##gff-version 3
Q5T2D3	UniProtKB	Chain	1	398	.	.	.	ID=PRO_0000058103;Note=OTU domain-containing protein 3	
Q5T2D3	UniProtKB	Domain	65	189	.	.	.	Note=OTU;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00139	
Q5T2D3	UniProtKB	Domain	230	270	.	.	.	Note=UBA-like	
Q5T2D3	UniProtKB	Region	1	50	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q5T2D3	UniProtKB	Region	70	76	.	.	.	Note=Cys-loop	
Q5T2D3	UniProtKB	Region	127	137	.	.	.	Note=Variable-loop	
Q5T2D3	UniProtKB	Region	177	182	.	.	.	Note=His-loop	
Q5T2D3	UniProtKB	Region	305	383	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q5T2D3	UniProtKB	Compositional bias	14	45	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q5T2D3	UniProtKB	Compositional bias	313	345	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q5T2D3	UniProtKB	Compositional bias	346	380	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q5T2D3	UniProtKB	Active site	73	73	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q96FW1	
Q5T2D3	UniProtKB	Active site	76	76	.	.	.	Note=Nucleophile;Ontology_term=ECO:0000305;evidence=ECO:0000305|PubMed:32011234;Dbxref=PMID:32011234	
Q5T2D3	UniProtKB	Active site	182	182	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q5VVQ6	
Q5T2D3	UniProtKB	Modified residue	66	66	.	.	.	Note=N6-acetyllysine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:35675826;Dbxref=PMID:35675826	
Q5T2D3	UniProtKB	Modified residue	105	105	.	.	.	Note=N6-acetyllysine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:35675826;Dbxref=PMID:35675826	
Q5T2D3	UniProtKB	Modified residue	122	122	.	.	.	Note=N6-acetyllysine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:35675826;Dbxref=PMID:35675826	
Q5T2D3	UniProtKB	Modified residue	129	129	.	.	.	Note=N6-acetyllysine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:35675826;Dbxref=PMID:35675826	
Q5T2D3	UniProtKB	Modified residue	220	220	.	.	.	Note=N6-acetyllysine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:35675826;Dbxref=PMID:35675826	
Q5T2D3	UniProtKB	Modified residue	224	224	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:23186163;Dbxref=PMID:23186163	
Q5T2D3	UniProtKB	Modified residue	292	292	.	.	.	Note=N6-acetyllysine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:35675826;Dbxref=PMID:35675826	
Q5T2D3	UniProtKB	Modified residue	322	322	.	.	.	Note=N6-acetyllysine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:35675826;Dbxref=PMID:35675826	
Q5T2D3	UniProtKB	Natural variant	288	288	.	.	.	ID=VAR_087061;Note=Found in a family with an early age of onset of diabetes%3B uncertain significance%3B reduced the stability and catalytic activity. G->D;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:35675826;Dbxref=PMID:35675826	
Q5T2D3	UniProtKB	Natural variant	321	321	.	.	.	ID=VAR_051258;Note=N->S;Dbxref=dbSNP:rs2298110	
Q5T2D3	UniProtKB	Natural variant	333	333	.	.	.	ID=VAR_051259;Note=A->T;Dbxref=dbSNP:rs10916668	
Q5T2D3	UniProtKB	Mutagenesis	76	76	.	.	.	Note=Abolished deubiquitinase activity. C->S;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:32011234;Dbxref=PMID:32011234	
Q5T2D3	UniProtKB	Mutagenesis	178	181	.	.	.	Note=Impaired activity. RYGE->LSNG;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:23827681;Dbxref=PMID:23827681	
Q5T2D3	UniProtKB	Helix	56	62	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:4BOU	
Q5T2D3	UniProtKB	Beta strand	65	68	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:4BOU	
Q5T2D3	UniProtKB	Helix	76	86	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:4BOU	
Q5T2D3	UniProtKB	Beta strand	87	89	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:4BOU	
Q5T2D3	UniProtKB	Helix	92	105	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:4BOU	
Q5T2D3	UniProtKB	Helix	107	110	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:4BOU	
Q5T2D3	UniProtKB	Helix	111	113	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:4BOU	
Q5T2D3	UniProtKB	Helix	120	128	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:4BOU	
Q5T2D3	UniProtKB	Helix	136	145	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:4BOU	
Q5T2D3	UniProtKB	Beta strand	149	153	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:4BOU	
Q5T2D3	UniProtKB	Beta strand	160	166	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:4BOU	
Q5T2D3	UniProtKB	Beta strand	172	178	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:4BOU	
Q5T2D3	UniProtKB	Turn	179	181	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:4BOU	
Q5T2D3	UniProtKB	Beta strand	182	188	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:4BOU