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Protein
Submitted name:

Serine/threonine-protein kinase Nek6

Gene

NEK6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Enzyme and pathway databases

SignaLinkiQ5TBG4

Names & Taxonomyi

Protein namesi
Submitted name:
Serine/threonine-protein kinase Nek6Imported
Gene namesi
Name:NEK6Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

EuPathDBiHostDB:ENSG00000119408.16
HGNCiHGNC:7749 NEK6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000119408

PTM / Processingi

Proteomic databases

MaxQBiQ5TBG4
PeptideAtlasiQ5TBG4
PRIDEiQ5TBG4

Expressioni

Gene expression databases

BgeeiENSG00000119408
ExpressionAtlasiQ5TBG4 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliQ5TBG4
SMRiQ5TBG4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini79 – 194Protein kinaseInterPro annotationAdd BLAST116

Phylogenomic databases

eggNOGiKOG0591 Eukaryota
ENOG410XNQP LUCA
GeneTreeiENSGT00760000118997
HOGENOMiHOG000233029
HOVERGENiHBG105886

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit

Sequencei

Sequence statusi: Fragment.

Q5TBG4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPRREVCWEA AHFRQEEQSL PRPRVRALVR LACRMAGQPG HMPHGGSSNN
60 70 80 90 100
LCHTLGPVHP PDPQRHPNTL SFRCSLADFQ IEKKIGRGQF SEVYKATCLL
110 120 130 140 150
DRKTVALKKV QIFEMMDAKA RQDCVKEIGL LKQLNHPNII KYLDSFIEDN
160 170 180 190
ELNIVLELAD AGDLSQMIKY FKKQKRLIPE RTVWKYFVQL CSAV
Length:194
Mass (Da):22,353
Last modified:February 5, 2008 - v1
Checksum:i2D012E4E83296F90
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei194Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL137846 Genomic DNA No translation available.
AL162724 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000423785; ENSP00000399847; ENSG00000119408
UCSCiuc064vpp.1 human

Similar proteinsi

Entry informationi

Entry nameiQ5TBG4_HUMAN
AccessioniPrimary (citable) accession number: Q5TBG4
Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: March 28, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health