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Protein
Submitted name:

Monocarboxylate transporter 1

Gene

SLC16A1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Monocarboxylate transporter 1Imported
Gene namesi
Name:SLC16A1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000155380.11
HGNCiHGNC:10922 SLC16A1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei17 – 36HelicalSequence analysisAdd BLAST20
Transmembranei87 – 105HelicalSequence analysisAdd BLAST19
Transmembranei111 – 132HelicalSequence analysisAdd BLAST22
Transmembranei144 – 164HelicalSequence analysisAdd BLAST21
Transmembranei176 – 195HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000155380

Expressioni

Gene expression databases

BgeeiENSG00000155380

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini19 – 215MFSInterPro annotationAdd BLAST197

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG2504 Eukaryota
COG0477 LUCA
GeneTreeiENSGT00760000118926
HOGENOMiHOG000280688
HOVERGENiHBG006384

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR030757 MCT1
IPR011701 MFS
IPR020846 MFS_dom
IPR036259 MFS_trans_sf
PANTHERiPTHR11360:SF24 PTHR11360:SF24, 1 hit
PfamiView protein in Pfam
PF07690 MFS_1, 1 hit
SUPFAMiSSF103473 SSF103473, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit

Sequencei

Sequence statusi: Fragment.

Q5T8R4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPPAVGGPVG YTPPDGGWGW AVVIGAFISI GFSYAFPKSI TVFFKEIEGI
60 70 80 90 100
FHATTSEVSW ISSIMLAVMY GGGPISSILV NKYGSRIVMI VGGCLSGCGL
110 120 130 140 150
IAASFCNTVQ QLYVCIGVIG GLGLAFNLNP ALTMIGKYFY KRRPLANGLA
160 170 180 190 200
MAGSPVFLCT LAPLNQVFFG IFGWRGSFLI LGGLLLNCCV AGALMRPIGP
210
KPTKAGKDKS KASLE
Length:215
Mass (Da):22,515
Last modified:December 21, 2004 - v1
Checksum:i9B2BB751AFB868BC
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei215Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL158844 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000429288; ENSP00000397106; ENSG00000155380
ENST00000626371; ENSP00000485854; ENSG00000281917
UCSCiuc057jmz.1 human

Similar proteinsi

Entry informationi

Entry nameiQ5T8R4_HUMAN
AccessioniPrimary (citable) accession number: Q5T8R4
Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: May 23, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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