Q5T681 (CJ062_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein C10orf62

Gene names

Name:

C10orf62

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	223 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Coding sequence diversity	Polymorphism
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
MDFI	Q99750	4	EBI-744052,EBI-724076

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 223	223	Uncharacterized protein C10orf62		PRO_0000274241
Regions
	Compositional bias	195 – 223	29	His-rich
Natural variations
	Natural variant	121	1	E → D. Ref.2 Corresponds to variant rs7093840 [ dbSNP | Ensembl ].		VAR_030216

Sequences

	Sequence		Length	Mass (Da)
	Q5T681 [UniParc]. Last modified December 21, 2004. Version 1. Checksum: 85C075F7C2DDEAAE	FASTA	223	25,128
	10 20 30 40 50 60 MLWVQRKRRR KETSECPSDK DKSPESHKAK NESWIKSHFS RLSEEKLALD NNASASGNAT 70 80 90 100 110 120 QTESGSEEVS STVHIETFTT RHGEVGSALH RESFTSRQKT SGPSVIQEIH QESGKAPSTD 130 140 150 160 170 180 EATWAAVAAC TKEIDTQGRH LAHSMLQRAI AYQHSGHLES KDINQEELRA LEEVEMKLQK 190 200 210 220 NFLTQRENTI AGANHTHTFY GHSHHSHHGH PSHQSHSLPN RRH

References

[1]

"The DNA sequence and comparative analysis of human chromosome 10." Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J. , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J. Nature 429:375-381(2004) [PubMed: 15164054] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

[2]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT ASP-121. Tissue: Brain.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL355315 Genomic DNA. Translation: CAI15456.1. BC037252 mRNA. Translation: AAH37252.1.
IPI	IPI00384212.
RefSeq	NP_001009997.2. NM_001009997.2.
UniGene	Hs.662302.
3D structure databases
ProteinModelPortal	Q5T681.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q5T681. 4 interactions.
PTM databases
PhosphoSite	Q5T681.
Proteomic databases
PRIDE	Q5T681.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000370640; ENSP00000359674; ENSG00000203942.
GeneID	414157.
KEGG	hsa:414157.
UCSC	uc001koa.1. human.
Organism-specific databases
CTD	414157.
GeneCards	GC10P099349.
HGNC	HGNC:23294. C10orf62.
HPA	HPA036884.
neXtProt	NX_Q5T681.
PharmGKB	PA134924151.
GenAtlas	Search...
Phylogenomic databases
eggNOG	prNOG07484.
GeneTree	ENSGT00390000015820.
InParanoid	Q5T681.
OMA	SMLQRAT.
OrthoDB	EOG4FXR8N.
Gene expression databases
ArrayExpress	Q5T681.
Bgee	Q5T681.
CleanEx	HS_C10orf62.
Genevestigator	Q5T681.
Family and domain databases
ProtoNet	Search...
Other
NextBio	108420.

Entry information

Entry name

CJ062_HUMAN

Accession

Primary (citable) accession number: Q5T681
Secondary accession number(s): Q49A70, Q8N3Y6

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 6, 2007
Last sequence update:	December 21, 2004
Last modified:	January 25, 2012
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.