Unreviewed, UniProtKB/TrEMBL Q5T411 (Q5T411_HUMAN)

Names and origin

Protein names

Submitted name:
    MutY homolog (E. coli) EMBL CAI21717.1

Gene names

Name:	MUTYH EMBL CAI21717.1
ORF Names:	RP4-534D1.2-006 EMBL CAI21717.1

Organism

Homo sapiens (Human) EMBL CAI21717.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	546 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Gene Ontology (GO)
Biological process	base-excision repair Inferred from electronic annotation. Source: InterPro
Cellular component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular function	4 iron, 4 sulfur cluster binding Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro endonuclease activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL CAI21717.1

Sequences

	Sequence		Length	Mass (Da)
	Q5T411-1 [UniParc]. Last modified December 21, 2004. Version 1. Checksum: A7EE5E759E9CAE65	FASTA	546	60,013
	10 20 30 40 50 60 SVFCCLHQRG PRAIMRKPRA AVGSGHRKQA ASQEGRQKHA KNNSQAKPSA CDGMIAECPG 70 80 90 100 110 120 APAGLARQPE EVVLQASVSS YHLFRDVAEV TAFRGSLLSW YDQEKRDLPW RRRAEDEMDL 130 140 150 160 170 180 DRRAYAVWVS EVMLQQTQVA TVINYYTGWM QKWPTLQDLA SASLEEVNQL WAGLGYYSRG 190 200 210 220 230 240 RRLQEGARKV VEELGGHMPR TAETLQQLLP GVGRYTAGAI ASIAFGQATG VVDGNVARVL 250 260 270 280 290 300 CRVRAIGADP SSTLVSQQLW GLAQQLVDPA RPGDFNQAAM ELGATVCTPQ RPLCSQCPVE 310 320 330 340 350 360 SLCRARQRVE QEQLLASGSL SGSPDVEECA PNTGQCHLCL PPSEPWDQTL GVVNFPRKAS 370 380 390 400 410 420 RKPPREESSA TCVLEQPGAL GAQILLVQRP NSGLLAGLWE FPSVTWEPSE QLQRKALLQE 430 440 450 460 470 480 LQRWAGPLPA THLRHLGEVV HTFSHIKLTY QVYGLALEGQ TPVTTVPPGA RWLTQEEFHT 490 500 510 520 530 540 AAVSTAMKKV FRVYQGQQPG TCMGSKRSQV SSPCSRKKPR MGQQVLDNFF RSHISTDAHS LNSAAQ

References

[1]	Johnson C. Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL359540 Genomic DNA. Translation: CAI21717.1.
UniGene	Hs.271353
3D structure databases
SMR	Q5T411. Positions 356-497.
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000132781. Homo sapiens. [Contig view]
Organism-specific databases
HGNC	HGNC:7527. MUTYH.
GenAtlas	Search...
GeneCards	Search...
Phylogenomic databases
HOGENOM	Q5T411.
HOVERGEN	Q5T411.
Gene expression databases
ArrayExpress	Q5T411.
Family and domain databases
InterPro	IPR004036. Endonuclease-III_CS2. IPR004035. Endouclease-III_FeS-bd_CS1. IPR003651. FeS_bd. IPR000445. HhH. IPR003265. HhH-GPD_domain. IPR000086. NUDIX_hydrolase_core. [Graphical view]
Gene3D	G3DSA:3.90.79.10. NUDIX_hydrolase. 1 hit.
Pfam	PF00633. HHH. 1 hit. PF00730. HhH-GPD. 1 hit. PF00293. NUDIX. 1 hit. [Graphical view]
SMART	SM00478. ENDO3c. 1 hit. SM00525. FES. 1 hit. [Graphical view]
PROSITE	PS00764. ENDONUCLEASE_III_1. 1 hit. PS01155. ENDONUCLEASE_III_2. 1 hit. [Graphical view]

Entry information

Entry name

Q5T411_HUMAN

Accession

Primary (citable) accession number: Q5T411

Entry history

Integrated into UniProtKB/TrEMBL:	December 21, 2004
Last sequence update:	December 21, 2004
Last modified:	November 25, 2008
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)