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Protein
Submitted name:

HCG2029799, isoform CRA_b

Gene

PLG

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • protein domain specific binding Source: AgBase
  • receptor binding Source: AgBase

Names & Taxonomyi

Protein namesi
Submitted name:
HCG2029799, isoform CRA_bImported
Submitted name:
PlasminogenImported
Gene namesi
Name:PLGImported
ORF Names:hCG_2029799Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

HGNCiHGNC:9071. PLG.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000122194.
PharmGKBiPA33405.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_500770655320 – 136Sequence analysisAdd BLAST117

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PeptideAtlasiQ5TEH5.
PRIDEiQ5TEH5.

Expressioni

Gene expression databases

BgeeiENSG00000122194.
ExpressionAtlasiQ5TEH5. baseline and differential.

Interactioni

GO - Molecular functioni

  • protein domain specific binding Source: AgBase
  • receptor binding Source: AgBase

Protein-protein interaction databases

STRINGi9606.ENSP00000308938.

Structurei

3D structure databases

ProteinModelPortaliQ5TEH5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 98AppleInterPro annotationAdd BLAST83
Domaini102 – 136KringleInterPro annotationAdd BLAST35

Keywords - Domaini

KringlePROSITE-ProRule annotationSAAS annotation, SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IDXR. Eukaryota.
COG5640. LUCA.
GeneTreeiENSGT00760000119133.
HOGENOMiHOG000115578.
HOVERGENiHBG003051.

Family and domain databases

InterProiView protein in InterPro
IPR000001. Kringle.
IPR013806. Kringle-like.
IPR003609. Pan_app.
PfamiView protein in Pfam
PF00051. Kringle. 1 hit.
PF00024. PAN_1. 1 hit.
SMARTiView protein in SMART
SM00130. KR. 1 hit.
SM00473. PAN_AP. 1 hit.
SUPFAMiSSF57440. SSF57440. 1 hit.
PROSITEiView protein in PROSITE
PS50070. KRINGLE_2. 1 hit.
PS50948. PAN. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5TEH5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEHKEVVLLL LLFLKSGQGE PLDDYVNTQG ASLFSVTKKQ LGAGSIEECA
60 70 80 90 100
AKCEEDEEFT CRAFQYHSKE QQCVIMAENR KSSIIIRMRD VVLFEKKVYL
110 120 130
SECKTGNGKN YRGTMSKTKN GITCQKWSST SPHRPR
Length:136
Mass (Da):15,444
Last modified:December 21, 2004 - v1
Checksum:i617124AAABBD2A4B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL109933 Genomic DNA. No translation available.
CH471051 Genomic DNA. Translation: EAW47592.1.
RefSeqiNP_001161810.1. NM_001168338.1.
UniGeneiHs.143436.

Genome annotation databases

EnsembliENST00000366924; ENSP00000355891; ENSG00000122194.
GeneIDi5340.
UCSCiuc021zhr.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL109933 Genomic DNA. No translation available.
CH471051 Genomic DNA. Translation: EAW47592.1.
RefSeqiNP_001161810.1. NM_001168338.1.
UniGeneiHs.143436.

3D structure databases

ProteinModelPortaliQ5TEH5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000308938.

Proteomic databases

PeptideAtlasiQ5TEH5.
PRIDEiQ5TEH5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000366924; ENSP00000355891; ENSG00000122194.
GeneIDi5340.
UCSCiuc021zhr.2. human.

Organism-specific databases

CTDi5340.
HGNCiHGNC:9071. PLG.
OpenTargetsiENSG00000122194.
PharmGKBiPA33405.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IDXR. Eukaryota.
COG5640. LUCA.
GeneTreeiENSGT00760000119133.
HOGENOMiHOG000115578.
HOVERGENiHBG003051.

Miscellaneous databases

ChiTaRSiPLG. human.
GenomeRNAii5340.

Gene expression databases

BgeeiENSG00000122194.
ExpressionAtlasiQ5TEH5. baseline and differential.

Family and domain databases

InterProiView protein in InterPro
IPR000001. Kringle.
IPR013806. Kringle-like.
IPR003609. Pan_app.
PfamiView protein in Pfam
PF00051. Kringle. 1 hit.
PF00024. PAN_1. 1 hit.
SMARTiView protein in SMART
SM00130. KR. 1 hit.
SM00473. PAN_AP. 1 hit.
SUPFAMiSSF57440. SSF57440. 1 hit.
PROSITEiView protein in PROSITE
PS50070. KRINGLE_2. 1 hit.
PS50948. PAN. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ5TEH5_HUMAN
AccessioniPrimary (citable) accession number: Q5TEH5
Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: February 15, 2017
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.