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Protein
Submitted name:

Interferon-induced protein with tetratricopeptide repeats 3, isoform CRA_a

Gene

IFIT3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Interferon-induced protein with tetratricopeptide repeats 3, isoform CRA_aImported
Submitted name:
Interferon-induced protein with tetratricopeptide repeats 3, isoform CRA_bImported
Submitted name:
cDNA FLJ75638, highly similar to Homo sapiens interferon-induced protein with tetratricopeptide repeats 3 (IFIT3), mRNAImported
Gene namesi
Name:IFIT3Imported
ORF Names:hCG_24570Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000119917.13

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA29651

Expressioni

Gene expression databases

BgeeiENSG00000119917

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati51 – 84TPRPROSITE-ProRule annotationAdd BLAST34
Domaini136 – 274TPR_REGIONInterPro annotationAdd BLAST139
Repeati136 – 169TPRPROSITE-ProRule annotationAdd BLAST34
Repeati207 – 240TPRPROSITE-ProRule annotationAdd BLAST34
Repeati241 – 274TPRPROSITE-ProRule annotationAdd BLAST34
Repeati415 – 448TPRPROSITE-ProRule annotationAdd BLAST34

Keywords - Domaini

TPR repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1124 Eukaryota
COG0457 LUCA
HOVERGENiHBG066330
OMAiNGYLYHQ
OrthoDBiEOG091G06GX

Family and domain databases

Gene3Di1.25.40.10, 3 hits
InterProiView protein in InterPro
IPR024122 Interferon-induced_IFIT3
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat
PANTHERiPTHR10271:SF3 PTHR10271:SF3, 1 hit
PfamiView protein in Pfam
PF13176 TPR_7, 1 hit
PF13181 TPR_8, 2 hits
SMARTiView protein in SMART
SM00028 TPR, 5 hits
SUPFAMiSSF48452 SSF48452, 3 hits
PROSITEiView protein in PROSITE
PS50005 TPR, 5 hits
PS50293 TPR_REGION, 1 hit

Sequencei

Sequence statusi: Complete.

Q5T765-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEVTKNSLE KILPQLKCHF TWNLFKEDSV SRDLEDRVCN QIEFLNTEFK
60 70 80 90 100
ATMYNLLAYI KHLDGNNEAA LECLRQAEEL IQQEHADQAE IRSLVTWGNY
110 120 130 140 150
AWVYYHLGRL SDAQIYVDKV KQTCKKFSNP YSIEYSELDC EEGWTQLKCG
160 170 180 190 200
RNERAKVCFE KALEEKPNNP EFSSGLAIAM YHLDNHPEKQ FSTDVLKQAI
210 220 230 240 250
ELSPDNQYVK VLLGLKLQKM NKEAEGEQFV EEALEKSPCQ TDVLRSAAKF
260 270 280 290 300
YRRKGDLDKA IELFQRVLES TPNNGYLYHQ IGCCYKAKVR QMQNTGESEA
310 320 330 340 350
SGNKEMIEAL KQYAMDYSNK ALEKGLNPLN AYSDLAEFLE TECYQTPFNK
360 370 380 390 400
EVPDAEKQQS HQRYCNLQKY NGKSEDTAVQ HGLEGLSISK KSTDKEEIKD
410 420 430 440 450
QPQNVSENLL PQNAPNYWYL QGLIHKQNGD LLQAAKCYEK ELGRLLRDAP
460 470 480 490
SGIGSIFLSA SELEDGSEEM GQGAVSSSPR ELLSNSEQLN
Length:490
Mass (Da):55,985
Last modified:May 10, 2005 - v1
Checksum:iB9F042D4DF7151D2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK290427 mRNA Translation: BAF83116.1
CH471066 Genomic DNA Translation: EAW50143.1
CH471066 Genomic DNA Translation: EAW50144.1
RefSeqiNP_001026853.1, NM_001031683.3
NP_001540.2, NM_001549.5
UniGeneiHs.47338
Hs.744072

Genome annotation databases

GeneIDi3437
KEGGihsa:3437
UCSCiuc001kgf.5 human

Similar proteinsi

Entry informationi

Entry nameiQ5T765_HUMAN
AccessioniPrimary (citable) accession number: Q5T765
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: March 28, 2018
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
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Main funding by: National Institutes of Health