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Protein
Submitted name:

Interferon-induced protein with tetratricopeptide repeats 3, isoform CRA_a

Gene

IFIT3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Interferon-induced protein with tetratricopeptide repeats 3, isoform CRA_aImported
Submitted name:
Interferon-induced protein with tetratricopeptide repeats 3, isoform CRA_bImported
Submitted name:
cDNA FLJ75638, highly similar to Homo sapiens interferon-induced protein with tetratricopeptide repeats 3 (IFIT3), mRNAImported
Gene namesi
Name:IFIT3Imported
ORF Names:hCG_24570Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA29651.

Expressioni

Gene expression databases

BgeeiENSG00000119917.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000360876.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini136 – 274TPR_REGIONInterPro annotationAdd BLAST139

Phylogenomic databases

eggNOGiKOG1124. Eukaryota.
COG0457. LUCA.
HOVERGENiHBG066330.
OMAiCCYKAKV.
OrthoDBiEOG091G06GX.

Family and domain databases

Gene3Di1.25.40.10. 2 hits.
InterProiIPR024122. Interferon-induced_IFIT3.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR019734. TPR_repeat.
[Graphical view]
PANTHERiPTHR10271:SF3. PTHR10271:SF3. 1 hit.
PfamiPF13176. TPR_7. 1 hit.
PF13181. TPR_8. 2 hits.
[Graphical view]
SMARTiSM00028. TPR. 5 hits.
[Graphical view]
SUPFAMiSSF48452. SSF48452. 3 hits.
PROSITEiPS50005. TPR. 5 hits.
PS50293. TPR_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5T765-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEVTKNSLE KILPQLKCHF TWNLFKEDSV SRDLEDRVCN QIEFLNTEFK
60 70 80 90 100
ATMYNLLAYI KHLDGNNEAA LECLRQAEEL IQQEHADQAE IRSLVTWGNY
110 120 130 140 150
AWVYYHLGRL SDAQIYVDKV KQTCKKFSNP YSIEYSELDC EEGWTQLKCG
160 170 180 190 200
RNERAKVCFE KALEEKPNNP EFSSGLAIAM YHLDNHPEKQ FSTDVLKQAI
210 220 230 240 250
ELSPDNQYVK VLLGLKLQKM NKEAEGEQFV EEALEKSPCQ TDVLRSAAKF
260 270 280 290 300
YRRKGDLDKA IELFQRVLES TPNNGYLYHQ IGCCYKAKVR QMQNTGESEA
310 320 330 340 350
SGNKEMIEAL KQYAMDYSNK ALEKGLNPLN AYSDLAEFLE TECYQTPFNK
360 370 380 390 400
EVPDAEKQQS HQRYCNLQKY NGKSEDTAVQ HGLEGLSISK KSTDKEEIKD
410 420 430 440 450
QPQNVSENLL PQNAPNYWYL QGLIHKQNGD LLQAAKCYEK ELGRLLRDAP
460 470 480 490
SGIGSIFLSA SELEDGSEEM GQGAVSSSPR ELLSNSEQLN
Length:490
Mass (Da):55,985
Last modified:May 10, 2005 - v1
Checksum:iB9F042D4DF7151D2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK290427 mRNA. Translation: BAF83116.1.
CH471066 Genomic DNA. Translation: EAW50143.1.
CH471066 Genomic DNA. Translation: EAW50144.1.
RefSeqiNP_001026853.1. NM_001031683.3.
NP_001540.2. NM_001549.5.
UniGeneiHs.47338.
Hs.744072.

Genome annotation databases

GeneIDi3437.
KEGGihsa:3437.
UCSCiuc001kgf.5. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK290427 mRNA. Translation: BAF83116.1.
CH471066 Genomic DNA. Translation: EAW50143.1.
CH471066 Genomic DNA. Translation: EAW50144.1.
RefSeqiNP_001026853.1. NM_001031683.3.
NP_001540.2. NM_001549.5.
UniGeneiHs.47338.
Hs.744072.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000360876.

Protocols and materials databases

DNASUi3437.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi3437.
KEGGihsa:3437.
UCSCiuc001kgf.5. human.

Organism-specific databases

CTDi3437.
PharmGKBiPA29651.

Phylogenomic databases

eggNOGiKOG1124. Eukaryota.
COG0457. LUCA.
HOVERGENiHBG066330.
OMAiCCYKAKV.
OrthoDBiEOG091G06GX.

Miscellaneous databases

GenomeRNAii3437.

Gene expression databases

BgeeiENSG00000119917.

Family and domain databases

Gene3Di1.25.40.10. 2 hits.
InterProiIPR024122. Interferon-induced_IFIT3.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR019734. TPR_repeat.
[Graphical view]
PANTHERiPTHR10271:SF3. PTHR10271:SF3. 1 hit.
PfamiPF13176. TPR_7. 1 hit.
PF13181. TPR_8. 2 hits.
[Graphical view]
SMARTiSM00028. TPR. 5 hits.
[Graphical view]
SUPFAMiSSF48452. SSF48452. 3 hits.
PROSITEiPS50005. TPR. 5 hits.
PS50293. TPR_REGION. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5T765_HUMAN
AccessioniPrimary (citable) accession number: Q5T765
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: November 2, 2016
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.