Q5T6H7 (Q5T6H7_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Xaa-Pro aminopeptidase 1 Ensembl ENSP00000358697

Gene names

Name:

XPNPEP1 Ensembl ENSP00000358697

Organism

Homo sapiens (Human) [Reference proteome] Ensembl ENSP00000358697

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	552 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSP00000358697

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cellular process Inferred from electronic annotation. Source: InterPro proteolysis Inferred from electronic annotation. Source: Compara
Cellular_component	cytoplasm Inferred from direct assay. Source: HPA cytosol Inferred from electronic annotation. Source: Compara
Molecular_function	hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5T6H7 [UniParc]. Last modified December 21, 2004. Version 1. Checksum: 627539255505E5CE	FASTA	552	62,139
	10 20 30 40 50 60 MWTDGRYFLQ AAKQMDSNWT LMKMGLKDTP TQEDWLVSVL PEGSRVGVDP LIIPTDYWKK 70 80 90 100 110 120 MAKVLRSAGH HLIPVKENLV DKIWTDRPER PCKPLLTLGL DYTGISWKDK VADLRLKMAE 130 140 150 160 170 180 RNVMWFVVTA LDEIAWLFNL RGSDVEHNPV FFSYAIIGLE TIMLFIDGDR IDAPSVKEHL 190 200 210 220 230 240 LLDLGLEAEY RIQVHPYKSI LSELKALCAD LSPREKVWVS DKASYAVSET IPKDHRCCMP 250 260 270 280 290 300 YTPICIAKAV KNSAESEGMR RAHIKDAVAL CELFNWLEKE VPKGGVTEIS AADKAEEFRR 310 320 330 340 350 360 QQADFVDLSF PTISSTGPNG AIIHYAPVPE TNRTLSLDEV YLIDSGAQYK DGTTDVTRTM 370 380 390 400 410 420 HFGTPTAYEK ECFTYVLKGH IAVSAAVFPT GTKGHLLDSF ARSALWDSGL DYLHGTGHGV 430 440 450 460 470 480 GSFLNVHEGP CGISYKTFSD EPLEAGMIVT DEPGYYEDGA FGIRIENVVL VVPVKTKYNF 490 500 510 520 530 540 NNRGSLTFEP LTLVPIQTKM IDVDSLTDKE CDWLNNYHLT CRDVIGKELQ KQGRQEALEW 550 LIRETQPISK QH

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The DNA sequence and comparative analysis of human chromosome 10." Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J. , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J. Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL354951 Genomic DNA. No translation available.
IPI	IPI00645898.
UniGene	Hs.390623.
3D structure databases
ProteinModelPortal	Q5T6H7.
SMR	Q5T6H7. Positions 1-548.
ModBase	Search...
Protein-protein interaction databases
MINT	MINT-1382650.
Proteomic databases
PRIDE	Q5T6H7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000369683; ENSP00000358697; ENSG00000108039.
Organism-specific databases
HGNC	HGNC:12822. XPNPEP1.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	HBG002934.
Gene expression databases
ArrayExpress	Q5T6H7.
Family and domain databases
Gene3D	3.90.230.10. 1 hit.
InterPro	IPR000587. Creatinase. IPR000994. Pept_M24_structural-domain. IPR001131. Peptidase_M24B_aminopep-P_CS. [Graphical view]
Pfam	PF01321. Creatinase_N. 1 hit. PF00557. Peptidase_M24. 1 hit. [Graphical view]
SUPFAM	SSF55920. Peptidase_M24_cat_core. 1 hit.
PROSITE	PS00491. PROLINE_PEPTIDASE. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	XPNPEP1. human.

Entry information

Entry name

Q5T6H7_HUMAN

Accession

Primary (citable) accession number: Q5T6H7

Entry history

Integrated into UniProtKB/TrEMBL:	December 21, 2004
Last sequence update:	December 21, 2004
Last modified:	May 1, 2013
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.