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Protein
Submitted name:

High mobility group AT-hook 1

Gene

HMGA1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
High mobility group AT-hook 1Imported
Gene namesi
Name:HMGA1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA35094.

Expressioni

Gene expression databases

ExpressionAtlasiQ5T6U8. baseline and differential.

Interactioni

Protein-protein interaction databases

IntActiQ5T6U8. 1 interaction.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00730000111329.
HOGENOMiHOG000076308.
HOVERGENiHBG097343.
KOiK09282.

Family and domain databases

InterProiIPR017956. AT_hook_DNA-bd_motif.
IPR000116. HMGA.
IPR031079. HMGA1_mammal.
IPR000637. HMGI/Y_DNA-bd_CS.
[Graphical view]
PANTHERiPTHR23341:SF1. PTHR23341:SF1. 1 hit.
PRINTSiPR00929. ATHOOK.
PR00930. HIGHMOBLTYIY.
SMARTiSM00384. AT_hook. 3 hits.
[Graphical view]
PROSITEiPS00354. HMGI_Y. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5T6U8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSESSSKSSQ PLASKQEKDG TEKRGRGRPR KQPPKEPSEV PTPKRPRGRP
60 70 80 90
KGSKNKGAAK TRKTTTTPGR KPRGRPKKLE KEEEEGISQE SSEEEQ
Length:96
Mass (Da):10,679
Last modified:May 10, 2005 - v1
Checksum:iB82DCAA29E6D18FD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC015789 mRNA. Translation: AAH15789.1.
BT006774 mRNA. Translation: AAP35420.1.
RefSeqiNP_001306006.1. NM_001319077.1.
NP_002122.1. NM_002131.3.
NP_665909.1. NM_145902.2.
NP_665910.1. NM_145903.2.
NP_665912.1. NM_145905.2.
UniGeneiHs.518805.
Hs.696527.
Hs.703764.

Genome annotation databases

GeneIDi3159.
KEGGihsa:3159.
UCSCiuc003oiv.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC015789 mRNA. Translation: AAH15789.1.
BT006774 mRNA. Translation: AAP35420.1.
RefSeqiNP_001306006.1. NM_001319077.1.
NP_002122.1. NM_002131.3.
NP_665909.1. NM_145902.2.
NP_665910.1. NM_145903.2.
NP_665912.1. NM_145905.2.
UniGeneiHs.518805.
Hs.696527.
Hs.703764.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ5T6U8. 1 interaction.

Protocols and materials databases

DNASUi3159.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi3159.
KEGGihsa:3159.
UCSCiuc003oiv.4. human.

Organism-specific databases

CTDi3159.
PharmGKBiPA35094.

Phylogenomic databases

GeneTreeiENSGT00730000111329.
HOGENOMiHOG000076308.
HOVERGENiHBG097343.
KOiK09282.

Miscellaneous databases

ChiTaRSiHMGA1. human.
GenomeRNAii3159.
NextBioi12514.

Gene expression databases

ExpressionAtlasiQ5T6U8. baseline and differential.

Family and domain databases

InterProiIPR017956. AT_hook_DNA-bd_motif.
IPR000116. HMGA.
IPR031079. HMGA1_mammal.
IPR000637. HMGI/Y_DNA-bd_CS.
[Graphical view]
PANTHERiPTHR23341:SF1. PTHR23341:SF1. 1 hit.
PRINTSiPR00929. ATHOOK.
PR00930. HIGHMOBLTYIY.
SMARTiSM00384. AT_hook. 3 hits.
[Graphical view]
PROSITEiPS00354. HMGI_Y. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning of human full-length CDSs in BD Creator(TM) System Donor vector."
    Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S., Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y., Phelan M., Farmer A.
    Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: ColonImported.

Entry informationi

Entry nameiQ5T6U8_HUMAN
AccessioniPrimary (citable) accession number: Q5T6U8
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: May 11, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.