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Protein
Submitted name:

Serine--tRNA ligase, cytoplasmic

Gene

SARS

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Serine--tRNA ligase, cytoplasmicImported
Gene namesi
Name:SARSImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000031698.12.
HGNCiHGNC:10537. SARS.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000031698.

PTM / Processingi

Proteomic databases

EPDiQ5T5C7.
MaxQBiQ5T5C7.
PaxDbiQ5T5C7.
PeptideAtlasiQ5T5C7.
PRIDEiQ5T5C7.

Expressioni

Gene expression databases

BgeeiENSG00000031698.
ExpressionAtlasiQ5T5C7. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliQ5T5C7.
SMRiQ5T5C7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini203 – 475AA_TRNA_LIGASE_IIInterPro annotationAdd BLAST273

Phylogenomic databases

eggNOGiKOG2509. Eukaryota.
COG0172. LUCA.
GeneTreeiENSGT00790000123098.
HOGENOMiHOG000035937.
HOVERGENiHBG023172.
OMAiSPCFRRE.
OrthoDBiEOG091G05KR.
PhylomeDBiQ5T5C7.

Family and domain databases

CDDicd00770. SerRS_core. 1 hit.
InterProiView protein in InterPro
IPR002314. aa-tRNA-synt_IIb.
IPR006195. aa-tRNA-synth_II.
IPR002317. Ser-tRNA-ligase_type_1.
IPR015866. Ser-tRNA-synth_1_N.
IPR033729. SerRS_core.
IPR010978. tRNA-bd_arm.
PANTHERiPTHR11778. PTHR11778. 1 hit.
PfamiView protein in Pfam
PF02403. Seryl_tRNA_N. 1 hit.
PF00587. tRNA-synt_2b. 1 hit.
PRINTSiPR00981. TRNASYNTHSER.
SUPFAMiSSF46589. SSF46589. 2 hits.
TIGRFAMsiTIGR00414. serS. 1 hit.
PROSITEiView protein in PROSITE
PS50862. AA_TRNA_LIGASE_II. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5T5C7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVLDLDLFRV DKGGDPALIR ETQEKRFKDP GLVDQLVKAD SEWRRCRFRA
60 70 80 90 100
DNLNKLKNLC SKTIGEKMKK KEPVGDDESV PENVLSFDDL TADALANLKV
110 120 130 140 150
SQIKKVRLLI DEAILKCDAE RIKLEAERFE NLREIGNLLH PSVPISNDED
160 170 180 190 200
VDNKVERIWG DCTVRKKYSH VDLVVMVDGF EGEKGAVVAG SRGYFLKGVL
210 220 230 240 250
VFLEQALIQY ALRTLGSRGY IPIYTPFFMR KEVMQEVAQL SQFDEELYKV
260 270 280 290 300
IGKGSEKSDD NSYDEKYLIA TSEQPIAALH RDEWLRPEDL PIKYAGLSTC
310 320 330 340 350
FRQEVGSHGR DTRGIFRVHQ FEKIEQFVYS SPHDNKSWEM FEEMITTAEE
360 370 380 390 400
FYQSLGIPYH IVNIVSGSLN HAASKKLDLE AWFPGSGAFR ELVSCSNCTD
410 420 430 440 450
YQARRLRIRY GQTKKMMDKR KNNLHLSTQN KLEASLFSPK KVEFVHMLNA
460 470 480 490 500
TMCATTRTIC AILENYQTEK GITVPEKLKE FMPPGLQELI PFVKPAPIEQ
510 520 530
EPSKKQKKQH EGSKKKAAAR DVTLENRLQN MEVTDA
Length:536
Mass (Da):61,313
Last modified:December 21, 2004 - v1
Checksum:i8ADA07F1F6E88A04
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL356389 Genomic DNA. No translation available.
RefSeqiNP_001317598.1. NM_001330669.1.
UniGeneiHs.531176.

Genome annotation databases

EnsembliENST00000369923; ENSP00000358939; ENSG00000031698.
GeneIDi6301.
UCSCiuc057ixz.1. human.

Similar proteinsi

Entry informationi

Entry nameiQ5T5C7_HUMAN
AccessioniPrimary (citable) accession number: Q5T5C7
Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: September 27, 2017
This is version 123 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported