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Protein
Submitted name:

Integrin beta-1

Gene

ITGB1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

SignaLinkiQ5T3E5.

Names & Taxonomyi

Protein namesi
Submitted name:
Integrin beta-1Imported
Gene namesi
Name:ITGB1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiHostDB:ENSG00000150093.18.
HGNCiHGNC:6153. ITGB1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000150093.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500426273221 – 89Sequence analysisAdd BLAST69

Proteomic databases

MaxQBiQ5T3E5.
PaxDbiQ5T3E5.
PeptideAtlasiQ5T3E5.
PRIDEiQ5T3E5.

Expressioni

Gene expression databases

BgeeiENSG00000150093.
ExpressionAtlasiQ5T3E5. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliQ5T3E5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 76PSIInterPro annotationAdd BLAST51

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1226. Eukaryota.
ENOG410XP60. LUCA.
GeneTreeiENSGT00760000119064.

Family and domain databases

InterProiView protein in InterPro
IPR027071. Integrin_beta-1.
IPR033760. Integrin_beta_N.
IPR015812. Integrin_bsu.
IPR016201. PSI.
PANTHERiPTHR10082. PTHR10082. 1 hit.
PTHR10082:SF28. PTHR10082:SF28. 1 hit.
PfamiView protein in Pfam
PF17205. PSI_integrin. 1 hit.
PRINTSiPR01186. INTEGRINB.
SMARTiView protein in SMART
SM00423. PSI. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q5T3E5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLQPIFWIG LISSVCCVFA QTDENRCLKA NAKSCGECIQ AGPNCGWCTN
60 70 80
STFLQEGMPT SARCDDLEAL KKKGCPPDDI ENPRGSKDI
Length:89
Mass (Da):9,685
Last modified:December 21, 2004 - v1
Checksum:iB198F26FCFBA1DE7
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei89Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL365203 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000417122; ENSP00000404546; ENSG00000150093.
UCSCiuc057sqq.1. human.

Similar proteinsi

Entry informationi

Entry nameiQ5T3E5_HUMAN
AccessioniPrimary (citable) accession number: Q5T3E5
Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: October 25, 2017
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported