEE EDDDDDELED EGEEEASMPN ENSVKEPEIR CDEKPEDLLE 130 140 150 160 170 180 EPKTTSEETL EDCSEVTPAM QIPRTKEEAN GDVFETFMFP CQHCERKFTT KQGLERHMHI 190 200 210 220 230 240 HISTVNHAFK CKYCGKAFGT QINRRRHERR HEAGLKRKPS QTLQPSEDLA DGKASGENVA 250 260 270 280 290 300 SKDDSSPPSL GPDCLIMNSE KASQDTINSS VVEENGEVKE LHPCKYCKKV FGTHTNMRRH 310 320 330 340 350 360 QRRVHERHLI PKGVRRKGGL EEPQPPAEQA QATQNVYVPS TEPEEEGEAD DVYIMDISSN 370 380 390 400 410 420 ISENLNYYID GKIQTNNNTS NCDVIEMESA SADLYGINCL LTPVTVEITQ NIKTTQVPVT 430 440 450 460 470 480 EDLPKEPLGS TNSEAKKRRT ASPPALPKIK AETDSDPMVP SCSLSLPLSI STTEAVSFHK 490 500 510 520 530 540 EKSVYLSSKL KQLLQTQDKL TPAGISATEI AKLGPVCVSA PASMLPVTSS RFKRRTSSPP 550 560 570 580 590 600 SSPQHSPALR DFGKPSDGKA AWTDAGLTSK KSKLESHSDS PAWSLSGRDE RETVSPPCFD 610 620 630 640 650 660 EYKMSKEWTA SSAFSSVCNQ QPLDLSSGVK QKAEGTGKTP VQWESVLDLS VHKKHCSDSE 670 680 690 700 710 720 GKEFKESHSV QPTCSAVKKR KPTTCMLQKV LLNEYNGIDL PVENPADGTR SPSPCKSLEA 730 740 750 760 770 780 QPDPDLGPGS GFPAPTVEST PDVCPSSPAL QTPSLSSGQL PPLLIPTDPS SPPPCPPVLT 790 800 810 820 830 840 VATPPPPLLP TVPLPAPSSS ASPHPCPSPL SNATAQSPLP ILSPTVSPSP SPIPPVEPLM 850 860 870 880 890 900 SAASPGPPTL SSSSSSSSSS SSFSSSSSSS SPSPPPLSAI SSVVSSGDNL EASLPMISFK 910 920 930 940 950 960 QEELENEGLK PREEPQSAAE QDVVVQETFN KNFVCNVCES PFLSIKDLTK HLSIHAEEWP 970 980 990 1000 1010 1020 FKCEFCVQLF KDKTDLSEHR FLLHGVGNIF VCSVCKKEFA FLCNLQQHQR DLHPDKVCTH 1030 1040 1050 1060 1070 1080 HEFESGTLRP QNFTDPSKAH VEHMQSLPED PLETSKEEEE LNDSSEELYT TIKIMASGIK 1090 1100 1110 1120 1130 1140 TKDPDVRLGL NQHYPSFKPP PFQYHHRNPM GIGVTATNFT THNIPQTFTT AIRCTKCGKG 1150 1160 1170 1180 1190 1200 VDNMPELHKH ILACASASDK KRYTPKKNPV PLKQTVQPKN GVVVLDNSGK NAFRRMGQPK 1210 1220 1230 1240 1250 1260 RLNFSVELSK MSSNKLKLNA LKKKNQLVQK AILQKNKSAK QKADLKNACE SSSHICPYCN 1270 1280 1290 1300 1310 1320 REFTYIGSLN KHAAFSCPKK PLSPPKKKVS HSSKKGGHSS PASSDKNSNS NHRRRTADAE 1330 1340 1350 1360 1370 1380 IKMQSMQTPL GKTRARSSGP TQVPLPSSSF RSKQNVKFAA SVKSKKPSSS SLRNSSPIRM 1390 1400 1410 1420 1430 1440 AKITHVEGKK PKAVAKNHSA QLSSKTSRSL HVRVQKSKAV LQSKSTLASK KRTDRFNIKS 1450 1460 1470 1480 RERSGGPVTR SLQLAAAADL SENKREDGSA KQELKDFRNF L

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The DNA sequence and biological annotation of human chromosome 1." Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K. , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S., McLaren S., Milne S., Mistry S., Moore M.J., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R., Banerjee R., Bryant S.P., Burford D.C., Burrill W.D., Clegg S.M., Dhami P., Dovey O., Faulkner L.M., Gribble S.M., Langford C.F., Pandian R.D., Porter K.M., Prigmore E. Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL031277 Genomic DNA. No translation available. AL359771 Genomic DNA. No translation available. AL583942 Genomic DNA. No translation available.
IPI	IPI00472974.
RefSeq	NP_001007258.1. NM_001007257.2.
UniGene	Hs.371823.
3D structure databases
SMR	Q5THJ1. Positions 151-214, 251-305, 934-1016, 1245-1284.
ModBase	Search...
Protocols and materials databases
DNASU	7799.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000343137; ENSP00000341621; ENSG00000116731. ENST00000413440; ENSP00000411103; ENSG00000116731.
GeneID	7799.
KEGG	hsa:7799.
UCSC	uc001avk.3. human.
Organism-specific databases
CTD	7799.
HGNC	HGNC:9347. PRDM2.
PharmGKB	PA33715.
GenAtlas	Search...
Phylogenomic databases
HOGENOM	HOG000231078.
HOVERGEN	HBG053671.
KO	K11432.
Family and domain databases
Gene3D	3.30.160.60. 1 hit.
InterPro	IPR009170. RIZ_retinblastoma-bd_prot. IPR007087. Znf_C2H2. IPR015880. Znf_C2H2-like. IPR013087. Znf_C2H2/integrase_DNA-bd. [Graphical view]
Pfam	PF00096. zf-C2H2. 2 hits. [Graphical view]
PIRSF	PIRSF002395. RIZ_SET. 1 hit.
SMART	SM00355. ZnF_C2H2. 8 hits. [Graphical view]
PROSITE	PS00028. ZINC_FINGER_C2H2_1. 6 hits. PS50157. ZINC_FINGER_C2H2_2. 7 hits. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	7799.
NextBio	30170.

Entry information

Entry name

Q5THJ1_HUMAN

Accession

Primary (citable) accession number: Q5THJ1
Secondary accession number(s): B5MC68

Entry history

Integrated into UniProtKB/TrEMBL:	December 21, 2004
Last sequence update:	December 21, 2004
Last modified:	May 29, 2013
This is version 84 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.