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Protein
Submitted name:

Discoidin domain-containing receptor 2

Gene

DDR2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Discoidin domain-containing receptor 2Imported
Gene namesi
Name:DDR2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000162733.16.
HGNCiHGNC:2731. DDR2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000162733.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_500426224824 – 148Sequence analysisAdd BLAST125

Proteomic databases

MaxQBiQ5T244.
PaxDbiQ5T244.
PeptideAtlasiQ5T244.
PRIDEiQ5T244.

Expressioni

Gene expression databases

BgeeiENSG00000162733.
ExpressionAtlasiQ5T244. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliQ5T244.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini30 – 148F5/8 type CInterPro annotationAdd BLAST119

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1094. Eukaryota.
ENOG410XQAI. LUCA.
GeneTreeiENSGT00760000118818.
HOGENOMiHOG000197778.
HOVERGENiHBG105952.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
InterProiView protein in InterPro
IPR034299. DDR2.
IPR000421. FA58C.
IPR008979. Galactose-bd-like.
PANTHERiPTHR24416:SF394. PTHR24416:SF394. 1 hit.
PfamiView protein in Pfam
PF00754. F5_F8_type_C. 1 hit.
SMARTiView protein in SMART
SM00231. FA58C. 1 hit.
SUPFAMiSSF49785. SSF49785. 1 hit.
PROSITEiView protein in PROSITE
PS01285. FA58C_1. 1 hit.
PS50022. FA58C_3. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q5T244-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MILIPRMLLV LFLLLPILSS AKAQVNPAIC RYPLGMSGGQ IPDEDITASS
60 70 80 90 100
QWSESTAAKY GRLDSEEGDG AWCPEIPVEP DDLKEFLQID LHTLHFITLV
110 120 130 140
GTQGRHAGGH GIEFAPMYKI NYSRDGTRWI SWRNRHGKQV LDGNSNPY
Length:148
Mass (Da):16,521
Last modified:December 21, 2004 - v1
Checksum:iB2269EEB545D344D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei148Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL445197 Genomic DNA. No translation available.
AL596325 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000415555; ENSP00000391310; ENSG00000162733.
UCSCiuc057mva.1. human.

Similar proteinsi

Entry informationi

Entry nameiQ5T244_HUMAN
AccessioniPrimary (citable) accession number: Q5T244
Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: September 27, 2017
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported