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Q5TBR1

- Q5TBR1_HUMAN

UniProt

Q5TBR1 - Q5TBR1_HUMAN

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Protein
Submitted name:

Sialic acid synthase

Gene

NANS

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. catalytic activity Source: InterPro

GO - Biological processi

  1. carbohydrate biosynthetic process Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Sialic acid synthaseImported
Gene namesi
Name:NANSImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 9

Organism-specific databases

HGNCiHGNC:19237. NANS.

PTM / Processingi

Proteomic databases

PRIDEiQ5TBR1.

Expressioni

Gene expression databases

ExpressionAtlasiQ5TBR1. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliQ5TBR1.
SMRiQ5TBR1. Positions 1-139.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000011081.
HOGENOMiHOG000284783.
HOVERGENiHBG000665.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR013132. Neu5Ac_N.
[Graphical view]
PfamiPF03102. NeuB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q5TBR1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVLVLDYSGR PMVISSGMQS MDTMKQVYQI VKPLNPNFCF LQCTSAYPLQ
60 70 80 90 100
PEDVNLRVIS EYQKLFPDIP IGYSGHETGI AISVAAVALG AKVLERHITL
110 120 130 140
DKTWKGSDHS ASLEPGELAE LVRSVRLVER ALGSPTKQLL
Length:140
Mass (Da):15,416
Last modified:December 21, 2004 - v1
Checksum:i62D28D0B4BDD2290
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei140 – 1401Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL137073 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000415280; ENSP00000404107; ENSG00000095380.
UCSCiuc004aye.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL137073 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali Q5TBR1.
SMRi Q5TBR1. Positions 1-139.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q5TBR1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000415280 ; ENSP00000404107 ; ENSG00000095380 .
UCSCi uc004aye.1. human.

Organism-specific databases

HGNCi HGNC:19237. NANS.
GenAtlasi Search...

Phylogenomic databases

GeneTreei ENSGT00390000011081.
HOGENOMi HOG000284783.
HOVERGENi HBG000665.

Miscellaneous databases

ChiTaRSi NANS. human.
NextBioi 35539881.

Gene expression databases

ExpressionAtlasi Q5TBR1. baseline and differential.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
InterProi IPR013785. Aldolase_TIM.
IPR013132. Neu5Ac_N.
[Graphical view ]
Pfami PF03102. NeuB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "DNA sequence and analysis of human chromosome 9."
    Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L.
    , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.
    Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiQ5TBR1_HUMAN
AccessioniPrimary (citable) accession number: Q5TBR1
Entry historyi
Integrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: October 29, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3