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Protein
Submitted name:

Neurobeachin

Gene

NBEA

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
NeurobeachinImported
Submitted name:
Neurobeachin, isoform CRA_eImported
Gene namesi
Name:NBEAImported
ORF Names:hCG_2019985Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 13

Organism-specific databases

HGNCiHGNC:7648. NBEA.

PTM / Processingi

Proteomic databases

EPDiQ5T321.

Expressioni

Gene expression databases

ExpressionAtlasiQ5T321. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000383295.

Structurei

3D structure databases

SMRiQ5T321. Positions 2147-2560.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2271 – 2560290BEACHInterPro annotationAdd
BLAST
Domaini2855 – 293884WD_REPEATS_REGIONInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG1786. Eukaryota.
ENOG410XNQC. LUCA.
GeneTreeiENSGT00760000119083.
HOGENOMiHOG000082375.
HOVERGENiHBG012582.
OrthoDBiEOG7HTHG2.

Family and domain databases

Gene3Di1.10.1540.10. 1 hit.
2.130.10.10. 1 hit.
2.30.29.40. 1 hit.
2.60.120.200. 1 hit.
InterProiIPR016024. ARM-type_fold.
IPR000409. BEACH_dom.
IPR013320. ConA-like_dom.
IPR010508. DUF1088.
IPR031570. DUF4704.
IPR023362. PH-BEACH_dom.
IPR011993. PH_dom-like.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF02138. Beach. 1 hit.
PF06469. DUF1088. 1 hit.
PF15787. DUF4704. 1 hit.
PF14844. PH_BEACH. 1 hit.
[Graphical view]
SMARTiSM01026. Beach. 1 hit.
SM00320. WD40. 5 hits.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 2 hits.
SSF49899. SSF49899. 1 hit.
SSF50729. SSF50729. 1 hit.
SSF50978. SSF50978. 1 hit.
SSF81837. SSF81837. 1 hit.
PROSITEiPS50197. BEACH. 1 hit.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5T321-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASEKPGPGP GLEPQPVGLI AVGAAGGGGG GSGGGGTGGS GMGELRGASG
60 70 80 90 100
SGSVMLPAGM INPSVPIRNI RMKFAVLIGL IQVGEVSNRD IVETVLNLLV
110 120 130 140 150
GGEFDLEMNF IIQDAESITC MTELLEHCDV TCQAEIWSMF TAILRKSVRN
160 170 180 190 200
LQTSTEVGLI EQVLLKMSAV DDMIADLLVD MLGVLASYSI TVKELKLLFS
210 220 230 240 250
MLRGESGIWP RHAVKLLSVL NQMPQRHGPD TFFNFPGCSA AAIALPPIAK
260 270 280 290 300
WPYQNGFTLN TWFRMDPLNN INVDKDKPYL YCFRTSKGVG YSAHFVGNCL
310 320 330 340 350
IVTSLKSKGK GFQHCVKYDF QPRKWYMISI VHIYNRWRNS EIRCYVNGQL
360 370 380 390 400
VSYGDMAWHV NTNDSYDKCF LGSSETADAN RVFCGQLGAV YVFSEALNPA
410 420 430 440 450
QIFAIHQLGP GYKSTFKFKS ESDIHLAEHH KQVLYDGKLA SSIAFTYNAK
460 470 480 490 500
ATDAQLCLES SPKENASIFV HSPHALMLQD VKAIVTHSIH SAIHSIGGIQ
510 520 530 540 550
VLFPLFAQLD NRQLNDSQVE TTVCATLLAF LVELLKSSVA MQEQMLGGKG
560 570 580 590 600
FLVIGYLLEK SSRVHITRAV LEQFLSFAKY LDGLSHGAPL LKQLCDHILF
610 620 630 640 650
NPAIWIHTPA KVQLSLYTYL SAEFIGTATI YTTIRRVGTV LQLMHTLKYY
660 670 680 690 700
YWVINPADSS GITPKGLDGP RPSQKEIISL RAFMLLFLKQ LILKDRGVKE
710 720 730 740 750
DELQSILNYL LTMHEDENIH DVLQLLVALM SEHPASMIPA FDQRNGIRVI
760 770 780 790 800
YKLLASKSES IWVQALKVLG YFLKHLGHKR KVEIMHTHSL FTLLGERLML
810 820 830 840 850
HTNTVTVTTY NTLYEILTEQ VCTQVVHKPH PEPDSTVKIQ NPMILKVVAT
860 870 880 890 900
LLKNSTPSAE LMEVRRLFLS DMIKLFSNSR ENRRCLLQCS VWQDWMFSLG
910 920 930 940 950
YINPKNSEEQ KITEMVYNIF RILLYHAIKY EWGGWRVWVD TLSIAHSKVT
960 970 980 990 1000
YEAHKEYLAK MYEEYQRQEE ENIKKGKKGN VSTISGLSSQ TTGAKGGMEI
1010 1020 1030 1040 1050
REIEDLSQSQ SPESETDYPV STDTRDLLMS TKVSDDILGN SDRPGSGVHV
1060 1070 1080 1090 1100
EVHDLLVDIK AEKVEATEVK LDDMDLSPET LVGGENGALV EVESLLDNVY
1110 1120 1130 1140 1150
SAAVEKLQNN VHGSVGIIKK NEEKDNGPLI TLADEKEDLP NSSTSFLFDK
1160 1170 1180 1190 1200
IPKQEEKLLP ELSSNHIIPN IQDTQVHLGV SDDLGLLAHM TGSVDLTCTS
1210 1220 1230 1240 1250
SIIEEKEFKI HTTSDGMSSI SERDLASSTK GLEYAEMTAT TLETESSSSK
1260 1270 1280 1290 1300
IVPNIDAGSI ISDTERSDDG KESGKEIRKI QTTTTTQAVQ GRSITQQDRD
1310 1320 1330 1340 1350
LRVDLGFRGM PMTEEQRRQF SPGPRTTMFR IPEFKWSPMH QRLLTDLLFA
1360 1370 1380 1390 1400
LETDVHVWRS HSTKSVMDFV NSNENIIFVH NTIHLISQMV DNIIIACGGI
1410 1420 1430 1440 1450
LPLLSAATSP TTELENIEVT QGMSAETAVT FLSRLMAMVD VLVFASSLNF
1460 1470 1480 1490 1500
SEIEAEKNMS SGGLMRQCLR LVCCVAVRNC LECRQRQRDR GNKSSHGSSK
1510 1520 1530 1540 1550
PQEVPQSVTA TAASKTPLEN VPGNLSPIKD PDRLLQDVDI NRLRAVVFRD
1560 1570 1580 1590 1600
VDDSKQAQFL ALAVVYFISV LMVSKYRDIL EPQRETTRTG SQPGRNIRQE
1610 1620 1630 1640 1650
INSPTSTVVV IPSIPHPSLN HGFLAKLIPE QSFGHSFYKE TPAAFPDTIK
1660 1670 1680 1690 1700
EKETPTPGED IQVESSIPHT DSGIGEEQVA SILNGAELET STGPDAMSEL
1710 1720 1730 1740 1750
LSTLSSEVKK SQESLTENPS ETLKPATSIS SISQTKGINV KEILKSLVAA
1760 1770 1780 1790 1800
PVEIAECGPE PIPYPDPALK RETQAILPMQ FHSFDRSVVV PVKKPPPGSL
1810 1820 1830 1840 1850
AVTTVGATTA GSGLPTGSTS NIFAATGATP KSMINTTGAV DSGSSSSSSS
1860 1870 1880 1890 1900
SSFVNGATSK NLPAVQTVAP MPEDSAENMS ITAKLERALE KVAPLLREIF
1910 1920 1930 1940 1950
VDFAPFLSRT LLGSHGQELL IEGLVCMKSS TSVVELVMLL CSQEWQNSIQ
1960 1970 1980 1990 2000
KNAGLAFIEL INEGRLLCHA MKDHIVRVAN EAEFILNRQR AEDVHKHAEF
2010 2020 2030 2040 2050
ESQCAQYAAD RREEEKMCDH LISAAKHRDH VTANQLKQKI LNILTNKHGA
2060 2070 2080 2090 2100
WGAVSHSQLH DFWRLDYWED DLRRRRRFVR NAFGSTHAEA LLKAAIEYGT
2110 2120 2130 2140 2150
EEDVVKSKKT FRSQAIVNQN AETELMLEGD DDAVSLLQEK EIDNLAGPVV
2160 2170 2180 2190 2200
LSTPAQLIAP VVVAKGTLSI TTTEIYFEVD EDDSAFKKID TKVLAYTEGL
2210 2220 2230 2240 2250
HGKWMFSEIR AVFSRRYLLQ NTALEVFMAN RTSVMFNFPD QATVKKVVYS
2260 2270 2280 2290 2300
LPRVGVGTSY GLPQARRISL ATPRQLYKSS NMTQRWQRRE ISNFEYLMFL
2310 2320 2330 2340 2350
NTIAGRTYND LNQYPVFPWV LTNYESEELD LTLPGNFRDL SKPIGALNPK
2360 2370 2380 2390 2400
RAVFYAERYE TWEDDQSPPY HYNTHYSTAT STLSWLVRIE PFTTFFLNAN
2410 2420 2430 2440 2450
DGKFDHPDRT FSSVARSWRT SQRDTSDVKE LIPEFYYLPE MFVNSNGYNL
2460 2470 2480 2490 2500
GVREDEVVVN DVDLPPWAKK PEDFVRINRM ALESEFVSCQ LHQWIDLIFG
2510 2520 2530 2540 2550
YKQRGPEAVR ALNVFHYLTY EGSVNLDSIT DPVLREAMEA QIQNFGQTPS
2560 2570 2580 2590 2600
QLLIEPHPPR SSAMHLCFLP QSPLMFKDQM QQDVIMVLKF PSNSPVTHVA
2610 2620 2630 2640 2650
ANTLPHLTIP AVVTVTCSRL FAVNRWHNTV GLRGAPGYSL DQAHHLPIEM
2660 2670 2680 2690 2700
DPLIANNSGV NKRQITDLVD QSIQINAHCF VVTADNRYIL ICGFWDKSFR
2710 2720 2730 2740 2750
VYSTETGKLT QIVFGHWDVV TCLARSESYI GGDCYIVSGS RDATLLLWYW
2760 2770 2780 2790 2800
SGRHHIIGDN PNSSDYPAPR AVLTGHDHEV VCVSVCAELG LVISGAKEGP
2810 2820 2830 2840 2850
CLVHTITGDL LRALEGPENC LFPRLISVSS EGHCIIYYER GRFSNFSING
2860 2870 2880 2890 2900
KLLAQMEIND STRAILLSSD GQNLVTGGDN GVVEVWQACD FKQLYIYPGC
2910 2920 2930 2940
DAGIRAMDLS HDQRTLITGM ASGSIVAFNI DFNRWHYEHQ NRY
Length:2,943
Mass (Da):327,549
Last modified:February 5, 2008 - v1
Checksum:i154F518F5D9C2527
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei2943 – 29431Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL138690 Genomic DNA. No translation available.
AL139083 Genomic DNA. No translation available.
AL159160 Genomic DNA. No translation available.
AL161718 Genomic DNA. No translation available.
AL161902 Genomic DNA. No translation available.
AL356430 Genomic DNA. No translation available.
AL357083 Genomic DNA. No translation available.
AL390071 Genomic DNA. No translation available.
CH471075 Genomic DNA. Translation: EAX08545.1.
RefSeqiXP_006719869.1. XM_006719806.2.
UniGeneiHs.491172.

Genome annotation databases

EnsembliENST00000379939; ENSP00000369271; ENSG00000172915.
GeneIDi26960.
UCSCiuc021ric.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL138690 Genomic DNA. No translation available.
AL139083 Genomic DNA. No translation available.
AL159160 Genomic DNA. No translation available.
AL161718 Genomic DNA. No translation available.
AL161902 Genomic DNA. No translation available.
AL356430 Genomic DNA. No translation available.
AL357083 Genomic DNA. No translation available.
AL390071 Genomic DNA. No translation available.
CH471075 Genomic DNA. Translation: EAX08545.1.
RefSeqiXP_006719869.1. XM_006719806.2.
UniGeneiHs.491172.

3D structure databases

SMRiQ5T321. Positions 2147-2560.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000383295.

Proteomic databases

EPDiQ5T321.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000379939; ENSP00000369271; ENSG00000172915.
GeneIDi26960.
UCSCiuc021ric.2. human.

Organism-specific databases

CTDi26960.
HGNCiHGNC:7648. NBEA.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1786. Eukaryota.
ENOG410XNQC. LUCA.
GeneTreeiENSGT00760000119083.
HOGENOMiHOG000082375.
HOVERGENiHBG012582.
OrthoDBiEOG7HTHG2.

Miscellaneous databases

ChiTaRSiNBEA. human.
GenomeRNAii26960.

Gene expression databases

ExpressionAtlasiQ5T321. baseline and differential.

Family and domain databases

Gene3Di1.10.1540.10. 1 hit.
2.130.10.10. 1 hit.
2.30.29.40. 1 hit.
2.60.120.200. 1 hit.
InterProiIPR016024. ARM-type_fold.
IPR000409. BEACH_dom.
IPR013320. ConA-like_dom.
IPR010508. DUF1088.
IPR031570. DUF4704.
IPR023362. PH-BEACH_dom.
IPR011993. PH_dom-like.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF02138. Beach. 1 hit.
PF06469. DUF1088. 1 hit.
PF15787. DUF4704. 1 hit.
PF14844. PH_BEACH. 1 hit.
[Graphical view]
SMARTiSM01026. Beach. 1 hit.
SM00320. WD40. 5 hits.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 2 hits.
SSF49899. SSF49899. 1 hit.
SSF50729. SSF50729. 1 hit.
SSF50978. SSF50978. 1 hit.
SSF81837. SSF81837. 1 hit.
PROSITEiPS50197. BEACH. 1 hit.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The sequence of the human genome."
    Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D., Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q., Kodira C.D., Zheng X.H.
    , Chen L., Skupski M., Subramanian G., Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S., Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J., Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R., Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A., Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K., Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V., Brandon R., Cargill M., Chandramouliswaran I., Charlab R., Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K., Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z., Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A., Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V., Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B., Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J., Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C., Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L., Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S., Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A., Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D., Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L., Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N., Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S., Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F., Kline L., Koduru S., Love A., Mann F., May D., McCawley S., McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K., Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M., Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C., Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N., Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M., Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F., Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A., Mi H., Lazareva B., Hatton T., Narechania A., Diemer K., Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R., Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J., Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H., Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D., Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A., Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S., Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L., Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W., McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M., Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J., Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E., Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X.
    Science 291:1304-1351(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "The DNA sequence and analysis of human chromosome 13."
    Dunham A., Matthews L.H., Burton J., Ashurst J.L., Howe K.L., Ashcroft K.J., Beare D.M., Burford D.C., Hunt S.E., Griffiths-Jones S., Jones M.C., Keenan S.J., Oliver K., Scott C.E., Ainscough R., Almeida J.P., Ambrose K.D., Andrews D.T.
    , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Bannerjee R., Barlow K.F., Bates K., Beasley H., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burrill W., Carder C., Carter N.P., Chapman J.C., Clamp M.E., Clark S.Y., Clarke G., Clee C.M., Clegg S.C., Cobley V., Collins J.E., Corby N., Coville G.J., Deloukas P., Dhami P., Dunham I., Dunn M., Earthrowl M.E., Ellington A.G., Faulkner L., Frankish A.G., Frankland J., French L., Garner P., Garnett J., Gilbert J.G.R., Gilson C.J., Ghori J., Grafham D.V., Gribble S.M., Griffiths C., Hall R.E., Hammond S., Harley J.L., Hart E.A., Heath P.D., Howden P.J., Huckle E.J., Hunt P.J., Hunt A.R., Johnson C., Johnson D., Kay M., Kimberley A.M., King A., Laird G.K., Langford C.J., Lawlor S., Leongamornlert D.A., Lloyd D.M., Lloyd C., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., McLaren S.J., McMurray A., Milne S., Moore M.J.F., Nickerson T., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K.M., Rice C.M., Searle S., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Steward C.A., Sycamore N., Tester J., Thomas D.W., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Wilming L., Wray P.W., Wright M.W., Young L., Coulson A., Durbin R., Hubbard T., Sulston J.E., Beck S., Bentley D.R., Rogers J., Ross M.T.
    Nature 428:522-528(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. Cited for: NUCLEOTIDE SEQUENCE.
  4. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  5. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiQ5T321_HUMAN
AccessioniPrimary (citable) accession number: Q5T321
Entry historyi
Integrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: June 8, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.