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Protein
Submitted name:

Histone deacetylase 1

Gene

HDAC1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Histone deacetylase 1Imported
Gene namesi
Name:HDAC1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

HGNCiHGNC:4852. HDAC1.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000116478.

PTM / Processingi

Proteomic databases

MaxQBiQ5TEE2.
PeptideAtlasiQ5TEE2.
PRIDEiQ5TEE2.

Expressioni

Gene expression databases

BgeeiENSG00000116478.
ExpressionAtlasiQ5TEE2. baseline and differential.

Interactioni

Protein-protein interaction databases

MINTiMINT-1409030.

Structurei

3D structure databases

ProteinModelPortaliQ5TEE2.
SMRiQ5TEE2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini90 – 210Hist_deacetylInterPro annotationAdd BLAST121

Phylogenomic databases

GeneTreeiENSGT00530000062889.
HOGENOMiHOG000225180.
HOVERGENiHBG057112.

Family and domain databases

Gene3Di3.40.800.20. 2 hits.
InterProiIPR000286. His_deacetylse.
IPR003084. His_deacetylse_1.
IPR023801. His_deacetylse_dom.
[Graphical view]
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiPF00850. Hist_deacetyl. 1 hit.
[Graphical view]
PRINTSiPR01270. HDASUPER.
PR01271. HISDACETLASE.

Sequencei

Sequence statusi: Fragment.

Q5TEE2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQTQGTRRK VCYYYDGDVG NYYYGQGHPM KPHRIRMTHN LLLNYGLYRK
60 70 80 90 100
MEIYRPHKAN AEEMTKYHSD DYIKFLRSIR PDNMSEYSKQ MQRSSAVKLN
110 120 130 140 150
KQQTDIAVNW AGGLHHAKKS EASGFCYVND IVLAILELLK YHQRVLYIDI
160 170 180 190 200
DIHHGDGVEE AFYTTDRVMT VSFHKYGEYF PGTGDLRDIG AGKGKYYAVN
210
YPLRDGIDDE S
Length:211
Mass (Da):24,545
Last modified:December 21, 2004 - v1
Checksum:i56C9E4B3B5C82C3C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei211Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL109945 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000428704; ENSP00000407859; ENSG00000116478.
UCSCiuc057ekb.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL109945 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliQ5TEE2.
SMRiQ5TEE2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-1409030.

Proteomic databases

MaxQBiQ5TEE2.
PeptideAtlasiQ5TEE2.
PRIDEiQ5TEE2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000428704; ENSP00000407859; ENSG00000116478.
UCSCiuc057ekb.1. human.

Organism-specific databases

HGNCiHGNC:4852. HDAC1.
OpenTargetsiENSG00000116478.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00530000062889.
HOGENOMiHOG000225180.
HOVERGENiHBG057112.

Miscellaneous databases

ChiTaRSiHDAC1. human.

Gene expression databases

BgeeiENSG00000116478.
ExpressionAtlasiQ5TEE2. baseline and differential.

Family and domain databases

Gene3Di3.40.800.20. 2 hits.
InterProiIPR000286. His_deacetylse.
IPR003084. His_deacetylse_1.
IPR023801. His_deacetylse_dom.
[Graphical view]
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiPF00850. Hist_deacetyl. 1 hit.
[Graphical view]
PRINTSiPR01270. HDASUPER.
PR01271. HISDACETLASE.
ProtoNetiSearch...

Entry informationi

Entry nameiQ5TEE2_HUMAN
AccessioniPrimary (citable) accession number: Q5TEE2
Entry historyi
Integrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: November 2, 2016
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.