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Protein
Submitted name:

Nuclear autoantigenic sperm protein (Histone-binding)

Gene

NASP

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear autoantigenic sperm protein (Histone-binding)Imported
Submitted name:
Nuclear autoantigenic sperm protein (Histone-binding), isoform CRA_aImported
Gene namesi
Name:NASPImported
ORF Names:hCG_40880Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000132780.16

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA31448

PTM / Processingi

Proteomic databases

MaxQBiQ5T626

Expressioni

Gene expression databases

BgeeiENSG00000132780
ExpressionAtlasiQ5T626 baseline and differential

Interactioni

Protein-protein interaction databases

IntActiQ5T626, 1 interactor

Structurei

3D structure databases

SMRiQ5T626
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini43 – 76TPR_REGIONInterPro annotationAdd BLAST34
Repeati43 – 76TPRPROSITE-ProRule annotationAdd BLAST34
Domaini203 – 278TPR_REGIONInterPro annotationAdd BLAST76
Repeati203 – 236TPRPROSITE-ProRule annotationAdd BLAST34
Repeati245 – 278TPRPROSITE-ProRule annotationAdd BLAST34

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili265 – 320Sequence analysisAdd BLAST56

Keywords - Domaini

Coiled coilSequence analysis, TPR repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG4563 Eukaryota
ENOG4110P5E LUCA
HOGENOMiHOG000273906
HOVERGENiHBG002186

Family and domain databases

Gene3Di1.25.40.10, 1 hit
InterProiView protein in InterPro
IPR019544 Tetratricopeptide_SHNi-TPR_dom
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat
PfamiView protein in Pfam
PF10516 SHNi-TPR, 1 hit
SMARTiView protein in SMART
SM00028 TPR, 3 hits
SUPFAMiSSF48452 SSF48452, 2 hits
PROSITEiView protein in PROSITE
PS50005 TPR, 3 hits
PS50293 TPR_REGION, 2 hits

Sequencei

Sequence statusi: Complete.

Q5T626-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAMESTATAA VAAELVSADK IEDVPAPSTS ADKVESLDVD SEAKKLLGLG
60 70 80 90 100
QKHLVMGDIP AAVNAFQEAA SLLGKKYGET ANECGEAFFF YGKSLLELAR
110 120 130 140 150
MENGVLGNAL EGVHVEEEEG EKTEDESLVE NNDNIDETEG SEEDDKENDK
160 170 180 190 200
TEEMPNDSVL ENKSLQENEE EEIGNLELAW DMLDLAKIIF KRQETKEAQL
210 220 230 240 250
YAAQAHLKLG EVSVESENYV QAVEEFQSCL NLQEQYLEAH DRLLAETHYQ
260 270 280 290 300
LGLAYGYNSQ YDEAVAQFSK SIEVIENRMA VLNEQVKEAE GSSAEYKKEI
310 320 330 340 350
EELKELLPEI REKIEDAKES QRSGNVAELA LKATLVESST SGFTPGGGGS
360 370 380 390 400
SVSMIASRKP TDGASSSNCV TDISHLVRKK RKPEEESPRK DDAKKAKQEP
410 420 430 440
EVNGGSGDAV PSGNEVSENM EEEAENQAES RAAVEGTVEA GATVESTAC
Length:449
Mass (Da):48,804
Last modified:May 10, 2005 - v1
Checksum:iA69B7FE13AAA3433
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT006757 mRNA Translation: AAP35403.1
CH471059 Genomic DNA Translation: EAX06964.1
CH471059 Genomic DNA Translation: EAX06965.1
RefSeqiNP_689511.2, NM_152298.3
UniGeneiHs.319334

Genome annotation databases

GeneIDi4678
UCSCiuc001coj.3 human

Similar proteinsi

Entry informationi

Entry nameiQ5T626_HUMAN
AccessioniPrimary (citable) accession number: Q5T626
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: May 23, 2018
This is version 123 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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