##gff-version 3
Q5T6S3	UniProtKB	Chain	1	580	.	.	.	ID=PRO_0000318570;Note=PHD finger protein 19	
Q5T6S3	UniProtKB	Domain	40	93	.	.	.	Note=Tudor	
Q5T6S3	UniProtKB	Zinc finger	96	151	.	.	.	Note=PHD-type 1	
Q5T6S3	UniProtKB	Zinc finger	195	249	.	.	.	Note=PHD-type 2	
Q5T6S3	UniProtKB	Region	74	80	.	.	.	Note=Histone H3K36me3 binding	
Q5T6S3	UniProtKB	Region	347	390	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q5T6S3	UniProtKB	Region	496	521	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q5T6S3	UniProtKB	Region	531	580	.	.	.	Note=Interaction with SUZ12;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:29499137;Dbxref=PMID:29499137	
Q5T6S3	UniProtKB	Region	531	544	.	.	.	Note=Important for PRC2 dimer stability;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:31959557;Dbxref=PMID:31959557	
Q5T6S3	UniProtKB	Site	47	47	.	.	.	Note=Histone H3K36me3 binding	
Q5T6S3	UniProtKB	Site	55	55	.	.	.	Note=Histone H3K36me3 binding	
Q5T6S3	UniProtKB	Modified residue	13	13	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:23186163;Dbxref=PMID:23186163	
Q5T6S3	UniProtKB	Modified residue	187	187	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:23186163;Dbxref=PMID:23186163	
Q5T6S3	UniProtKB	Modified residue	365	365	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:23186163;Dbxref=PMID:23186163	
Q5T6S3	UniProtKB	Modified residue	366	366	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:23186163;Dbxref=PMID:23186163	
Q5T6S3	UniProtKB	Alternative sequence	122	130	.	.	.	ID=VSP_031222;Note=In isoform 3. GYHQQCHIP->VPHPHSGQC;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334	
Q5T6S3	UniProtKB	Alternative sequence	131	580	.	.	.	ID=VSP_031223;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334	
Q5T6S3	UniProtKB	Alternative sequence	155	207	.	.	.	ID=VSP_031224;Note=In isoform 2. RKGGALKKGAIARTLQAVKMVLSYQPEELEWDSPHRTNQQQCYCYCGGPGEWY->RVSLPSSPVPASPASSSGADQRLPSQSLSSKQKGHTWALETDSASATVLGQDL;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334	
Q5T6S3	UniProtKB	Alternative sequence	208	580	.	.	.	ID=VSP_031225;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334	
Q5T6S3	UniProtKB	Mutagenesis	50	50	.	.	.	Note=In muthPhf19%3B abolishes histone H3K36me3-binding and impaired activity of the PRC2 complex and subsequent H3K27me3 methylation. W->A;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:23104054,ECO:0000269|PubMed:23160351;Dbxref=PMID:23104054,PMID:23160351	
Q5T6S3	UniProtKB	Mutagenesis	50	50	.	.	.	Note=Abolishes histone H3K36me3-binding and recruitment of the PRC2 complex and RIOX1%3B when associated with A-56. W->C;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:23104054,ECO:0000269|PubMed:23160351;Dbxref=PMID:23104054,PMID:23160351	
Q5T6S3	UniProtKB	Mutagenesis	56	56	.	.	.	Note=Abolishes histone H3K36me3-binding. Abolishes histone H3K36me3-binding and recruitment of the PRC2 complex and RIOX1%3B when associated with C-50. Y->A;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:23160351,ECO:0000269|PubMed:23273982;Dbxref=PMID:23160351,PMID:23273982	
Q5T6S3	UniProtKB	Mutagenesis	331	332	.	.	.	Note=Impairs chromatin binding as part of the PRC2 complex. KK->AA;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:31959557;Dbxref=PMID:31959557	
Q5T6S3	UniProtKB	Sequence conflict	181	181	.	.	.	Note=E->G;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q5T6S3	UniProtKB	Beta strand	45	49	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6WAU	
Q5T6S3	UniProtKB	Beta strand	55	64	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6WAU	
Q5T6S3	UniProtKB	Turn	65	68	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6WAU	
Q5T6S3	UniProtKB	Beta strand	69	73	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6WAU	
Q5T6S3	UniProtKB	Beta strand	79	83	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6WAU	
Q5T6S3	UniProtKB	Helix	84	86	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6WAU	
Q5T6S3	UniProtKB	Beta strand	87	89	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6WAU	
Q5T6S3	UniProtKB	Helix	531	543	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6NQ3	
Q5T6S3	UniProtKB	Helix	545	551	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6NQ3	
Q5T6S3	UniProtKB	Beta strand	555	563	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6NQ3	
Q5T6S3	UniProtKB	Turn	564	566	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6NQ3	
Q5T6S3	UniProtKB	Beta strand	567	574	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:6NQ3	
Q5T6S3	UniProtKB	Modified residue	166	166	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:18691976;Dbxref=PMID:18691976