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Q5TBR0

- Q5TBR0_HUMAN

UniProt

Q5TBR0 - Q5TBR0_HUMAN

Protein
Submitted name:

Sialic acid synthase

Gene

NANS

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
  1. Functioni

    GO - Molecular functioni

    1. catalytic activity Source: InterPro

    GO - Biological processi

    1. carbohydrate biosynthetic process Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Sialic acid synthaseImported
    Gene namesi
    Name:NANSImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 9

    Organism-specific databases

    HGNCiHGNC:19237. NANS.

    PTM / Processingi

    Proteomic databases

    PRIDEiQ5TBR0.

    Expressioni

    Gene expression databases

    ArrayExpressiQ5TBR0.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5TBR0.
    SMRiQ5TBR0. Positions 1-114.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000284783.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    InterProiIPR013785. Aldolase_TIM.
    IPR013132. Neu5Ac_N.
    [Graphical view]
    PfamiPF03102. NeuB. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q5TBR0-1 [UniParc]FASTAAdd to Basket

    « Hide

    EDVNLRVISE YQKLFPDIPI GYSGHETGIA ISVAAVALGA KVLERHITLD    50
    KTWKGSDHSA SLEPGELAEL VRSVRLVERA LGSPTKQLLP CEMACNEKVC 100
    PAGLYSVLLP CVEKG 115
    Length:115
    Mass (Da):12,398
    Last modified:December 21, 2004 - v1
    Checksum:i8BD52D67DCE39AFE
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL137073 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENST00000427646; ENSP00000404642; ENSG00000095380.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL137073 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali Q5TBR0.
    SMRi Q5TBR0. Positions 1-114.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q5TBR0.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000427646 ; ENSP00000404642 ; ENSG00000095380 .

    Organism-specific databases

    HGNCi HGNC:19237. NANS.
    GenAtlasi Search...

    Phylogenomic databases

    HOGENOMi HOG000284783.

    Miscellaneous databases

    ChiTaRSi NANS. human.
    NextBioi 35539880.

    Gene expression databases

    ArrayExpressi Q5TBR0.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    InterProi IPR013785. Aldolase_TIM.
    IPR013132. Neu5Ac_N.
    [Graphical view ]
    Pfami PF03102. NeuB. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "DNA sequence and analysis of human chromosome 9."
      Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L.
      , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.
      Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    3. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiQ5TBR0_HUMAN
    AccessioniPrimary (citable) accession number: Q5TBR0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 21, 2004
    Last sequence update: December 21, 2004
    Last modified: October 1, 2014
    This is version 54 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3