SHC1

Functionⁱ

GO - Biological processⁱ

angiogenesis Source: InterPro
intracellular signal transduction Source: InterPro

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: SHC-transforming protein 1Imported Automatic assertion inferred from database entriesⁱ Ensembl:ENSP00000404908
Gene namesⁱ	Name:SHC1Imported Automatic assertion inferred from database entriesⁱ Ensembl:ENSP00000404908
Organismⁱ	Homo sapiens (Human)Imported Automatic assertion inferred from database entriesⁱ Ensembl:ENSP00000404908 Proteomes:UP000005640
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 1

Organism-specific databases

HGNCⁱ

HGNC:10840. SHC1.

Subcellular locationⁱ

GO - Cellular componentⁱ

intracellular Source: GOC

Complete GO annotation...

PTM / Processingⁱ

Proteomic databases

EPDⁱ	Q5T188.
MaxQBⁱ	Q5T188.
PeptideAtlasⁱ	Q5T188.
PRIDEⁱ	Q5T188.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000160691.
ExpressionAtlasⁱ	Q5T188. baseline and differential.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q5T188.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	Length	Description	Graphical view	Feature identifier	Actions
Domainⁱ	24 – 92	69	PIDInterPro annotation Automatic assertion inferred from signature matchⁱ PROSITE:PS01179			Add BLAST

Phylogenomic databases

GeneTreeⁱ	ENSGT00390000018860.
HOGENOMⁱ	HOG000231974.
HOVERGENⁱ	HBG050121.

Family and domain databases

Gene3Dⁱ	2.30.29.30. 1 hit.
InterProⁱ	IPR011993. PH_dom-like. IPR006019. PID_Shc-like. IPR006020. PTB/PI_dom. IPR029586. Shc1/ShcA. [Graphical view]
PANTHERⁱ	PTHR10337:SF2. PTHR10337:SF2. 1 hit.
Pfamⁱ	PF00640. PID. 1 hit. [Graphical view]
PRINTSⁱ	PR00629. SHCPIDOMAIN.
SUPFAMⁱ	SSF50729. SSF50729. 1 hit.
PROSITEⁱ	PS01179. PID. 1 hit. [Graphical view]

Sequenceⁱ

Sequence statusⁱ: Fragment.

Q5T188-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MPITLTVSTS SLNLMAADCK QDTAEYVAYV AKDPVNQRAC HILECPEGLA 
        60         70         80         90        100
QDVISTIGQA FELRFKQYLR NPPKLVTPHD RMAGFDGSAW DEEEEEPPDH 
       110        120        130        140        150
QYYNDFPGKE PPLGGVVDMR LREGAAPGAA RPTAPNAQTP SHLGATLPVG 
       160        170        180        190        200
QPVGGDPEVR KQMPPPPPCP AGRELFDDPS YVNVQNLDKA RQAVGGAGPP

Length:200

Mass (Da):21,522

Last modified:December 21, 2004 - v1

Checksum:ⁱF756CF32004F8E23

GO

Experimental Info

Feature key	Position(s)	Length	Description	Graphical view	Feature identifier	Actions
Non-terminal residueⁱ	200 – 200	1	Imported Automatic assertion inferred from database entriesⁱ Ensembl:ENSP00000404908

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL451085 Genomic DNA. No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AL451085 Genomic DNA. No translation available.

Genome annotation databases

Ensemblⁱ	ENST00000414115; ENSP00000404908; ENSG00000160691.
UCSCⁱ	uc057ljo.1. human.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL451085 Genomic DNA. No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AL451085 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortalⁱ	Q5T188.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

EPDⁱ	Q5T188.
MaxQBⁱ	Q5T188.
PeptideAtlasⁱ	Q5T188.
PRIDEⁱ	Q5T188.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000414115; ENSP00000404908; ENSG00000160691.
UCSCⁱ	uc057ljo.1. human.

Organism-specific databases

HGNCⁱ	HGNC:10840. SHC1.
GenAtlasⁱ	Search...

Phylogenomic databases

GeneTreeⁱ	ENSGT00390000018860.
HOGENOMⁱ	HOG000231974.
HOVERGENⁱ	HBG050121.

Miscellaneous databases

ChiTaRSⁱ	SHC1. human.

ChiTaRSⁱ

SHC1. human.

Gene expression databases

Bgeeⁱ	ENSG00000160691.
ExpressionAtlasⁱ	Q5T188. baseline and differential.

Family and domain databases

Gene3Dⁱ	2.30.29.30. 1 hit.
InterProⁱ	IPR011993. PH_dom-like. IPR006019. PID_Shc-like. IPR006020. PTB/PI_dom. IPR029586. Shc1/ShcA. [Graphical view]
PANTHERⁱ	PTHR10337:SF2. PTHR10337:SF2. 1 hit.
Pfamⁱ	PF00640. PID. 1 hit. [Graphical view]
PRINTSⁱ	PR00629. SHCPIDOMAIN.
SUPFAMⁱ	SSF50729. SSF50729. 1 hit.
PROSITEⁱ	PS01179. PID. 1 hit. [Graphical view]
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ

Q5T188_HUMAN

Accessionⁱ

Primary (citable) accession number: Q5T188

Entry historyⁱ

Integrated into UniProtKB/TrEMBL:	December 21, 2004
Last sequence update:	December 21, 2004
Last modified:	September 7, 2016
This is version 78 of the entry and version 1 of the sequence. [Complete history]

Entry statusⁱ

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q5T188 (Q5T188_HUMAN)

UniProt

Q5T188 - Q5T188_HUMAN

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SHC-transforming protein 1

Select a section on the left to see content.

<p>Provides any useful information about the protein, mostly biological knowledge.</p><p><a href='../manual/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>Provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.</p><p><a href='../manual/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>Provides information on the location and the topology of the mature protein in the cell.</p><p><a href='../manual/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>Describes post-translational modifications (PTMs) and/or processing events.</p><p><a href='../manual/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>Provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.</p><p><a href='../manual/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>Provides information on the tertiary and secondary structure of a protein.</p><p><a href='../manual/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>Provides information on sequence similarities with other proteins and the domain(s) present in a protein.</p><p><a href='../manual/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>Displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.</p><p><a href='../manual/sequences_section' target='_top'>More...</a></p>Sequencei

Experimental Info

Sequence databases

Genome annotation databases

<p>Is used to point to information related to entries and found in data collections other than UniProtKB.</p><p><a href='../manual/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>Provides general information on the entry.</p><p><a href='../manual/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>Contains any relevant information that doesn’t fit in any other defined sections</p><p><a href='../manual/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Caution

Functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Expressionⁱ

Structureⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ