Q5T6V5 (CI064_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
UPF0553 protein C9orf64

Gene names

Name:

C9orf64

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	341 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities	Belongs to the UPF0553 family.
Sequence caution	The sequence BAC03538.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Technical term	Complete proteome Direct protein sequencing Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 341	341	UPF0553 protein C9orf64		PRO_0000089700
Experimental info
	Sequence conflict	324	1	H → Y in BAC03538. Ref.5

Sequences

	Sequence		Length	Mass (Da)
	Q5T6V5 [UniParc]. Last modified December 21, 2004. Version 1. Checksum: 50AF5A7D7197D7B2	FASTA	341	39,029
	10 20 30 40 50 60 MDGLLNPRES SKFIAENSRD VFIDSGGVRR VAELLLAKAA GPELRVEGWK ALHELNPRAA 70 80 90 100 110 120 DEAAVNWVFV TDTLNFSFWS EQDEHKCVVR YRGKTYSGYW SLCAAVNRAL DEGIPITSAS 130 140 150 160 170 180 YYATVTLDQV RNILRSDTDV SMPLVEERHR ILNETGKILL EKFGGSFLNC VRESENSAQK 190 200 210 220 230 240 LMHLVVESFP SYRDVTLFEG KRVSFYKRAQ ILVADTWSVL EGKGDGCFKD ISSITMFADY 250 260 270 280 290 300 RLPQVLAHLG ALKYSDDLLK KLLKGEMLSY GDRQEVEIRG CSLWCVELIR DCLLELIEQK 310 320 330 340 GEKPNGEINS ILLDYYLWDY AHDHREDMKG IPFHRIRCIY Y

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"DNA sequence and analysis of human chromosome 9." Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L. , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I. Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Brain and Placenta.
[4]	Bienvenut W.V., Glen H., Frame M.C. Submitted (MAR-2008) to UniProtKB Cited for: PROTEIN SEQUENCE OF 31-38; 136-148 AND 163-172, MASS SPECTROMETRY. Tissue: Osteosarcoma.
[5]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 83-341. Tissue: Amygdala.
[6]	"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL354733 Genomic DNA. Translation: CAI16017.1. CH471089 Genomic DNA. Translation: EAW62673.1. BC137461 mRNA. Translation: AAI37462.1. BC137462 mRNA. Translation: AAI37463.1. BC004407 mRNA. No translation available. AK090882 mRNA. Translation: BAC03538.1. Different initiation.
IPI	IPI00170972.
RefSeq	NP_115683.3. NM_032307.3.
UniGene	Hs.208914.
3D structure databases
ProteinModelPortal	Q5T6V5.
ModBase	Search...
Protein-protein interaction databases
STRING	9606.ENSP00000365522.
PTM databases
PhosphoSite	Q5T6V5.
Polymorphism databases
DMDM	73620030.
Proteomic databases
PaxDb	Q5T6V5.
PRIDE	Q5T6V5.
Protocols and materials databases
DNASU	84267.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000376344; ENSP00000365522; ENSG00000165118.
GeneID	84267.
KEGG	hsa:84267.
UCSC	uc004anb.3. human.
Organism-specific databases
CTD	84267.
GeneCards	GC09M086553.
HGNC	HGNC:28144. C9orf64.
MIM	611342. gene.
neXtProt	NX_Q5T6V5.
PharmGKB	PA134865965.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG241762.
HOGENOM	HOG000010664.
HOVERGEN	HBG054936.
InParanoid	Q5T6V5.
OMA	WVFVTDT.
OrthoDB	EOG4TQM9H.
Gene expression databases
ArrayExpress	Q5T6V5.
Bgee	Q5T6V5.
CleanEx	HS_C9orf64.
Genevestigator	Q5T6V5.
GermOnline	ENSG00000165118. Homo sapiens.
Family and domain databases
InterPro	IPR019438. DUF2419. [Graphical view]
PANTHER	PTHR21314. PTHR21314. 1 hit.
Pfam	PF10343. DUF2419. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	84267.
NextBio	73816.
SOURCE	Search...

Entry information

Entry name

CI064_HUMAN

Accession

Primary (citable) accession number: Q5T6V5
Secondary accession number(s): B2RPI6, Q8N2B1, Q9BT18

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 16, 2005
Last sequence update:	December 21, 2004
Last modified:	April 3, 2013
This is version 72 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.