Q5T3U5 (MRP7_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Multidrug resistance-associated protein 7

Alternative name(s):
ATP-binding cassette sub-family C member 10

Gene names

Name:	ABCC10
Synonyms:	MRP7, SIMRP7

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	1492 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion. Ref.5 Ref.6
Subcellular location	Cell membrane; Multi-pass membrane protein Ref.1 Ref.6.
Tissue specificity	Isoform 1 is specifically expressed in spleen. Isoform 2 is more widely expressed. Ref.1
Sequence similarities	Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. [View classification] Contains 2 ABC transmembrane type-1 domains. Contains 2 ABC transporter domains.
Biophysicochemical properties	Kinetic parameters: KM=57.8 µM for 17-beta-estradiol 17-(beta-D-glucuronide) (at 37 degrees Celsius) Ref.5 Vmax=20 pmol/min/mg enzyme toward 17-beta-estradiol 17-(beta-D-glucuronide) (at 37 degrees Celsius)
Sequence caution	The sequence BAA92227.1 differs from that shown. Reason: Erroneous initiation. The sequence BAB15736.1 differs from that shown. Reason: Intron retention.

Ontologies

Keywords
Biological process	Transport
Cellular component	Cell membrane Membrane
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Repeat Transmembrane Transmembrane helix
Ligand	ATP-binding Nucleotide-binding
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity, coupled to transmembrane movement of substances Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q5T3U5-1)

Also known as: Mrp7;

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q5T3U5-2)

Also known as: Mrp7A;

The sequence of this isoform differs from the canonical sequence as follows:
     1-43: Missing.
     44-52: VLSACYLGT → MCLLVFPLV
     588-588: P → PDCGRLGAQIKWLLCS

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1492	1492	Multidrug resistance-associated protein 7		PRO_0000253576
Regions
	Transmembrane	32 – 52	21	Helical; Potential
	Transmembrane	70 – 90	21	Helical; Potential
	Transmembrane	102 – 122	21	Helical; Potential
	Transmembrane	133 – 153	21	Helical; Potential
	Transmembrane	172 – 192	21	Helical; Potential
	Transmembrane	293 – 313	21	Helical; Potential
	Transmembrane	320 – 340	21	Helical; Potential
	Transmembrane	391 – 411	21	Helical; Potential
	Transmembrane	414 – 434	21	Helical; Potential
	Transmembrane	507 – 527	21	Helical; Potential
	Transmembrane	538 – 558	21	Helical; Potential
	Transmembrane	875 – 895	21	Helical; Potential
	Transmembrane	933 – 953	21	Helical; Potential
	Transmembrane	974 – 994	21	Helical; Potential
	Transmembrane	1051 – 1071	21	Helical; Potential
	Transmembrane	1153 – 1173	21	Helical; Potential
	Transmembrane	1182 – 1202	21	Helical; Potential
	Domain	285 – 563	279	ABC transmembrane type-1 1
	Domain	598 – 824	227	ABC transporter 1
	Domain	885 – 1210	326	ABC transmembrane type-1 2
	Domain	1246 – 1479	234	ABC transporter 2
	Nucleotide binding	633 – 640	8	ATP 1 Potential
	Nucleotide binding	1280 – 1287	8	ATP 2 Potential
Amino acid modifications
	Modified residue	463	1	Phosphothreonine Ref.7
	Modified residue	467	1	Phosphoserine Ref.7
Natural variations
	Alternative sequence	1 – 43	43	Missing in isoform 2.		VSP_021078
	Alternative sequence	44 – 52	9	VLSACYLGT → MCLLVFPLV in isoform 2.		VSP_021079
	Alternative sequence	588	1	P → PDCGRLGAQIKWLLCS in isoform 2.		VSP_021080
	Natural variant	948	1	I → T. Corresponds to variant rs2125739 [ dbSNP | Ensembl ].		VAR_028391
Experimental info
	Sequence conflict	208	1	D → E in AAK39642. Ref.1
	Sequence conflict	220	1	Missing in AAK39642. Ref.1
	Sequence conflict	631	1	I → T in AAK39642. Ref.1
	Sequence conflict	764	1	L → P in AAK39642. Ref.1
	Sequence conflict	809	1	S → P in AAK39642. Ref.1
	Sequence conflict	888	1	I → T in AAK39642. Ref.1
	Sequence conflict	1030	1	S → F in AAK39642. Ref.1
	Sequence conflict	1134	1	L → F in BAB15736. Ref.2
	Sequence conflict	1276	1	L → V in AAK39642. Ref.1
	Sequence conflict	1455	1	G → E in AAK39642. Ref.1
	Sequence conflict	1481	1	S → C in AAK39642. Ref.1
	Sequence conflict	1490	1	G → R in AAK39642. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 (Mrp7) [UniParc]. Last modified December 21, 2004. Version 1. Checksum: 6FBC260DEFB3DF30	FASTA	1,492	161,629
	10 20 30 40 50 60 MERLLAQLCG SSAAWPLPLW EGDTTGHCFT QLVLSALPHA LLAVLSACYL GTPRSPDYIL 70 80 90 100 110 120 PCSPGWRLRL AASFLLSVFP LLDLLPVALP PGAGPGPIGL EVLAGCVAAV AWISHSLALW 130 140 150 160 170 180 VLAHSPHGHS RGPLALALVA LLPAPALVLT VLWHCQRGTL LPPLLPGPMA RLCLLILQLA 190 200 210 220 230 240 ALLAYALGWA APGGPREPWA QEPLLPEDQE PEVAEDGESW LSRFSYAWLA PLLARGACGE 250 260 270 280 290 300 LRQPQDICRL PHRLQPTYLA RVFQAHWQEG ARLWRALYGA FGRCYLALGL LKLVGTMLGF 310 320 330 340 350 360 SGPLLLSLLV GFLEEGQEPL SHGLLYALGL AGGAVLGAVL QNQYGYEVYK VTLQARGAVL 370 380 390 400 410 420 NILYCKALQL GPSRPPTGEA LNLLGTDSER LLNFAGSFHE AWGLPLQLAI TLYLLYQQVG 430 440 450 460 470 480 VAFVGGLILA LLLVPVNKVI ATRIMASNQE MLQHKDARVK LVTELLSGIR VIKFCGWEQA 490 500 510 520 530 540 LGARVEACRA RELGRLRVIK YLDAACVYLW AALPVVISIV IFITYVLMGH QLTATKVFTA 550 560 570 580 590 600 LALVRMLILP LNNFPWVING LLEAKVSLDR IQLFLDLPNH NPQAYYSPDP PAEPSTVLEL 610 620 630 640 650 660 HGALFSWDPV GTSLETFISH LEVKKGMLVG IVGKVGCGKS SLLAAIAGEL HRLRGHVAVR 670 680 690 700 710 720 GLSKGFGLAT QEPWIQFATI RDNILFGKTF DAQLYKEVLE ACALNDDLSI LPAGDQTEVG 730 740 750 760 770 780 EKGVTLSGGQ RARIALARAV YQEKELYLLD DPLAAVDADV ANHLLHRCIL GMLSYTTRLL 790 800 810 820 830 840 CTHRTEYLER ADAVLLMEAG RLIRAGPPSE ILPLVQAVPK AWAENGQESD SATAQSVQNP 850 860 870 880 890 900 EKTKEGLEEE QSTSGRLLQE ESKKEGAVAL HVYQAYWKAV GQGLALAILF SLLLMQATRN 910 920 930 940 950 960 AADWWLSHWI SQLKAENSSQ EAQPSTSPAS MGLFSPQLLL FSPGNLYIPV FPLPKAAPNG 970 980 990 1000 1010 1020 SSDIRFYLTV YATIAGVNSL CTLLRAVLFA AGTLQAAATL HRRLLHRVLM APVTFFNATP 1030 1040 1050 1060 1070 1080 TGRILNRFSS DVACADDSLP FILNILLANA AGLLGLLAVL GSGLPWLLLL LPPLSIMYYH 1090 1100 1110 1120 1130 1140 VQRHYRASSR ELRRLGSLTL SPLYSHLADT LAGLSVLRAT GATYRFEEEN LRLLELNQRC 1150 1160 1170 1180 1190 1200 QFATSATMQW LDIRLQLMGA AVVSAIAGIA LVQHQQGLAN PGLVGLSLSY ALSLTGLLSG 1210 1220 1230 1240 1250 1260 LVSSFTQTEA MLVSVERLEE YTCDLPQEPQ GQPLQLGTGW LTQGGVEFQD VVLAYRPGLP 1270 1280 1290 1300 1310 1320 NALDGVTFCV QPGEKLGIVG RTGSGKSSLL LVLFRLLEPS SGRVLLDGVD TSQLELAQLR 1330 1340 1350 1360 1370 1380 SQLAIIPQEP FLFSGTVREN LDPQGLHKDR ALWQALKQCH LSEVITSMGG LDGELGEGGR 1390 1400 1410 1420 1430 1440 SLSLGQRQLL CLARALLTDA KILCIDEATA SVDQKTDQLL QQTICKRFAN KTVLTIAHRL 1450 1460 1470 1480 1490 NTILNSDRVL VLQAGRVVEL DSPATLRNQP HSLFQQLLQS SQQGVPASLG GP
	Isoform 2 (Mrp7A) [UniParc]. Checksum: 31644BE052337EB3	FASTA	1,464	158,781
	10 20 30 40 50 60 MCLLVFPLVP RSPDYILPCS PGWRLRLAAS FLLSVFPLLD LLPVALPPGA GPGPIGLEVL 70 80 90 100 110 120 AGCVAAVAWI SHSLALWVLA HSPHGHSRGP LALALVALLP APALVLTVLW HCQRGTLLPP 130 140 150 160 170 180 LLPGPMARLC LLILQLAALL AYALGWAAPG GPREPWAQEP LLPEDQEPEV AEDGESWLSR 190 200 210 220 230 240 FSYAWLAPLL ARGACGELRQ PQDICRLPHR LQPTYLARVF QAHWQEGARL WRALYGAFGR 250 260 270 280 290 300 CYLALGLLKL VGTMLGFSGP LLLSLLVGFL EEGQEPLSHG LLYALGLAGG AVLGAVLQNQ 310 320 330 340 350 360 YGYEVYKVTL QARGAVLNIL YCKALQLGPS RPPTGEALNL LGTDSERLLN FAGSFHEAWG 370 380 390 400 410 420 LPLQLAITLY LLYQQVGVAF VGGLILALLL VPVNKVIATR IMASNQEMLQ HKDARVKLVT 430 440 450 460 470 480 ELLSGIRVIK FCGWEQALGA RVEACRAREL GRLRVIKYLD AACVYLWAAL PVVISIVIFI 490 500 510 520 530 540 TYVLMGHQLT ATKVFTALAL VRMLILPLNN FPWVINGLLE AKVSLDRIQL FLDLPNHNPQ 550 560 570 580 590 600 AYYSPDCGRL GAQIKWLLCS DPPAEPSTVL ELHGALFSWD PVGTSLETFI SHLEVKKGML 610 620 630 640 650 660 VGIVGKVGCG KSSLLAAIAG ELHRLRGHVA VRGLSKGFGL ATQEPWIQFA TIRDNILFGK 670 680 690 700 710 720 TFDAQLYKEV LEACALNDDL SILPAGDQTE VGEKGVTLSG GQRARIALAR AVYQEKELYL 730 740 750 760 770 780 LDDPLAAVDA DVANHLLHRC ILGMLSYTTR LLCTHRTEYL ERADAVLLME AGRLIRAGPP 790 800 810 820 830 840 SEILPLVQAV PKAWAENGQE SDSATAQSVQ NPEKTKEGLE EEQSTSGRLL QEESKKEGAV 850 860 870 880 890 900 ALHVYQAYWK AVGQGLALAI LFSLLLMQAT RNAADWWLSH WISQLKAENS SQEAQPSTSP 910 920 930 940 950 960 ASMGLFSPQL LLFSPGNLYI PVFPLPKAAP NGSSDIRFYL TVYATIAGVN SLCTLLRAVL 970 980 990 1000 1010 1020 FAAGTLQAAA TLHRRLLHRV LMAPVTFFNA TPTGRILNRF SSDVACADDS LPFILNILLA 1030 1040 1050 1060 1070 1080 NAAGLLGLLA VLGSGLPWLL LLLPPLSIMY YHVQRHYRAS SRELRRLGSL TLSPLYSHLA 1090 1100 1110 1120 1130 1140 DTLAGLSVLR ATGATYRFEE ENLRLLELNQ RCQFATSATM QWLDIRLQLM GAAVVSAIAG 1150 1160 1170 1180 1190 1200 IALVQHQQGL ANPGLVGLSL SYALSLTGLL SGLVSSFTQT EAMLVSVERL EEYTCDLPQE 1210 1220 1230 1240 1250 1260 PQGQPLQLGT GWLTQGGVEF QDVVLAYRPG LPNALDGVTF CVQPGEKLGI VGRTGSGKSS 1270 1280 1290 1300 1310 1320 LLLVLFRLLE PSSGRVLLDG VDTSQLELAQ LRSQLAIIPQ EPFLFSGTVR ENLDPQGLHK 1330 1340 1350 1360 1370 1380 DRALWQALKQ CHLSEVITSM GGLDGELGEG GRSLSLGQRQ LLCLARALLT DAKILCIDEA 1390 1400 1410 1420 1430 1440 TASVDQKTDQ LLQQTICKRF ANKTVLTIAH RLNTILNSDR VLVLQAGRVV ELDSPATLRN 1450 1460 QPHSLFQQLL QSSQQGVPAS LGGP

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genomic structure, gene expression, and promoter analysis of human multidrug resistance-associated protein 7." Kao H.-H., Chang M.-S., Cheng J.-F., Huang J.-D. J. Biomed. Sci. 10:98-110(2003) [PubMed: 12566991] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), TISSUE SPECIFICITY, SUBCELLULAR LOCATION. Tissue: Small intestine.
[2]	"Characterization of long cDNA clones from human adult spleen." Hattori A., Okumura K., Nagase T., Kikuno R., Hirosawa M., Ohara O. DNA Res. 7:357-366(2000) [PubMed: 11214971] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). Tissue: Spleen.
[3]	"The DNA sequence and analysis of human chromosome 6." Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D. , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P., Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V., Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J., Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E., Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A., Frankland J., French L., Garner P., Garnett J., Ghori M.J., Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M., Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S., Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R., Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E., Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A., Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K., McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T., Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R., Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W., Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M., Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L., Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J., Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L., Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W., Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S. Nature 425:805-811(2003) [PubMed: 14574404] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]	"The full-ORF clone resource of the German cDNA consortium." Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I. BMC Genomics 8:399-399(2007) [PubMed: 17974005] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 793-1492 (ISOFORMS 1/2). Tissue: Testis.
[5]	"Characterization of the transport properties of human multidrug resistance protein 7 (MRP7, ABCC10)." Chen Z.-S., Hopper-Borge E., Belinsky M.G., Shchaveleva I., Kotova E., Kruh G.D. Mol. Pharmacol. 63:351-358(2003) [PubMed: 12527806] [Abstract] Cited for: FUNCTION, BIOPHYSICOCHEMICAL PROPERTIES.
[6]	"Analysis of the drug resistance profile of multidrug resistance protein 7 (ABCC10): resistance to docetaxel." Hopper-Borge E., Chen Z.-S., Shchaveleva I., Belinsky M.G., Kruh G.D. Cancer Res. 64:4927-4930(2004) [PubMed: 15256465] [Abstract] Cited for: FUNCTION, SUBCELLULAR LOCATION.
[7]	"Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis." Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D., Yates J.R. III J. Proteome Res. 7:1346-1351(2008) [PubMed: 18220336] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-463 AND SER-467, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY032599 mRNA. Translation: AAK39642.1. AK000002 mRNA. Translation: BAA92227.1. Different initiation. AK024446 mRNA. Translation: BAB15736.1. Sequence problems. AL359813 Genomic DNA. Translation: CAI23217.1. AL133613 mRNA. Translation: CAB63742.1.
IPI	IPI00168635. IPI00396528.
PIR	T43469.
RefSeq	NP_001185863.1. NM_001198934.1. NP_258261.2. NM_033450.2.
UniGene	Hs.55879.
3D structure databases
HSSP	HSSP built from PDB template 2CBZ based on UniProtKB P33527.
ProteinModelPortal	Q5T3U5.
SMR	Q5T3U5. Positions 565-824, 873-1482.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5T3U5.
PTM databases
PhosphoSite	Q5T3U5.
Polymorphism databases
DMDM	74756298.
Proteomic databases
PRIDE	Q5T3U5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000372530; ENSP00000361608; ENSG00000124574.
GeneID	89845.
KEGG	hsa:89845.
UCSC	uc003ouy.1. human. uc003ouz.1. human. uc010jyo.1. human.
Organism-specific databases
CTD	89845.
GeneCards	GC06P043442.
H-InvDB	HIX0005903.
HGNC	HGNC:52. ABCC10.
MIM	612509. gene.
neXtProt	NX_Q5T3U5.
PharmGKB	PA24392.
GenAtlas	Search...
Phylogenomic databases
HOGENOM	HBG758042.
HOVERGEN	HBG107141.
InParanoid	Q5T3U5.
OMA	CRLPHRL.
OrthoDB	EOG4M397Q.
PhylomeDB	Q5T3U5.
Enzyme and pathway databases
Reactome	REACT_15518. Transmembrane transport of small molecules.
Gene expression databases
ArrayExpress	Q5T3U5.
Bgee	Q5T3U5.
CleanEx	HS_ABCC10.
Genevestigator	Q5T3U5.
GermOnline	ENSG00000124574. Homo sapiens.
Family and domain databases
InterPro	IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR017940. ABC_transporter_type1. IPR001140. ABC_transptr_TM_dom. IPR011527. ABC_transptrTM_dom_typ1. IPR003593. ATPase_AAA+_core. [Graphical view]
KO	K05674.
Pfam	PF00664. ABC_membrane. 2 hits. PF00005. ABC_tran. 2 hits. [Graphical view]
SMART	SM00382. AAA. 2 hits. [Graphical view]
SUPFAM	SSF90123. ABC_TM_1. 2 hits.
PROSITE	PS50929. ABC_TM1F. 2 hits. PS00211. ABC_TRANSPORTER_1. 2 hits. PS50893. ABC_TRANSPORTER_2. 2 hits. [Graphical view]
ProtoNet	Search...
Other
NextBio	76328.
SOURCE	Search...

Entry information

Entry name

MRP7_HUMAN

Accession

Primary (citable) accession number: Q5T3U5
Secondary accession number(s): Q8NHX7 , Q9H7N2, Q9NXY3, Q9UF48

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 17, 2006
Last sequence update:	December 21, 2004
Last modified:	January 25, 2012
This is version 69 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.