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Q5T1Z0

- Q5T1Z0_HUMAN

UniProt

Q5T1Z0 - Q5T1Z0_HUMAN

Protein
Submitted name:

Phospholysine phosphohistidine inorganic pyrophosphate phosphatase

Gene

LHPP

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 69 (01 Oct 2014)
      Sequence version 1 (21 Dec 2004)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Phospholysine phosphohistidine inorganic pyrophosphate phosphataseImported
    Gene namesi
    Name:LHPPImported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 10

    Organism-specific databases

    HGNCiHGNC:30042. LHPP.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: HPA
    2. nucleus Source: HPA

    PTM / Processingi

    Proteomic databases

    PRIDEiQ5T1Z0.

    Expressioni

    Gene expression databases

    ArrayExpressiQ5T1Z0.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5T1Z0.
    SMRiQ5T1Z0. Positions 1-212.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000068106.
    HOVERGENiHBG075146.
    KOiK11725.
    OrthoDBiEOG7P2XT1.

    Family and domain databases

    Gene3Di3.40.50.1000. 2 hits.
    3.40.50.10410. 1 hit.
    InterProiIPR023214. HAD-like_dom.
    IPR006357. HAD-SF_hydro_IIA.
    IPR006355. HAD-SF_hydro_IIA_hyp2.
    IPR023215. NPhePase-like_dom.
    [Graphical view]
    PfamiPF13344. Hydrolase_6. 1 hit.
    [Graphical view]
    SUPFAMiSSF56784. SSF56784. 1 hit.
    TIGRFAMsiTIGR01458. HAD-SF-IIA-hyp3. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q5T1Z0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAPWGKRLAG VRGVLLDISG VLYDSGAGGG TAIAGSVEAV ARLKRSRLKV    50
    RFCTNESQKS RAELVGQLQR LGFDISEQEV TAPAPAACQI LKEQGLRPYL 100
    LIHDGVRSEF DQIDTSNPNC VVIADAGESF SYQNMNNAFQ VLMELEKPVL 150
    ISLGKGRYYK ETSGLMLDVG PYMKALEYAC GIKAEVVGKP SPEFFKSALQ 200
    AIGVEAHQLL SV 212
    Length:212
    Mass (Da):22,909
    Last modified:December 21, 2004 - v1
    Checksum:iABA1220A237C2D34
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL391708 Genomic DNA. No translation available.
    AL445237 Genomic DNA. No translation available.
    AL513190 Genomic DNA. No translation available.
    RefSeqiXP_005270084.1. XM_005270027.2.
    UniGeneiHs.527748.

    Genome annotation databases

    EnsembliENST00000392757; ENSP00000376512; ENSG00000107902.
    GeneIDi64077.
    KEGGihsa:64077.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL391708 Genomic DNA. No translation available.
    AL445237 Genomic DNA. No translation available.
    AL513190 Genomic DNA. No translation available.
    RefSeqi XP_005270084.1. XM_005270027.2.
    UniGenei Hs.527748.

    3D structure databases

    ProteinModelPortali Q5T1Z0.
    SMRi Q5T1Z0. Positions 1-212.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q5T1Z0.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000392757 ; ENSP00000376512 ; ENSG00000107902 .
    GeneIDi 64077.
    KEGGi hsa:64077.

    Organism-specific databases

    CTDi 64077.
    HGNCi HGNC:30042. LHPP.
    GenAtlasi Search...

    Phylogenomic databases

    HOGENOMi HOG000068106.
    HOVERGENi HBG075146.
    KOi K11725.
    OrthoDBi EOG7P2XT1.

    Miscellaneous databases

    GenomeRNAii 64077.

    Gene expression databases

    ArrayExpressi Q5T1Z0.

    Family and domain databases

    Gene3Di 3.40.50.1000. 2 hits.
    3.40.50.10410. 1 hit.
    InterProi IPR023214. HAD-like_dom.
    IPR006357. HAD-SF_hydro_IIA.
    IPR006355. HAD-SF_hydro_IIA_hyp2.
    IPR023215. NPhePase-like_dom.
    [Graphical view ]
    Pfami PF13344. Hydrolase_6. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56784. SSF56784. 1 hit.
    TIGRFAMsi TIGR01458. HAD-SF-IIA-hyp3. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence and comparative analysis of human chromosome 10."
      Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J.
      , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.
      Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiQ5T1Z0_HUMAN
    AccessioniPrimary (citable) accession number: Q5T1Z0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 21, 2004
    Last sequence update: December 21, 2004
    Last modified: October 1, 2014
    This is version 69 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3