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Protein
Submitted name:

Integrin beta-1

Gene

ITGB1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

SignaLinkiQ5T3E6.

Names & Taxonomyi

Protein namesi
Submitted name:
Integrin beta-1Imported
Gene namesi
Name:ITGB1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiHostDB:ENSG00000150093.18.
HGNCiHGNC:6153. ITGB1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000150093.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500426192421 – 136Sequence analysisAdd BLAST116

Proteomic databases

MaxQBiQ5T3E6.
PeptideAtlasiQ5T3E6.
PRIDEiQ5T3E6.

Expressioni

Gene expression databases

BgeeiENSG00000150093.
ExpressionAtlasiQ5T3E6. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliQ5T3E6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 76PSIInterPro annotationAdd BLAST51

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1226. Eukaryota.
ENOG410XP60. LUCA.
GeneTreeiENSGT00760000119064.
HOGENOMiHOG000252936.

Family and domain databases

InterProiView protein in InterPro
IPR027071. Integrin_beta-1.
IPR033760. Integrin_beta_N.
IPR015812. Integrin_bsu.
IPR016201. PSI.
PANTHERiPTHR10082. PTHR10082. 1 hit.
PTHR10082:SF28. PTHR10082:SF28. 1 hit.
PfamiView protein in Pfam
PF17205. PSI_integrin. 1 hit.
PRINTSiPR01186. INTEGRINB.
SMARTiView protein in SMART
SM00423. PSI. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q5T3E6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLQPIFWIG LISSVCCVFA QTDENRCLKA NAKSCGECIQ AGPNCGWCTN
60 70 80 90 100
STFLQEGMPT SARCDDLEAL KKKGCPPDDI ENPRGSKDIK KNKNVTNRSK
110 120 130
GTAEKLKPED ITQIQPQQLV LRLRSGEPQT FTLKFK
Length:136
Mass (Da):15,105
Last modified:December 21, 2004 - v1
Checksum:i780C560B9A9CE3AF
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei136Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL365203 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000437302; ENSP00000398029; ENSG00000150093.
UCSCiuc057sqn.1. human.

Similar proteinsi

Entry informationi

Entry nameiQ5T3E6_HUMAN
AccessioniPrimary (citable) accession number: Q5T3E6
Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: March 28, 2018
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported