Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Queuosine salvage protein

Gene

C9orf64

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Involved in salvaging queuosine.1 Publication

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Queuosine salvage protein1 Publication
Gene namesi
Name:C9orf64
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

EuPathDBiHostDB:ENSG00000165118.14.
HGNCiHGNC:28144. C9orf64.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000165118.
PharmGKBiPA134865965.

Polymorphism and mutation databases

BioMutaiC9orf64.
DMDMi73620030.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000897001 – 341Queuosine salvage proteinAdd BLAST341

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1N-acetylmethionineCombined sources1

Keywords - PTMi

Acetylation

Proteomic databases

EPDiQ5T6V5.
MaxQBiQ5T6V5.
PaxDbiQ5T6V5.
PeptideAtlasiQ5T6V5.
PRIDEiQ5T6V5.

PTM databases

iPTMnetiQ5T6V5.
PhosphoSitePlusiQ5T6V5.

Expressioni

Gene expression databases

BgeeiENSG00000165118.
CleanExiHS_C9orf64.
ExpressionAtlasiQ5T6V5. baseline and differential.
GenevisibleiQ5T6V5. HS.

Organism-specific databases

HPAiHPA054903.
HPA066190.

Interactioni

Protein-protein interaction databases

BioGridi123994. 14 interactors.
IntActiQ5T6V5. 1 interactor.
STRINGi9606.ENSP00000365522.

Structurei

3D structure databases

ProteinModelPortaliQ5T6V5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the queuosine salvage protein family.Curated

Phylogenomic databases

eggNOGiKOG2524. Eukaryota.
ENOG410XRIA. LUCA.
GeneTreeiENSGT00390000002374.
HOGENOMiHOG000010664.
HOVERGENiHBG054936.
InParanoidiQ5T6V5.
OMAiLNFCFWT.
OrthoDBiEOG091G0AGM.
PhylomeDBiQ5T6V5.
TreeFamiTF105811.

Family and domain databases

InterProiView protein in InterPro
IPR019438. Q_salvage.
PANTHERiPTHR21314. PTHR21314. 1 hit.
PfamiView protein in Pfam
PF10343. Q_salvage. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5T6V5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDGLLNPRES SKFIAENSRD VFIDSGGVRR VAELLLAKAA GPELRVEGWK
60 70 80 90 100
ALHELNPRAA DEAAVNWVFV TDTLNFSFWS EQDEHKCVVR YRGKTYSGYW
110 120 130 140 150
SLCAAVNRAL DEGIPITSAS YYATVTLDQV RNILRSDTDV SMPLVEERHR
160 170 180 190 200
ILNETGKILL EKFGGSFLNC VRESENSAQK LMHLVVESFP SYRDVTLFEG
210 220 230 240 250
KRVSFYKRAQ ILVADTWSVL EGKGDGCFKD ISSITMFADY RLPQVLAHLG
260 270 280 290 300
ALKYSDDLLK KLLKGEMLSY GDRQEVEIRG CSLWCVELIR DCLLELIEQK
310 320 330 340
GEKPNGEINS ILLDYYLWDY AHDHREDMKG IPFHRIRCIY Y
Length:341
Mass (Da):39,029
Last modified:December 21, 2004 - v1
Checksum:i50AF5A7D7197D7B2
GO

Sequence cautioni

The sequence BAC03538 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti324H → Y in BAC03538 (PubMed:14702039).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL354733 Genomic DNA. No translation available.
CH471089 Genomic DNA. Translation: EAW62673.1.
BC137461 mRNA. Translation: AAI37462.1.
BC137462 mRNA. Translation: AAI37463.1.
BC004407 mRNA. No translation available.
AK090882 mRNA. Translation: BAC03538.1. Different initiation.
CCDSiCCDS6666.2.
RefSeqiNP_001304926.1. NM_001317997.1.
NP_115683.3. NM_032307.4.
UniGeneiHs.208914.

Genome annotation databases

EnsembliENST00000376344; ENSP00000365522; ENSG00000165118.
GeneIDi84267.
KEGGihsa:84267.
UCSCiuc004anb.4. human.

Similar proteinsi

Entry informationi

Entry nameiQSPP_HUMAN
AccessioniPrimary (citable) accession number: Q5T6V5
Secondary accession number(s): B2RPI6, Q8N2B1, Q9BT18
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2005
Last sequence update: December 21, 2004
Last modified: September 27, 2017
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families