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Q5T5P2 (SKT_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Sickle tail protein homolog
Gene names
Name:KIAA1217
Synonyms:SKT
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length1943 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Required for normal development of intervertebral disks By similarity. UniProtKB A2AQ25

Subcellular location

Cytoplasm By similarity UniProtKB A2AQ25.

Sequence caution

The sequence AAH18764.1 differs from that shown. Reason: Erroneous initiation.

The sequence AL833280 differs from that shown. Reason: Frameshift at position 976.

The sequence BAC86241.1 differs from that shown. Reason: Erroneous initiation.

The sequence BAF63529.1 differs from that shown. Reason: Erroneous initiation.

The sequence CAE45879.1 differs from that shown. Reason: Erroneous termination at position 1251. Translated as Leu.

The sequence CAI12212.1 differs from that shown. Reason: Erroneous gene model prediction.

The sequence CAI14084.1 differs from that shown. Reason: Erroneous gene model prediction.

The sequence CAI40182.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
   Cellular componentCytoplasm
   Coding sequence diversityAlternative splicing
Polymorphism
   DomainCoiled coil
   Molecular functionDevelopmental protein
   PTMGlycoprotein
Phosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processembryonic skeletal system development

Inferred from sequence or structural similarity. Source: UniProtKB

   Cellular_componentcytoplasm

Inferred from sequence or structural similarity. Source: UniProtKB

Complete GO annotation...

Alternative products

This entry describes 7 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 Ref.9 (identifier: Q5T5P2-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 Ref.5 (identifier: Q5T5P2-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1139-1737: Missing.
Isoform 3 Ref.9 (identifier: Q5T5P2-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1-282: Missing.
     560-594: Missing.
     1779-1782: ANGS → VVLP
     1783-1943: Missing.
Isoform 4 Ref.4 (identifier: Q5T5P2-4)

The sequence of this isoform differs from the canonical sequence as follows:
     1-282: Missing.
     560-594: Missing.
     1139-1737: Missing.
     1779-1782: ANGS → VVLP
     1783-1943: Missing.
Isoform 5 Ref.2 (identifier: Q5T5P2-7)

The sequence of this isoform differs from the canonical sequence as follows:
     560-594: Missing.
     1179-1737: Missing.
Isoform 6 Ref.4 (identifier: Q5T5P2-6)

The sequence of this isoform differs from the canonical sequence as follows:
     1-282: Missing.
     560-594: Missing.
     1205-1737: Missing.
     1779-1782: ANGS → VVLP
     1783-1943: Missing.
Isoform 7 (identifier: Q5T5P2-8)

The sequence of this isoform differs from the canonical sequence as follows:
     1-282: Missing.
     560-594: Missing.
     1179-1737: Missing.
     1779-1782: ANGS → VVLP
     1783-1943: Missing.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 19431943Sickle tail protein homolog
PRO_0000287897

Regions

Coiled coil557 – 58125 Potential
Coiled coil644 – 68542 Potential
Coiled coil957 – 98529 Potential
Coiled coil1464 – 149027 Potential
Coiled coil1656 – 168631 Potential
Compositional bias295 – 36470Pro-rich
Compositional bias1794 – 1905112Ser-rich

Amino acid modifications

Modified residue2441Phosphotyrosine By similarity
Modified residue2451Phosphotyrosine By similarity
Modified residue3611Phosphoserine By similarity
Modified residue3931Phosphotyrosine Ref.9
Modified residue4741Phosphoserine By similarity
Modified residue10441Phosphoserine By similarity
Modified residue18961Phosphoserine By similarity UniProtKB A2AQ25
Modified residue18991Phosphoserine By similarity
Modified residue19021Phosphoserine By similarity UniProtKB A2AQ25
Glycosylation3571O-linked (GlcNAc) By similarity UniProtKB A2AQ25

Natural variations

Alternative sequence1 – 282282Missing in isoform 3, isoform 4, isoform 6 and isoform 7. Ref.2 Ref.4 Ref.9
VSP_052427
Alternative sequence560 – 59435Missing in isoform 3, isoform 4, isoform 5, isoform 6 and isoform 7. Ref.2 Ref.4 Ref.9
VSP_052428
Alternative sequence1139 – 1737599Missing in isoform 2 and isoform 4. Ref.4 Ref.5
VSP_052429
Alternative sequence1179 – 1737559Missing in isoform 5 and isoform 7.
VSP_030353
Alternative sequence1205 – 1737533Missing in isoform 6. Ref.2 Ref.4
VSP_052430
Alternative sequence1779 – 17824ANGS → VVLP in isoform 3, isoform 4, isoform 6 and isoform 7. Ref.2 Ref.4 Ref.9
VSP_052431
Alternative sequence1783 – 1943161Missing in isoform 3, isoform 4, isoform 6 and isoform 7. Ref.2 Ref.4 Ref.9
VSP_052432
Natural variant1451A → G.
Corresponds to variant rs17506606 [ dbSNP | Ensembl ].
VAR_051358
Natural variant8871A → T. Ref.4
Corresponds to variant rs10828663 [ dbSNP | Ensembl ].
VAR_051359
Natural variant13621P → A.
Corresponds to variant rs16924863 [ dbSNP | Ensembl ].
VAR_051360

Experimental info

Sequence conflict4981T → A in AL833280. Ref.1
Sequence conflict5081R → H in BX648451. Ref.1
Sequence conflict6791K → R in AL833280. Ref.1
Sequence conflict7951E → G in CAE45879. Ref.1
Sequence conflict8291T → M in BX648451. Ref.1
Sequence conflict9141A → P in BX648451. Ref.1
Sequence conflict12671S → N in BAC86241. Ref.8
Sequence conflict13061T → A in AL833280. Ref.1
Sequence conflict17431P → L in AL833280. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified May 15, 2007. Version 2.
Checksum: DFE67FADE56E0349

FASTA1,943214,116
        10         20         30         40         50         60 
MEENESQKCE PCLPYSADRR QMQEQGKGNL HVTSPEDAEC RRTKERLSNG NSRGSVSKSS 

        70         80         90        100        110        120 
RNIPRRHTLG GPRSSKEILG MQTSEMDRKR EAFLEHLKQK YPHHASAIMG HQERLRDQTR 

       130        140        150        160        170        180 
SPKLSHSPQP PSLGDPVEHL SETSADSLEA MSEGDAPTPF SRGSRTRASL PVVRSTNQTK 

       190        200        210        220        230        240 
ERSLGVLYLQ YGDETKQLRM PNEITSADTI RALFVSAFPQ QLTMKMLESP SVAIYIKDES 

       250        260        270        280        290        300 
RNVYYELNDV RNIQDRSLLK VYNKDPAHAF NHTPKTMNGD MRMQRELVYA RGDGPGAPRP 

       310        320        330        340        350        360 
GSTAHPPHAI PNSPPSTPVP HSMPPSPSRI PYGGTRSMVV PGNATIPRDR ISSLPVSRPI 

       370        380        390        400        410        420 
SPSPSAILER RDVKPDEDMS GKNIAMYRNE GFYADPYLYH EGRMSIASSH GGHPLDVPDH 

       430        440        450        460        470        480 
IIAYHRTAIR SASAYCNPSM QAEMHMEQSL YRQKSRKYPD SHLPTLGSKT PPASPHRVSD 

       490        500        510        520        530        540 
LRMIDMHAHY NAHGPPHTMQ PDRASPSRQA FKKEPGTLVY IEKPRSAAGL SSLVDLGPPL 

       550        560        570        580        590        600 
MEKQVFAYST ATIPKDRETR ERMQAMEKQI ASLTGLVQSA LFKGPITSYS KDASSEKMMK 

       610        620        630        640        650        660 
TTANRNHTDS AGTPHVSGGK MLSALESTVP PSQPPPVGTS AIHMSLLEMR RSVAELRLQL 

       670        680        690        700        710        720 
QQMRQLQLQN QELLRAMMKK AELEISGKVM ETMKRLEDPV QRQRVLVEQE RQKYLHEEEK 

       730        740        750        760        770        780 
IVKKLCELED FVEDLKKDST AASRLVTLKD VEDGAFLLRQ VGEAVATLKG EFPTLQNKMR 

       790        800        810        820        830        840 
AILRIEVEAV RFLKEEPHKL DSLLKRVRSM TDVLTMLRRH VTDGLLKGTD AAQAAQYMAM 

       850        860        870        880        890        900 
EKATAAEVLK SQEEAAHTSG QPFHSTGAPG DAKSEVVPLS GMMVRHAQSS PVVIQPSQHS 

       910        920        930        940        950        960 
VALLNPAQNL PHVASSPAVP QEATSTLQMS QAPQSPQIPM NGSAMQSLFI EEIHSVSAKN 

       970        980        990       1000       1010       1020 
RAVSIEKAEK KWEEKRQNLD HYNGKEFEKL LEEAQANIMK SIPNLEMPPA TGPLPRGDAP 

      1030       1040       1050       1060       1070       1080 
VDKVELSEDS PNSEQDLEKL GGKSPPPPPP PPRRSYLPGS GLTTTRSGDV VYTGRKENIT 

      1090       1100       1110       1120       1130       1140 
AKASSEDAGP SPQTRATKYP AEEPASAWTP SPPPVTTSSS KDEEEEEEEG DKIMAELQAF 

      1150       1160       1170       1180       1190       1200 
QKCSFMDVNS NSHAEPSRAD SHVKDTRSGA TVPPKEKKNL EFFHEDVRKS DVEYENGPQM 

      1210       1220       1230       1240       1250       1260 
EFQKVTTGAV RPSDPPKWER GMENSISDAS RTSEYKTEII MKENSISNMS LLRDSRNYSQ 

      1270       1280       1290       1300       1310       1320 
ETVPKASFGF SGISPLEDEI NKGSKISGLQ YSIPDTENQT LNYGKTKEME KQNTDKCHVS 

      1330       1340       1350       1360       1370       1380 
SHTRLTESSV HDFKTEDQEV ITTDFGQVVL RPKEARHANV NPNEDGESSS SSPTEENAAT 

      1390       1400       1410       1420       1430       1440 
DNIAFMITET TVQVLSSGEV HDIVSQKGED IQTVNIDARK EMTPRQEGTD NEDPVVCLDK 

      1450       1460       1470       1480       1490       1500 
KPVIIIFDEP MDIRSAYKRL STIFEECDEE LERMMMEEKI EEEEEEENGD SVVQNNNTSQ 

      1510       1520       1530       1540       1550       1560 
MSHKKVAPGN LRTGQQVETK SQPHSLATET RNPGGQEMNR TELNKFSHVD SPNSECKGED 

      1570       1580       1590       1600       1610       1620 
ATDDQFESPK KKFKFKFPKK QLAALTQAIR TGTKTGKKTL QVVVYEEEEE DGTLKQHKEA 

      1630       1640       1650       1660       1670       1680 
KRFEIARSQP EDTPENTVRR QEQPSIESTS PISRTDEIRK NTYRTLDSLE QTIKQLENTI 

      1690       1700       1710       1720       1730       1740 
SEMSPKALVD TSCSSNRDSV ASSSHIAQEA SPRPLLVPDE GPTALEPPTS IPSASRKGSS 

      1750       1760       1770       1780       1790       1800 
GAPQTSRMPV PMSAKNRPGT LDKPGKQSKL QDPRQYRQAN GSAKKSGGDF KPTSPSLPAS 

      1810       1820       1830       1840       1850       1860 
KIPALSPSSG KSSSLPSSSG DSSNLPNPPA TKPSIASNPL SPQTGPPAHS ASLIPSVSNG 

      1870       1880       1890       1900       1910       1920 
SLKFQSLTHT GKGHHLSFSP QSQNGRAPPP LSFSSSPPSP ASSVSLNQGA KGTRTIHTPS 

      1930       1940 
LTSYKAQNGS SSKATPSTAK ETS

« Hide

Isoform 2 [UniParc].

Checksum: 5648CE8248B1ADA7
Show »

FASTA1,344146,879
Isoform 3 [UniParc].

Checksum: 418F12AC78926686
Show »

FASTA1,465162,360
Isoform 4 [UniParc].

Checksum: 24CDAF47EE1EBB7E
Show »

FASTA86695,123
Isoform 5 [UniParc].

Checksum: F2BA6806FFB23CB1
Show »

FASTA1,349147,424
Isoform 6 [UniParc].

Checksum: FA65349E05AFBC5B
Show »

FASTA932102,692
Isoform 7 [UniParc].

Checksum: 14A5BFA2BE6A6007
Show »

FASTA90699,494

References

« Hide 'large scale' references
[1]"The full-ORF clone resource of the German cDNA consortium."
Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I.
BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 3 AND 7), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 925-1943 (ISOFORM 2).
Tissue: Amygdala, Carcinoma, Endometrial adenocarcinoma and Skeletal muscle.
[2]"The DNA sequence and comparative analysis of human chromosome 10."
Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J. expand/collapse author list , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.
Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. expand/collapse author list , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 4 AND 6), VARIANT THR-887.
Tissue: Chondrosarcoma and Uterus.
[5]"Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
Nagase T., Ishikawa K., Kikuno R., Hirosawa M., Nomura N., Ohara O.
DNA Res. 6:337-345(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 24-1943 (ISOFORM 2).
Tissue: Brain.
[6]"Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."
Nakajima D., Okazaki N., Yamakawa H., Kikuno R., Ohara O., Nagase T.
DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: SEQUENCE REVISION.
[7]"A human Sickle tail (SKT) expresses especially in notochordal cells."
Semba K., Araki K., Araki M., Abe K., Yamamura K.
Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 25-1943 (ISOFORM 5).
[8]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1248-1943 (ISOFORM 3).
Tissue: Mammary gland.
[9]"Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules."
Zhang Y., Wolf-Yadlin A., Ross P.L., Pappin D.J., Rush J., Lauffenburger D.A., White F.M.
Mol. Cell. Proteomics 4:1240-1250(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-393, MASS SPECTROMETRY.
Tissue: Mammary epithelium.
[10]"A quantitative atlas of mitotic phosphorylation."
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Cervix carcinoma.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL157473 mRNA. Translation: CAB75668.1.
AL833280 mRNA. No translation available.
BX640796 mRNA. Translation: CAE45879.1. Sequence problems.
BX648451 mRNA. No translation available.
AL353583, AL392104 Genomic DNA. Translation: CAI12211.2.
AL353583 expand/collapse EMBL AC list , AC063961, AL356113, AL392104 Genomic DNA. Translation: CAI12212.1. Sequence problems.
AL353583 expand/collapse EMBL AC list , AC063961, AL356113, AL392104 Genomic DNA. Translation: CAI12213.2.
AL353583, AL392104 Genomic DNA. Translation: CAO03598.1.
AL353583, AL392104 Genomic DNA. Translation: CAO03599.1.
AL353583, AL392104 Genomic DNA. Translation: CAO03600.1.
AL356113 expand/collapse EMBL AC list , AC063961, AL353583, AL392104 Genomic DNA. Translation: CAI14084.1. Sequence problems.
AL356113 expand/collapse EMBL AC list , AC063961, AL353583, AL392104 Genomic DNA. Translation: CAI14085.2.
AL392104, AL353583 Genomic DNA. Translation: CAI40179.2.
AL392104 expand/collapse EMBL AC list , AC063961, AL353583, AL356113 Genomic DNA. Translation: CAI40182.1. Sequence problems.
AL392104 expand/collapse EMBL AC list , AC063961, AL353583, AL356113 Genomic DNA. Translation: CAI40183.2.
AL392104, AL353583 Genomic DNA. Translation: CAO03477.1.
AL392104, AL353583 Genomic DNA. Translation: CAO03478.1.
AL392104, AL353583 Genomic DNA. Translation: CAO03479.1.
CH471072 Genomic DNA. Translation: EAW86124.1.
BC018764 mRNA. Translation: AAH18764.1. Different initiation.
BC098577 mRNA. Translation: AAH98577.1.
AB033043 mRNA. Translation: BAA86531.2. Sequence problems.
AB291616 mRNA. Translation: BAF63529.1. Different initiation.
AK125675 mRNA. Translation: BAC86241.1. Different initiation.
IPIIPI00103018.
IPI00645403.
IPI00845521.
IPI00853173.
IPI00855886.
IPI00878042.
IPI01010021.
PIRT46910.
RefSeqNP_001091970.1. NM_001098500.1.
NP_001091971.1. NM_001098501.1.
NP_062536.2. NM_019590.3.
UniGeneHs.445885.

3D structure databases

ProteinModelPortalQ5T5P2.
ModBaseSearch...

Protein-protein interaction databases

IntActQ5T5P2. 7 interactions.
MINTMINT-1464937.

PTM databases

PhosphoSiteQ5T5P2.

Polymorphism databases

DMDM147733121.

Proteomic databases

PaxDbQ5T5P2.
PRIDEQ5T5P2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000307544; ENSP00000302343; ENSG00000120549.
ENST00000376451; ENSP00000365634; ENSG00000120549.
ENST00000376454; ENSP00000365637; ENSG00000120549.
ENST00000376462; ENSP00000365645; ENSG00000120549.
ENST00000396445; ENSP00000379722; ENSG00000120549.
ENST00000396446; ENSP00000379723; ENSG00000120549.
ENST00000458595; ENSP00000392625; ENSG00000120549.
GeneID56243.
KEGGhsa:56243.
UCSCuc001irs.3. human.
uc001irt.4. human.
uc001iru.4. human.
uc001irw.3. human.
uc001irx.3. human.
uc001iry.3. human.
uc001irz.3. human.

Organism-specific databases

CTD56243.
GeneCardsGC10P024023.
H-InvDBHIX0008709.
HGNCHGNC:25428. KIAA1217.
HPAHPA004941.
neXtProtNX_Q5T5P2.
PharmGKBPA134893343.
HUGESearch...
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG72706.
HOVERGENHBG019587.
InParanoidQ5T5P2.
OMAENGPQME.

Gene expression databases

ArrayExpressQ5T5P2.
BgeeQ5T5P2.
CleanExHS_KIAA1217.
GenevestigatorQ5T5P2.

Family and domain databases

InterProIPR026725. Skt.
[Graphical view]
PANTHERPTHR22741:SF4. PTHR22741:SF4. 1 hit.
ProtoNetSearch...

Other

ChiTaRSKIAA1217. human.
GenomeRNAi56243.
NextBio61856.

Entry information

Entry nameSKT_HUMAN
AccessionPrimary (citable) accession number: Q5T5P2
Secondary accession number(s): A5LHW9 expand/collapse secondary AC list , A6PVQ5, A6PVQ6, A6PVQ7, Q4KMG4, Q5T5P3, Q5T7H3, Q6MZZ6, Q6ZUI4, Q8WV45, Q9NSR2, Q9ULK3
Entry history
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: May 15, 2007
Last modified: April 3, 2013
This is version 76 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Human chromosome 10

Human chromosome 10: entries, gene names and cross-references to MIM

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

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