Q5TGI4 (SAMD5_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Sterile alpha motif domain-containing protein 5
Short name=SAM domain-containing protein 5

Gene names

Name:	SAMD5
Synonyms:	SAMDC1

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	173 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 SAM (sterile alpha motif) domain.

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 173	173	Sterile alpha motif domain-containing protein 5		PRO_0000311361
Regions
	Domain	1 – 65	65	SAM

Sequences

	Sequence		Length	Mass (Da)
	Q5TGI4 [UniParc]. Last modified December 21, 2004. Version 1. Checksum: 6869A7A22FD73745	FASTA	173	19,231
	10 20 30 40 50 60 MCTNIVYEWL KALQLPQYAE SFVDNGYDDL EVCKQIGDPD LDAIGVLAPA HRRRILEAVR 70 80 90 100 110 120 RLREQDANAA GLYFTLEPQP APPGPPADAV PTGRRGEPCG GPAQGTRGDS RGHTTAPRSR 130 140 150 160 170 ELVSYPKLKL KIMIRDKLVR DGIHLSKPPY SRKVPMAGIL EYLMNWPKSS QSR

References

[1]

"The DNA sequence and analysis of human chromosome 6." Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D. , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P., Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V., Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J., Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E., Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A., Frankland J., French L., Garner P., Garnett J., Ghori M.J., Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M., Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S., Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R., Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E., Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A., Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K., McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T., Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R., Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W., Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M., Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L., Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J., Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L., Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W., Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S. Nature 425:805-811(2003) [PubMed: 14574404] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL354880, AL034350 Genomic DNA. Translation: CAI18904.1. AL034350, AL354880 Genomic DNA. Translation: CAI23090.1.
IPI	IPI00374317.
RefSeq	NP_001025231.1. NM_001030060.2.
UniGene	Hs.567973.
3D structure databases
HSSP	HSSP built from PDB template 1B4F based on UniProtKB P29323.
ProteinModelPortal	Q5TGI4.
SMR	Q5TGI4. Positions 3-62.
ModBase	Search...
Polymorphism databases
DMDM	74746493.
Proteomic databases
PRIDE	Q5TGI4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000367474; ENSP00000356444; ENSG00000203727.
GeneID	389432.
KEGG	hsa:389432.
UCSC	uc003qmc.1. human.
Organism-specific databases
CTD	389432.
GeneCards	GC06P147873.
HGNC	HGNC:21180. SAMD5.
neXtProt	NX_Q5TGI4.
PharmGKB	PA134888862.
GenAtlas	Search...
Phylogenomic databases
eggNOG	prNOG18312.
GeneTree	ENSGT00510000048701.
HOGENOM	HBG713017.
HOVERGEN	HBG096715.
InParanoid	Q5TGI4.
OMA	GTRGDPR.
OrthoDB	EOG4VHK7N.
PhylomeDB	Q5TGI4.
Gene expression databases
ArrayExpress	Q5TGI4.
Bgee	Q5TGI4.
CleanEx	HS_SAMD5.
Genevestigator	Q5TGI4.
Family and domain databases
InterPro	IPR001660. SAM. IPR013761. SAM/pointed. IPR021129. SAM_type1. [Graphical view]
Gene3D	G3DSA:1.10.150.50. SAM_type. 1 hit.
Pfam	PF00536. SAM_1. 1 hit. [Graphical view]
SMART	SM00454. SAM. 1 hit. [Graphical view]
SUPFAM	SSF47769. SAM_homology. 1 hit.
PROSITE	PS50105. SAM_DOMAIN. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	102874.

Entry information

Entry name

SAMD5_HUMAN

Accession

Primary (citable) accession number: Q5TGI4

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 13, 2007
Last sequence update:	December 21, 2004
Last modified:	January 25, 2012
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.