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Protein
Submitted name:

Nuclear autoantigenic sperm protein (Histone-binding)

Gene

NASP

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear autoantigenic sperm protein (Histone-binding)Imported
Submitted name:
Nuclear autoantigenic sperm protein (Histone-binding), isoform CRA_aImported
Gene namesi
Name:NASPImported
ORF Names:hCG_40880Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000132780.16.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA31448.

PTM / Processingi

Proteomic databases

MaxQBiQ5T626.

Expressioni

Gene expression databases

BgeeiENSG00000132780.

Interactioni

Protein-protein interaction databases

IntActiQ5T626. 1 interactor.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini43 – 76TPR_REGIONInterPro annotationAdd BLAST34
Repeati43 – 76TPRPROSITE-ProRule annotationAdd BLAST34
Domaini203 – 278TPR_REGIONInterPro annotationAdd BLAST76
Repeati203 – 236TPRPROSITE-ProRule annotationAdd BLAST34
Repeati245 – 278TPRPROSITE-ProRule annotationAdd BLAST34

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili265 – 320Sequence analysisAdd BLAST56

Keywords - Domaini

Coiled coilSequence analysis, TPR repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG4563. Eukaryota.
ENOG4110P5E. LUCA.
HOGENOMiHOG000273906.
HOVERGENiHBG002186.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
InterProiView protein in InterPro
IPR019544. Tetratricopeptide_SHNi-TPR_dom.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom_sf.
IPR019734. TPR_repeat.
PfamiView protein in Pfam
PF10516. SHNi-TPR. 1 hit.
SMARTiView protein in SMART
SM00028. TPR. 3 hits.
SUPFAMiSSF48452. SSF48452. 2 hits.
PROSITEiView protein in PROSITE
PS50005. TPR. 3 hits.
PS50293. TPR_REGION. 2 hits.

Sequencei

Sequence statusi: Complete.

Q5T626-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAMESTATAA VAAELVSADK IEDVPAPSTS ADKVESLDVD SEAKKLLGLG
60 70 80 90 100
QKHLVMGDIP AAVNAFQEAA SLLGKKYGET ANECGEAFFF YGKSLLELAR
110 120 130 140 150
MENGVLGNAL EGVHVEEEEG EKTEDESLVE NNDNIDETEG SEEDDKENDK
160 170 180 190 200
TEEMPNDSVL ENKSLQENEE EEIGNLELAW DMLDLAKIIF KRQETKEAQL
210 220 230 240 250
YAAQAHLKLG EVSVESENYV QAVEEFQSCL NLQEQYLEAH DRLLAETHYQ
260 270 280 290 300
LGLAYGYNSQ YDEAVAQFSK SIEVIENRMA VLNEQVKEAE GSSAEYKKEI
310 320 330 340 350
EELKELLPEI REKIEDAKES QRSGNVAELA LKATLVESST SGFTPGGGGS
360 370 380 390 400
SVSMIASRKP TDGASSSNCV TDISHLVRKK RKPEEESPRK DDAKKAKQEP
410 420 430 440
EVNGGSGDAV PSGNEVSENM EEEAENQAES RAAVEGTVEA GATVESTAC
Length:449
Mass (Da):48,804
Last modified:May 10, 2005 - v1
Checksum:iA69B7FE13AAA3433
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT006757 mRNA. Translation: AAP35403.1.
CH471059 Genomic DNA. Translation: EAX06964.1.
CH471059 Genomic DNA. Translation: EAX06965.1.
RefSeqiNP_689511.2. NM_152298.3.
UniGeneiHs.319334.

Genome annotation databases

GeneIDi4678.
UCSCiuc001coj.3. human.

Similar proteinsi

Entry informationi

Entry nameiQ5T626_HUMAN
AccessioniPrimary (citable) accession number: Q5T626
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: November 22, 2017
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.