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Protein
Submitted name:

Integrin beta-1

Gene

ITGB1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Integrin beta-1Imported
Gene namesi
Name:ITGB1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiHostDB:ENSG00000150093.18
HGNCiHGNC:6153 ITGB1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000150093

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500426298721 – 49Sequence analysisAdd BLAST29

Proteomic databases

PeptideAtlasiQ5T3E4

Expressioni

Gene expression databases

BgeeiENSG00000150093
ExpressionAtlasiQ5T3E4 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliQ5T3E4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 49PSI_integrinInterPro annotationAdd BLAST25

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1226 Eukaryota
ENOG410XP60 LUCA
GeneTreeiENSGT00760000119064

Family and domain databases

InterProiView protein in InterPro
IPR027071 Integrin_beta-1
IPR033760 Integrin_beta_N
IPR015812 Integrin_bsu
PANTHERiPTHR10082 PTHR10082, 1 hit
PTHR10082:SF28 PTHR10082:SF28, 1 hit
PfamiView protein in Pfam
PF17205 PSI_integrin, 1 hit

Sequencei

Sequence statusi: Fragment.

Q5T3E4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40 
MNLQPIFWIG LISSVCCVFA QTDENRCLKA NAKSCGECIQ AGPNCGWCT
Length:49
Mass (Da):5,325
Last modified:December 21, 2004 - v1
Checksum:i75C953A947A48D37
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei49Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL365203 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000414670; ENSP00000400544; ENSG00000150093
UCSCiuc057squ.1 human

Similar proteinsi

Entry informationi

Entry nameiQ5T3E4_HUMAN
AccessioniPrimary (citable) accession number: Q5T3E4
Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: March 28, 2018
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health