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Protein

UPF0553 protein C9orf64

Gene

C9orf64

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0553 protein C9orf64
Gene namesi
Name:C9orf64
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

HGNCiHGNC:28144. C9orf64.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134865965.

Polymorphism and mutation databases

BioMutaiC9orf64.
DMDMi73620030.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 341341UPF0553 protein C9orf64PRO_0000089700Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1 – 11N-acetylmethionineCombined sources

Keywords - PTMi

Acetylation

Proteomic databases

EPDiQ5T6V5.
MaxQBiQ5T6V5.
PaxDbiQ5T6V5.
PeptideAtlasiQ5T6V5.
PRIDEiQ5T6V5.

PTM databases

iPTMnetiQ5T6V5.
PhosphoSiteiQ5T6V5.

Expressioni

Gene expression databases

BgeeiENSG00000165118.
CleanExiHS_C9orf64.
ExpressionAtlasiQ5T6V5. baseline and differential.
GenevisibleiQ5T6V5. HS.

Organism-specific databases

HPAiHPA054903.
HPA057276.

Interactioni

Protein-protein interaction databases

BioGridi123994. 12 interactions.
STRINGi9606.ENSP00000365522.

Structurei

3D structure databases

ProteinModelPortaliQ5T6V5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0553 family.Curated

Phylogenomic databases

eggNOGiKOG2524. Eukaryota.
ENOG410XRIA. LUCA.
GeneTreeiENSGT00390000002374.
HOGENOMiHOG000010664.
HOVERGENiHBG054936.
InParanoidiQ5T6V5.
OMAiNFCFWTP.
OrthoDBiEOG091G0AGM.
PhylomeDBiQ5T6V5.
TreeFamiTF105811.

Family and domain databases

InterProiIPR019438. Q_salvage.
[Graphical view]
PANTHERiPTHR21314. PTHR21314. 1 hit.
PfamiPF10343. Q_salvage. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5T6V5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDGLLNPRES SKFIAENSRD VFIDSGGVRR VAELLLAKAA GPELRVEGWK
60 70 80 90 100
ALHELNPRAA DEAAVNWVFV TDTLNFSFWS EQDEHKCVVR YRGKTYSGYW
110 120 130 140 150
SLCAAVNRAL DEGIPITSAS YYATVTLDQV RNILRSDTDV SMPLVEERHR
160 170 180 190 200
ILNETGKILL EKFGGSFLNC VRESENSAQK LMHLVVESFP SYRDVTLFEG
210 220 230 240 250
KRVSFYKRAQ ILVADTWSVL EGKGDGCFKD ISSITMFADY RLPQVLAHLG
260 270 280 290 300
ALKYSDDLLK KLLKGEMLSY GDRQEVEIRG CSLWCVELIR DCLLELIEQK
310 320 330 340
GEKPNGEINS ILLDYYLWDY AHDHREDMKG IPFHRIRCIY Y
Length:341
Mass (Da):39,029
Last modified:December 21, 2004 - v1
Checksum:i50AF5A7D7197D7B2
GO

Sequence cautioni

The sequence BAC03538 differs from that shown. Reason: Erroneous initiation. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti324 – 3241H → Y in BAC03538 (PubMed:14702039).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL354733 Genomic DNA. Translation: CAI16017.1.
CH471089 Genomic DNA. Translation: EAW62673.1.
BC137461 mRNA. Translation: AAI37462.1.
BC137462 mRNA. Translation: AAI37463.1.
BC004407 mRNA. No translation available.
AK090882 mRNA. Translation: BAC03538.1. Different initiation.
CCDSiCCDS6666.2.
RefSeqiNP_001304926.1. NM_001317997.1.
NP_115683.3. NM_032307.4.
UniGeneiHs.208914.

Genome annotation databases

EnsembliENST00000376344; ENSP00000365522; ENSG00000165118.
GeneIDi84267.
KEGGihsa:84267.
UCSCiuc004anb.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL354733 Genomic DNA. Translation: CAI16017.1.
CH471089 Genomic DNA. Translation: EAW62673.1.
BC137461 mRNA. Translation: AAI37462.1.
BC137462 mRNA. Translation: AAI37463.1.
BC004407 mRNA. No translation available.
AK090882 mRNA. Translation: BAC03538.1. Different initiation.
CCDSiCCDS6666.2.
RefSeqiNP_001304926.1. NM_001317997.1.
NP_115683.3. NM_032307.4.
UniGeneiHs.208914.

3D structure databases

ProteinModelPortaliQ5T6V5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi123994. 12 interactions.
STRINGi9606.ENSP00000365522.

PTM databases

iPTMnetiQ5T6V5.
PhosphoSiteiQ5T6V5.

Polymorphism and mutation databases

BioMutaiC9orf64.
DMDMi73620030.

Proteomic databases

EPDiQ5T6V5.
MaxQBiQ5T6V5.
PaxDbiQ5T6V5.
PeptideAtlasiQ5T6V5.
PRIDEiQ5T6V5.

Protocols and materials databases

DNASUi84267.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000376344; ENSP00000365522; ENSG00000165118.
GeneIDi84267.
KEGGihsa:84267.
UCSCiuc004anb.4. human.

Organism-specific databases

CTDi84267.
GeneCardsiC9orf64.
HGNCiHGNC:28144. C9orf64.
HPAiHPA054903.
HPA057276.
MIMi611342. gene.
neXtProtiNX_Q5T6V5.
PharmGKBiPA134865965.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2524. Eukaryota.
ENOG410XRIA. LUCA.
GeneTreeiENSGT00390000002374.
HOGENOMiHOG000010664.
HOVERGENiHBG054936.
InParanoidiQ5T6V5.
OMAiNFCFWTP.
OrthoDBiEOG091G0AGM.
PhylomeDBiQ5T6V5.
TreeFamiTF105811.

Miscellaneous databases

GeneWikiiC9orf64.
GenomeRNAii84267.
PROiQ5T6V5.
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000165118.
CleanExiHS_C9orf64.
ExpressionAtlasiQ5T6V5. baseline and differential.
GenevisibleiQ5T6V5. HS.

Family and domain databases

InterProiIPR019438. Q_salvage.
[Graphical view]
PANTHERiPTHR21314. PTHR21314. 1 hit.
PfamiPF10343. Q_salvage. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCI064_HUMAN
AccessioniPrimary (citable) accession number: Q5T6V5
Secondary accession number(s): B2RPI6, Q8N2B1, Q9BT18
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 16, 2005
Last sequence update: December 21, 2004
Last modified: September 7, 2016
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families
  4. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.