Q5T8P6 (RBM26_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
RNA-binding protein 26

Alternative name(s):
CTCL tumor antigen se70-2
RNA-binding motif protein 26

Gene names

Name:	RBM26
Synonyms:	C13orf10
ORF Names:	PRO1777

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	1007 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Contains 1 C3H1-type zinc finger. Contains 2 RRM (RNA recognition motif) domains.

Sequence caution

The sequence AAG34912.1 differs from that shown. Reason: Erroneous initiation. The sequence BAB14933.1 differs from that shown. Reason: Erroneous initiation. The sequence BAB55125.1 differs from that shown. Reason: Erroneous initiation. The sequence CAI12921.2 differs from that shown. Reason: Erroneous gene model prediction. The sequence CAI95136.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Coiled coil Repeat Zinc-finger
Ligand	Metal-binding RNA-binding Zinc
PTM	Acetylation Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	mRNA processing Inferred from electronic annotation. Source: InterPro negative regulation of phosphatase activity Inferred from direct assay PubMed 19389623. Source: UniProtKB
Molecular_function	RNA binding Inferred from electronic annotation. Source: UniProtKB-KW nucleotide binding Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Alternative products

This entry describes 6 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q5T8P6-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q5T8P6-2)

The sequence of this isoform differs from the canonical sequence as follows:
     663-686: Missing.

Isoform 3 (identifier: Q5T8P6-3)

The sequence of this isoform differs from the canonical sequence as follows:
     619-621: Missing.
     663-686: Missing.

Note: No experimental confirmation available.

Isoform 4 (identifier: Q5T8P6-4)

The sequence of this isoform differs from the canonical sequence as follows:
     1-446: Missing.
     619-621: Missing.

Note: No experimental confirmation available.

Isoform 5 (identifier: Q5T8P6-5)

The sequence of this isoform differs from the canonical sequence as follows:
     1-446: Missing.
     619-621: Missing.
     663-686: Missing.

Note: No experimental confirmation available.

Isoform 6 (identifier: Q5T8P6-6)

The sequence of this isoform differs from the canonical sequence as follows:
     110-120: ITKEEEREKKF → VTICVNTLQVI
     121-1007: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1007	1007	RNA-binding protein 26		PRO_0000273376
Regions
	Domain	532 – 606	75	RRM 1
	Domain	891 – 960	70	RRM 2
	Zinc finger	288 – 316	29	C3H1-type
	Coiled coil	719 – 795	77	Potential
	Coiled coil	823 – 847	25	Potential
	Compositional bias	134 – 213	80	Arg-rich
	Compositional bias	326 – 420	95	Pro-rich
Amino acid modifications
	Modified residue	127	1	Phosphoserine Ref.7 Ref.9 Ref.12 Ref.14
	Modified residue	510	1	N6-acetyllysine Ref.11
	Modified residue	518	1	Phosphoserine Ref.10
	Modified residue	616	1	Phosphoserine Ref.8 Ref.10
Natural variations
	Alternative sequence	1 – 446	446	Missing in isoform 4 and isoform 5.		VSP_022528
	Alternative sequence	110 – 120	11	ITKEEEREKKF → VTICVNTLQVI in isoform 6.		VSP_022529
	Alternative sequence	121 – 1007	887	Missing in isoform 6.		VSP_022530
	Alternative sequence	619 – 621	3	Missing in isoform 3, isoform 4 and isoform 5.		VSP_022531
	Alternative sequence	663 – 686	24	Missing in isoform 2, isoform 3 and isoform 5.		VSP_022532
	Natural variant	718	1	V → D. Corresponds to variant rs10767 [ dbSNP | Ensembl ].		VAR_030137
Experimental info
	Sequence conflict	12	1	A → T in CAI56708. Ref.5
	Sequence conflict	66	1	Q → H in CAI56708. Ref.5
	Sequence conflict	426	1	D → A in CAI56708. Ref.5
	Sequence conflict	709	1	K → E in BAB55046. Ref.1
	Sequence conflict	900	1	E → G in BAB55046. Ref.1
	Sequence conflict	900	1	E → G in BAB55125. Ref.1
	Sequence conflict	959	1	K → E in BAB14933. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified January 23, 2007. Version 3. Checksum: DCA34DF4A9A42045	FASTA	1,007	113,597
	10 20 30 40 50 60 MVSKMIIENF EALKSWLSKT LEPICDADPS ALAKYVLALV KKDKSEKELK ALCIDQLDVF 70 80 90 100 110 120 LQKETQIFVE KLFDAVNTKS YLPPPEQPSS GSLKVEFFPH QEKDIKKEEI TKEEEREKKF 130 140 150 160 170 180 SRRLNHSPPQ SSSRYRENRS RDERKKDDRS RKRDYDRNPP RRDSYRDRYN RRRGRSRSYS 190 200 210 220 230 240 RSRSRSWSKE RLRERDRDRS RTRSRSRTRS RERDLVKPKY DLDRTDPLEN NYTPVSSVPS 250 260 270 280 290 300 ISSGHYPVPT LSSTITVIAP THHGNNTTES WSEFHEDQVD HNSYVRPPMP KKRCRDYDEK 310 320 330 340 350 360 GFCMRGDMCP FDHGSDPVVV EDVNLPGMLP FPAQPPVVEG PPPPGLPPPP PILTPPPVNL 370 380 390 400 410 420 RPPVPPPGPL PPSLPPVTGP PPPLPPLQPS GMDAPPNSAT SSVPTVVTTG IHHQPPPAPP 430 440 450 460 470 480 SLFTADTYDT DGYNPEAPSI TNTSRPMYRH RVHAQRPNLI GLTSGDMDLP PREKPPNKSS 490 500 510 520 530 540 MRIVVDSESR KRTIGSGEPG VPTKKTWFDK PNFNRTNSPG FQKKVQFGNE NTKLELRKVP 550 560 570 580 590 600 PELNNISKLN EHFSRFGTLV NLQVAYNGDP EGALIQFATY EEAKKAISST EAVLNNRFIK 610 620 630 640 650 660 VYWHREGSTQ QLQTTSPKVM QPLVQQPILP VVKQSVKERL GPVPSSTIEP AEAQSASSDL 670 680 690 700 710 720 PQNVTKLSVK DRLGFVSKPS VSATEKVLST STGLTKTVYN PAALKAAQKT LLVSTSAVDN 730 740 750 760 770 780 NEAQKKKQEA LKLQQDVRKR KQEILEKHIE TQKMLISKLE KNKTMKSEDK AEIMKTLEVL 790 800 810 820 830 840 TKNITKLKDE VKAASPGRCL PKSIKTKTQM QKELLDTELD LYKKMQAGEE VTELRRKYTE 850 860 870 880 890 900 LQLEAAKRGI LSSGRGRGIH SRGRGAVHGR GRGRGRGRGV PGHAVVDHRP RALEISAFTE 910 920 930 940 950 960 SDREDLLPHF AQYGEIEDCQ IDDSSLHAVI TFKTRAEAEA AAVHGARFKG QDLKLAWNKP 970 980 990 1000 VTNISAVETE EVEPDEEEFQ EESLVDDSLL QDDDEEEEDN ESRSWRR
	Isoform 2 [UniParc]. Checksum: DB5E498EF00A14E9	FASTA	983	111,024
	10 20 30 40 50 60 MVSKMIIENF EALKSWLSKT LEPICDADPS ALAKYVLALV KKDKSEKELK ALCIDQLDVF 70 80 90 100 110 120 LQKETQIFVE KLFDAVNTKS YLPPPEQPSS GSLKVEFFPH QEKDIKKEEI TKEEEREKKF 130 140 150 160 170 180 SRRLNHSPPQ SSSRYRENRS RDERKKDDRS RKRDYDRNPP RRDSYRDRYN RRRGRSRSYS 190 200 210 220 230 240 RSRSRSWSKE RLRERDRDRS RTRSRSRTRS RERDLVKPKY DLDRTDPLEN NYTPVSSVPS 250 260 270 280 290 300 ISSGHYPVPT LSSTITVIAP THHGNNTTES WSEFHEDQVD HNSYVRPPMP KKRCRDYDEK 310 320 330 340 350 360 GFCMRGDMCP FDHGSDPVVV EDVNLPGMLP FPAQPPVVEG PPPPGLPPPP PILTPPPVNL 370 380 390 400 410 420 RPPVPPPGPL PPSLPPVTGP PPPLPPLQPS GMDAPPNSAT SSVPTVVTTG IHHQPPPAPP 430 440 450 460 470 480 SLFTADTYDT DGYNPEAPSI TNTSRPMYRH RVHAQRPNLI GLTSGDMDLP PREKPPNKSS 490 500 510 520 530 540 MRIVVDSESR KRTIGSGEPG VPTKKTWFDK PNFNRTNSPG FQKKVQFGNE NTKLELRKVP 550 560 570 580 590 600 PELNNISKLN EHFSRFGTLV NLQVAYNGDP EGALIQFATY EEAKKAISST EAVLNNRFIK 610 620 630 640 650 660 VYWHREGSTQ QLQTTSPKVM QPLVQQPILP VVKQSVKERL GPVPSSTIEP AEAQSASSDL 670 680 690 700 710 720 PQVLSTSTGL TKTVYNPAAL KAAQKTLLVS TSAVDNNEAQ KKKQEALKLQ QDVRKRKQEI 730 740 750 760 770 780 LEKHIETQKM LISKLEKNKT MKSEDKAEIM KTLEVLTKNI TKLKDEVKAA SPGRCLPKSI 790 800 810 820 830 840 KTKTQMQKEL LDTELDLYKK MQAGEEVTEL RRKYTELQLE AAKRGILSSG RGRGIHSRGR 850 860 870 880 890 900 GAVHGRGRGR GRGRGVPGHA VVDHRPRALE ISAFTESDRE DLLPHFAQYG EIEDCQIDDS 910 920 930 940 950 960 SLHAVITFKT RAEAEAAAVH GARFKGQDLK LAWNKPVTNI SAVETEEVEP DEEEFQEESL 970 980 VDDSLLQDDD EEEEDNESRS WRR
	Isoform 3 [UniParc]. Checksum: 6810866351CFDEF0	FASTA	980	110,666
	10 20 30 40 50 60 MVSKMIIENF EALKSWLSKT LEPICDADPS ALAKYVLALV KKDKSEKELK ALCIDQLDVF 70 80 90 100 110 120 LQKETQIFVE KLFDAVNTKS YLPPPEQPSS GSLKVEFFPH QEKDIKKEEI TKEEEREKKF 130 140 150 160 170 180 SRRLNHSPPQ SSSRYRENRS RDERKKDDRS RKRDYDRNPP RRDSYRDRYN RRRGRSRSYS 190 200 210 220 230 240 RSRSRSWSKE RLRERDRDRS RTRSRSRTRS RERDLVKPKY DLDRTDPLEN NYTPVSSVPS 250 260 270 280 290 300 ISSGHYPVPT LSSTITVIAP THHGNNTTES WSEFHEDQVD HNSYVRPPMP KKRCRDYDEK 310 320 330 340 350 360 GFCMRGDMCP FDHGSDPVVV EDVNLPGMLP FPAQPPVVEG PPPPGLPPPP PILTPPPVNL 370 380 390 400 410 420 RPPVPPPGPL PPSLPPVTGP PPPLPPLQPS GMDAPPNSAT SSVPTVVTTG IHHQPPPAPP 430 440 450 460 470 480 SLFTADTYDT DGYNPEAPSI TNTSRPMYRH RVHAQRPNLI GLTSGDMDLP PREKPPNKSS 490 500 510 520 530 540 MRIVVDSESR KRTIGSGEPG VPTKKTWFDK PNFNRTNSPG FQKKVQFGNE NTKLELRKVP 550 560 570 580 590 600 PELNNISKLN EHFSRFGTLV NLQVAYNGDP EGALIQFATY EEAKKAISST EAVLNNRFIK 610 620 630 640 650 660 VYWHREGSTQ QLQTTSPKPL VQQPILPVVK QSVKERLGPV PSSTIEPAEA QSASSDLPQV 670 680 690 700 710 720 LSTSTGLTKT VYNPAALKAA QKTLLVSTSA VDNNEAQKKK QEALKLQQDV RKRKQEILEK 730 740 750 760 770 780 HIETQKMLIS KLEKNKTMKS EDKAEIMKTL EVLTKNITKL KDEVKAASPG RCLPKSIKTK 790 800 810 820 830 840 TQMQKELLDT ELDLYKKMQA GEEVTELRRK YTELQLEAAK RGILSSGRGR GIHSRGRGAV 850 860 870 880 890 900 HGRGRGRGRG RGVPGHAVVD HRPRALEISA FTESDREDLL PHFAQYGEIE DCQIDDSSLH 910 920 930 940 950 960 AVITFKTRAE AEAAAVHGAR FKGQDLKLAW NKPVTNISAV ETEEVEPDEE EFQEESLVDD 970 980 SLLQDDDEEE EDNESRSWRR
	Isoform 4 [UniParc]. Checksum: C408F59C293D82EB	FASTA	558	62,580
	10 20 30 40 50 60 MYRHRVHAQR PNLIGLTSGD MDLPPREKPP NKSSMRIVVD SESRKRTIGS GEPGVPTKKT 70 80 90 100 110 120 WFDKPNFNRT NSPGFQKKVQ FGNENTKLEL RKVPPELNNI SKLNEHFSRF GTLVNLQVAY 130 140 150 160 170 180 NGDPEGALIQ FATYEEAKKA ISSTEAVLNN RFIKVYWHRE GSTQQLQTTS PKPLVQQPIL 190 200 210 220 230 240 PVVKQSVKER LGPVPSSTIE PAEAQSASSD LPQNVTKLSV KDRLGFVSKP SVSATEKVLS 250 260 270 280 290 300 TSTGLTKTVY NPAALKAAQK TLLVSTSAVD NNEAQKKKQE ALKLQQDVRK RKQEILEKHI 310 320 330 340 350 360 ETQKMLISKL EKNKTMKSED KAEIMKTLEV LTKNITKLKD EVKAASPGRC LPKSIKTKTQ 370 380 390 400 410 420 MQKELLDTEL DLYKKMQAGE EVTELRRKYT ELQLEAAKRG ILSSGRGRGI HSRGRGAVHG 430 440 450 460 470 480 RGRGRGRGRG VPGHAVVDHR PRALEISAFT ESDREDLLPH FAQYGEIEDC QIDDSSLHAV 490 500 510 520 530 540 ITFKTRAEAE AAAVHGARFK GQDLKLAWNK PVTNISAVET EEVEPDEEEF QEESLVDDSL 550 LQDDDEEEED NESRSWRR
	Isoform 5 [UniParc]. Checksum: 26F03191A469E43E	FASTA	534	60,007
	10 20 30 40 50 60 MYRHRVHAQR PNLIGLTSGD MDLPPREKPP NKSSMRIVVD SESRKRTIGS GEPGVPTKKT 70 80 90 100 110 120 WFDKPNFNRT NSPGFQKKVQ FGNENTKLEL RKVPPELNNI SKLNEHFSRF GTLVNLQVAY 130 140 150 160 170 180 NGDPEGALIQ FATYEEAKKA ISSTEAVLNN RFIKVYWHRE GSTQQLQTTS PKPLVQQPIL 190 200 210 220 230 240 PVVKQSVKER LGPVPSSTIE PAEAQSASSD LPQVLSTSTG LTKTVYNPAA LKAAQKTLLV 250 260 270 280 290 300 STSAVDNNEA QKKKQEALKL QQDVRKRKQE ILEKHIETQK MLISKLEKNK TMKSEDKAEI 310 320 330 340 350 360 MKTLEVLTKN ITKLKDEVKA ASPGRCLPKS IKTKTQMQKE LLDTELDLYK KMQAGEEVTE 370 380 390 400 410 420 LRRKYTELQL EAAKRGILSS GRGRGIHSRG RGAVHGRGRG RGRGRGVPGH AVVDHRPRAL 430 440 450 460 470 480 EISAFTESDR EDLLPHFAQY GEIEDCQIDD SSLHAVITFK TRAEAEAAAV HGARFKGQDL 490 500 510 520 530 KLAWNKPVTN ISAVETEEVE PDEEEFQEES LVDDSLLQDD DEEEEDNESR SWRR
	Isoform 6 [UniParc]. Checksum: 5E074B43B4BF4D65	FASTA	120	13,644
	10 20 30 40 50 60 MVSKMIIENF EALKSWLSKT LEPICDADPS ALAKYVLALV KKDKSEKELK ALCIDQLDVF 70 80 90 100 110 120 LQKETQIFVE KLFDAVNTKS YLPPPEQPSS GSLKVEFFPH QEKDIKKEEV TICVNTLQVI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 5). Tissue: Adipose tissue, Embryo, Teratocarcinoma and Testis.
[2]	"Functional prediction of the coding sequences of 121 new genes deduced by analysis of cDNA clones from human fetal liver." Zhang C., Yu Y., Zhang S., Wei H., Zhou G., Ouyang S., Luo L., Bi J., Liu M., He F. Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 6). Tissue: Fetal liver.
[3]	"The DNA sequence and analysis of human chromosome 13." Dunham A., Matthews L.H., Burton J., Ashurst J.L., Howe K.L., Ashcroft K.J., Beare D.M., Burford D.C., Hunt S.E., Griffiths-Jones S., Jones M.C., Keenan S.J., Oliver K., Scott C.E., Ainscough R., Almeida J.P., Ambrose K.D., Andrews D.T. , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Bannerjee R., Barlow K.F., Bates K., Beasley H., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burrill W., Carder C., Carter N.P., Chapman J.C., Clamp M.E., Clark S.Y., Clarke G., Clee C.M., Clegg S.C., Cobley V., Collins J.E., Corby N., Coville G.J., Deloukas P., Dhami P., Dunham I., Dunn M., Earthrowl M.E., Ellington A.G., Faulkner L., Frankish A.G., Frankland J., French L., Garner P., Garnett J., Gilbert J.G.R., Gilson C.J., Ghori J., Grafham D.V., Gribble S.M., Griffiths C., Hall R.E., Hammond S., Harley J.L., Hart E.A., Heath P.D., Howden P.J., Huckle E.J., Hunt P.J., Hunt A.R., Johnson C., Johnson D., Kay M., Kimberley A.M., King A., Laird G.K., Langford C.J., Lawlor S., Leongamornlert D.A., Lloyd D.M., Lloyd C., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., McLaren S.J., McMurray A., Milne S., Moore M.J.F., Nickerson T., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K.M., Rice C.M., Searle S., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Steward C.A., Sycamore N., Tester J., Thomas D.W., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Wilming L., Wray P.W., Wright M.W., Young L., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Beck S., Bentley D.R., Rogers J., Ross M.T. Nature 428:522-528(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2; 3 AND 4). Tissue: Lymph.
[5]	"The full-ORF clone resource of the German cDNA consortium." Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I. BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-911 (ISOFORM 2), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 215-869 (ISOFORM 1). Tissue: Amygdala.
[6]	"Serological detection of cutaneous T-cell lymphoma-associated antigens." Eichmueller S., Usener D., Dummer R., Stein A., Thiel D., Schadendorf D. Proc. Natl. Acad. Sci. U.S.A. 98:629-634(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 703-1007. Tissue: Testis.
[7]	"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M. Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-127, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[8]	"A probability-based approach for high-throughput protein phosphorylation analysis and site localization." Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P. Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-616, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[9]	"Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis." Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D., Yates J.R. III J. Proteome Res. 7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-127, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[10]	"A quantitative atlas of mitotic phosphorylation." Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-518 AND SER-616, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[11]	"Lysine acetylation targets protein complexes and co-regulates major cellular functions." Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., Olsen J.V., Mann M. Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract] Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-510, MASS SPECTROMETRY.
[12]	"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis." Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M. Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-127, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[13]	"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[14]	"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation." Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B. Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-127, MASS SPECTROMETRY.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK024610 mRNA. Translation: BAB14933.1. Different initiation. AK027339 mRNA. Translation: BAB55046.1. AK027456 mRNA. Translation: BAB55125.1. Different initiation. AK302871 mRNA. Translation: BAG64052.1. AF116667 mRNA. Translation: AAF71087.1. AL159974, AL139006 Genomic DNA. Translation: CAI12921.2. Sequence problems. AL159974, AL139006 Genomic DNA. Translation: CAI12923.3. AL139006, AL159974 Genomic DNA. Translation: CAI95136.1. Sequence problems. AL139006, AL159974 Genomic DNA. Translation: CAI95137.2. BC041655 mRNA. Translation: AAH41655.1. BC111697 mRNA. Translation: AAI11698.1. BC111739 mRNA. Translation: AAI11740.1. AL834343 mRNA. Translation: CAD39009.3. BX648672 mRNA. Translation: CAI56708.1. AF273052 mRNA. Translation: AAG34912.1. Different initiation.
IPI	IPI00032188. IPI00166555. IPI00329545. IPI00646837. IPI00795335. IPI00827541.
RefSeq	NP_071401.3. NM_022118.3.
UniGene	Hs.558528.
3D structure databases
ProteinModelPortal	Q5T8P6.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q5T8P6. 3 interactions.
PTM databases
PhosphoSite	Q5T8P6.
Polymorphism databases
DMDM	124021002.
Proteomic databases
PaxDb	Q5T8P6.
PRIDE	Q5T8P6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000267229; ENSP00000267229; ENSG00000139746. ENST00000327303; ENSP00000327080; ENSG00000139746. ENST00000438724; ENSP00000390222; ENSG00000139746. ENST00000438737; ENSP00000387531; ENSG00000139746.
GeneID	64062.
KEGG	hsa:64062.
UCSC	uc001vkx.2. human. uc001vky.2. human. uc001vla.2. human. uc001vlc.1. human.
Organism-specific databases
CTD	64062.
GeneCards	GC13M079888.
HGNC	HGNC:20327. RBM26.
HPA	HPA040252.
neXtProt	NX_Q5T8P6.
PharmGKB	PA134982324.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG280405.
HOVERGEN	HBG057372.
InParanoid	Q5T8P6.
KO	K13192.
Gene expression databases
ArrayExpress	Q5T8P6.
Bgee	Q5T8P6.
CleanEx	HS_RBM26.
Genevestigator	Q5T8P6.
Family and domain databases
Gene3D	1.20.1390.10. 1 hit. 3.30.70.330. 2 hits.
InterPro	IPR012677. Nucleotide-bd_a/b_plait. IPR002483. PWI_dom. IPR000504. RRM_dom. IPR000571. Znf_CCCH. [Graphical view]
Pfam	PF01480. PWI. 1 hit. [Graphical view]
SMART	SM00360. RRM. 1 hit. SM00356. ZnF_C3H1. 1 hit. [Graphical view]
PROSITE	PS50102. RRM. 2 hits. PS50103. ZF_C3H1. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	RBM26. human.
GenomeRNAi	64062.
NextBio	65822.
PMAP-CutDB	Q5T8P6.

Entry information

Entry name

RBM26_HUMAN

Accession

Primary (citable) accession number: Q5T8P6
Secondary accession number(s): B4DZE0 , Q2NKM2, Q2NKQ2, Q5CZH8, Q5T8P5, Q5T8P8, Q5U5P5, Q5W0G7, Q8N3H5, Q96K92, Q96SZ3, Q9H2F8, Q9H7F9, Q9P1G7

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 23, 2007
Last sequence update:	January 23, 2007
Last modified:	May 1, 2013
This is version 95 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.