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Protein

Uncharacterized protein C10orf62

Gene

C10orf62

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C10orf62
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

HGNCiHGNC:23294. C10orf62.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134924151.

Polymorphism and mutation databases

BioMutaiC10orf62.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 223223Uncharacterized protein C10orf62PRO_0000274241Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei43 – 431PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ5T681.
PRIDEiQ5T681.

PTM databases

iPTMnetiQ5T681.
PhosphoSiteiQ5T681.

Expressioni

Gene expression databases

BgeeiQ5T681.
CleanExiHS_C10orf62.
GenevisibleiQ5T681. HS.

Organism-specific databases

HPAiHPA036884.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
FXR2P511164EBI-744052,EBI-740459
KRT40Q6A1623EBI-744052,EBI-10171697
KRTAP10-9P604113EBI-744052,EBI-10172052
KRTAP5-9P263713EBI-744052,EBI-3958099
MDFIQ997507EBI-744052,EBI-724076

Protein-protein interaction databases

BioGridi135946. 8 interactions.
IntActiQ5T681. 7 interactions.
STRINGi9606.ENSP00000359674.

Structurei

3D structure databases

ProteinModelPortaliQ5T681.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi195 – 22329His-richAdd
BLAST

Phylogenomic databases

eggNOGiENOG410IZEP. Eukaryota.
ENOG41118MP. LUCA.
GeneTreeiENSGT00390000015820.
HOGENOMiHOG000111688.
InParanoidiQ5T681.
OMAiESWIKSH.
OrthoDBiEOG7RJPSX.
PhylomeDBiQ5T681.
TreeFamiTF353569.

Sequencei

Sequence statusi: Complete.

Q5T681-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLWVQRKRRR KETSECPSDK DKSPESHKAK NESWIKSHFS RLSEEKLALD
60 70 80 90 100
NNASASGNAT QTESGSEEVS STVHIETFTT RHGEVGSALH RESFTSRQKT
110 120 130 140 150
SGPSVIQEIH QESGKAPSTD EATWAAVAAC TKEIDTQGRH LAHSMLQRAI
160 170 180 190 200
AYQHSGHLES KDINQEELRA LEEVEMKLQK NFLTQRENTI AGANHTHTFY
210 220
GHSHHSHHGH PSHQSHSLPN RRH
Length:223
Mass (Da):25,128
Last modified:December 21, 2004 - v1
Checksum:i85C075F7C2DDEAAE
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti121 – 1211E → D.1 Publication
Corresponds to variant rs7093840 [ dbSNP | Ensembl ].
VAR_030216

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL355315 Genomic DNA. Translation: CAI15456.1.
BC037252 mRNA. Translation: AAH37252.1.
CCDSiCCDS31261.1.
RefSeqiNP_001009997.2. NM_001009997.2.
UniGeneiHs.662302.

Genome annotation databases

EnsembliENST00000370640; ENSP00000359674; ENSG00000203942.
GeneIDi414157.
KEGGihsa:414157.
UCSCiuc001koa.4. human.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL355315 Genomic DNA. Translation: CAI15456.1.
BC037252 mRNA. Translation: AAH37252.1.
CCDSiCCDS31261.1.
RefSeqiNP_001009997.2. NM_001009997.2.
UniGeneiHs.662302.

3D structure databases

ProteinModelPortaliQ5T681.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi135946. 8 interactions.
IntActiQ5T681. 7 interactions.
STRINGi9606.ENSP00000359674.

PTM databases

iPTMnetiQ5T681.
PhosphoSiteiQ5T681.

Polymorphism and mutation databases

BioMutaiC10orf62.

Proteomic databases

PaxDbiQ5T681.
PRIDEiQ5T681.

Protocols and materials databases

DNASUi414157.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000370640; ENSP00000359674; ENSG00000203942.
GeneIDi414157.
KEGGihsa:414157.
UCSCiuc001koa.4. human.

Organism-specific databases

CTDi414157.
GeneCardsiC10orf62.
HGNCiHGNC:23294. C10orf62.
HPAiHPA036884.
neXtProtiNX_Q5T681.
PharmGKBiPA134924151.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IZEP. Eukaryota.
ENOG41118MP. LUCA.
GeneTreeiENSGT00390000015820.
HOGENOMiHOG000111688.
InParanoidiQ5T681.
OMAiESWIKSH.
OrthoDBiEOG7RJPSX.
PhylomeDBiQ5T681.
TreeFamiTF353569.

Miscellaneous databases

GenomeRNAii414157.
PROiQ5T681.

Gene expression databases

BgeeiQ5T681.
CleanExiHS_C10orf62.
GenevisibleiQ5T681. HS.

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. "The DNA sequence and comparative analysis of human chromosome 10."
    Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J.
    , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.
    Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT ASP-121.
    Tissue: Brain.

Entry informationi

Entry nameiCJ062_HUMAN
AccessioniPrimary (citable) accession number: Q5T681
Secondary accession number(s): Q49A70, Q8N3Y6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: December 21, 2004
Last modified: June 8, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.