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Protein
Submitted name:

Integrin beta-1

Gene

ITGB1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

SignaLinkiQ5T3E6.

Names & Taxonomyi

Protein namesi
Submitted name:
Integrin beta-1Imported
Gene namesi
Name:ITGB1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

HGNCiHGNC:6153. ITGB1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000150093.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500426192421 – 136Sequence analysisAdd BLAST116

Proteomic databases

MaxQBiQ5T3E6.
PaxDbiQ5T3E6.
PeptideAtlasiQ5T3E6.
PRIDEiQ5T3E6.

Expressioni

Gene expression databases

BgeeiENSG00000150093.
ExpressionAtlasiQ5T3E6. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000303351.

Structurei

3D structure databases

ProteinModelPortaliQ5T3E6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 76PSIInterPro annotationAdd BLAST51

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1226. Eukaryota.
ENOG410XP60. LUCA.
GeneTreeiENSGT00760000119064.
HOGENOMiHOG000252936.

Family and domain databases

InterProiIPR033760. Integin_beta_N.
IPR027071. Integrin_beta-1.
IPR015812. Integrin_bsu.
IPR016201. PSI.
[Graphical view]
PANTHERiPTHR10082. PTHR10082. 1 hit.
PTHR10082:SF28. PTHR10082:SF28. 1 hit.
PfamiPF17205. PSI_integrin. 1 hit.
[Graphical view]
PRINTSiPR01186. INTEGRINB.
SMARTiSM00423. PSI. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q5T3E6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLQPIFWIG LISSVCCVFA QTDENRCLKA NAKSCGECIQ AGPNCGWCTN
60 70 80 90 100
STFLQEGMPT SARCDDLEAL KKKGCPPDDI ENPRGSKDIK KNKNVTNRSK
110 120 130
GTAEKLKPED ITQIQPQQLV LRLRSGEPQT FTLKFK
Length:136
Mass (Da):15,105
Last modified:December 21, 2004 - v1
Checksum:i780C560B9A9CE3AF
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei136Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL365203 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000437302; ENSP00000398029; ENSG00000150093.
UCSCiuc057sqn.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL365203 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliQ5T3E6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000303351.

Proteomic databases

MaxQBiQ5T3E6.
PaxDbiQ5T3E6.
PeptideAtlasiQ5T3E6.
PRIDEiQ5T3E6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000437302; ENSP00000398029; ENSG00000150093.
UCSCiuc057sqn.1. human.

Organism-specific databases

HGNCiHGNC:6153. ITGB1.
OpenTargetsiENSG00000150093.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1226. Eukaryota.
ENOG410XP60. LUCA.
GeneTreeiENSGT00760000119064.
HOGENOMiHOG000252936.

Enzyme and pathway databases

SignaLinkiQ5T3E6.

Miscellaneous databases

ChiTaRSiITGB1. human.

Gene expression databases

BgeeiENSG00000150093.
ExpressionAtlasiQ5T3E6. baseline and differential.

Family and domain databases

InterProiIPR033760. Integin_beta_N.
IPR027071. Integrin_beta-1.
IPR015812. Integrin_bsu.
IPR016201. PSI.
[Graphical view]
PANTHERiPTHR10082. PTHR10082. 1 hit.
PTHR10082:SF28. PTHR10082:SF28. 1 hit.
PfamiPF17205. PSI_integrin. 1 hit.
[Graphical view]
PRINTSiPR01186. INTEGRINB.
SMARTiSM00423. PSI. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5T3E6_HUMAN
AccessioniPrimary (citable) accession number: Q5T3E6
Entry historyi
Integrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: November 30, 2016
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.