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Q5T9Y4 (Q5T9Y4_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names

Tumor necrosis factor (Ligand) superfamily, member 11, isoform CRA_c EMBL EAX08681.1
Gene names
Name:TNFSF11 EMBL CAI16926.1
ORF Names:hCG_32838 EMBL EAX08681.1, RP11-86N24.2-001 EMBL CAI16926.1
OrganismHomo sapiens (Human) EMBL CAI16926.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length317 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

Ontologies

Gene Ontology (GO)
   Biological processimmune response

Inferred from electronic annotation. Source: InterPro

   Cellular componentmembrane

Inferred from electronic annotation. Source: InterPro

   Molecular functiontumor necrosis factor receptor binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q5T9Y4 [UniParc].

Last modified May 10, 2005. Version 1.
Checksum: 766176446348097F

FASTA31735,478
        10         20         30         40         50         60 
MRRASRDYTK YLRGSEEMGG GPGAPHEGPL HAPPPPAPHQ PPAASRSMFV ALLGLGLGQV 

        70         80         90        100        110        120 
VCSVALFFYF RAQMDPNRIS EDGTHCIYRI LRLHENADFQ DTTLESQDTK LIPDSCRRIK 

       130        140        150        160        170        180 
QAFQGAVQKE LQHIVGSQHI RAEKAMVDGS WLDLAKRSKL EAQPFAHLTI NATDIPSGSH 

       190        200        210        220        230        240 
KVSLSSWYHD RGWAKISNMT FSNGKLIVNQ DGFYYLYANI CFRHHETSGD LATEYLQLMV 

       250        260        270        280        290        300 
YVTKTSIKIP SSHTLMKGGS TKYWSGNSEF HFYSINVGGF FKLRSGEEIS IEVSNPSLLD 

       310 
PDQDATYFGA FKVRDID 

« Hide

References

« Hide 'large scale' references
[1]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Brain EMBL AAI17287.1.
[2]Pelan S.
Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[3]Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. expand/collapse author list , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC117286 mRNA. Translation: AAI17287.1.
BC117288 mRNA. Translation: AAI17289.1.
AL139382 Genomic DNA. Translation: CAI16926.1.
CH471075 Genomic DNA. Translation: EAX08681.1.
IPIIPI00023732.
RefSeqNP_003692.1. NM_003701.3.
UniGeneHs.333791.

3D structure databases

ProteinModelPortalQ5T9Y4.
SMRQ5T9Y4. Positions 162-317.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ5T9Y4.

Proteomic databases

PRIDEQ5T9Y4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID8600.
KEGGhsa:8600.

Organism-specific databases

CTD8600.

Phylogenomic databases

GeneTreeENSGT00530000063443.
HOVERGENHBG054257.
OMAGKLIVNQ.
PhylomeDBQ5T9Y4.

Gene expression databases

ArrayExpressQ5T9Y4.
BgeeQ5T9Y4.

Family and domain databases

InterProIPR006052. TNF.
IPR017355. TNF_ligand_10/11.
IPR008983. Tumour_necrosis_fac-like.
[Graphical view]
Gene3DG3DSA:2.60.120.40. Tumour_necrosis_fac-like. 1 hit.
KOK05473.
PfamPF00229. TNF. 1 hit.
[Graphical view]
PIRSFPIRSF038013. TNF10_TNF11. 1 hit.
SMARTSM00207. TNF. 1 hit.
[Graphical view]
SUPFAMSSF49842. TNF_like. 1 hit.
PROSITEPS50049. TNF_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio32221.

Entry information

Entry nameQ5T9Y4_HUMAN
AccessionPrimary (citable) accession number: Q5T9Y4
Entry history
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: January 25, 2012
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.