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Protein

Cyclin-Y-like protein 2

Gene

CCNYL2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionCyclin

Names & Taxonomyi

Protein namesi
Recommended name:
Cyclin-Y-like protein 2
Gene namesi
Name:CCNYL2
Synonyms:C10orf21
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:23495. CCNYL2.

Pathology & Biotechi

Polymorphism and mutation databases

DMDMi162416272.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003118161 – 361Cyclin-Y-like protein 2Add BLAST361

Proteomic databases

MaxQBiQ5T2Q4.
PaxDbiQ5T2Q4.
PeptideAtlasiQ5T2Q4.
PRIDEiQ5T2Q4.

PTM databases

iPTMnetiQ5T2Q4.
PhosphoSitePlusiQ5T2Q4.

Expressioni

Gene expression databases

CleanExiHS_CCNYL2.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ5T2Q4.
SMRiQ5T2Q4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini204 – 286Cyclin N-terminalAdd BLAST83

Sequence similaritiesi

Belongs to the cyclin family. Cyclin Y subfamily.Curated

Phylogenomic databases

eggNOGiKOG1675. Eukaryota.
ENOG410XNQX. LUCA.
HOGENOMiHOG000021397.
HOVERGENiHBG058985.
InParanoidiQ5T2Q4.
PhylomeDBiQ5T2Q4.
TreeFamiTF314464.

Family and domain databases

Gene3Di1.10.472.10. 1 hit.
InterProiView protein in InterPro
IPR013763. Cyclin-like.
IPR036915. Cyclin-like_sf.
IPR013922. Cyclin_PHO80-like.
IPR012399. Cyclin_Y.
PfamiView protein in Pfam
PF08613. Cyclin. 1 hit.
PIRSFiPIRSF028934. Cyclin_CG14939. 1 hit.
SMARTiView protein in SMART
SM00385. CYCLIN. 1 hit.
SUPFAMiSSF47954. SSF47954. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5T2Q4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGNILTCCVC PRASPGLHQH QGLVCHCESE IYEAAAGDLI AGVPVAAAVE
60 70 80 90 100
PGEVTFVAGE GLHMHHICER EMPEDIPLEP NPSDHPKAST IFLRKSQTDV
110 120 130 140 150
QEKKKKQLCK VSTEHFTQQY SSCSTIFLDD SIASQPHLTM TLKSCDLGTI
160 170 180 190 200
LSYQAKRDAH RSLGIFDEQL HPLTVRKEVL EEYFKYDPEH KLIFRFVRTL
210 220 230 240 250
FKAMRLTAEF AIVSLIYIER LVSYADIDIC PTNWKRIVLG AILLASKVWS
260 270 280 290 300
DMAVWNEDYC KLFKNITVEE MNELERQFLK LINYNNSITN SVYSRFYFDL
310 320 330 340 350
RTLAHNNGLY SPVYLLDRER AWKLEAFSRM EQDKVFYSAA KNGSLSADDL
360
IHLQRAKAIL F
Length:361
Mass (Da):41,278
Last modified:December 4, 2007 - v2
Checksum:i03CA99A71832235A
GO

Sequence cautioni

The sequence CAI12446 differs from that shown. Reason: Erroneous gene model prediction.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_03729757V → E. Corresponds to variant dbSNP:rs2490085Ensembl.1
Natural variantiVAR_037298176R → Q. Corresponds to variant dbSNP:rs2489720Ensembl.1
Natural variantiVAR_037299288I → V. Corresponds to variant dbSNP:rs2505861Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL391099 Genomic DNA. Translation: CAI12446.1. Sequence problems.
UniGeneiHs.568048.

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiCCYL2_HUMAN
AccessioniPrimary (citable) accession number: Q5T2Q4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: December 4, 2007
Last modified: October 25, 2017
This is version 95 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families