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Protein
Submitted name:

SHC-transforming protein 1

Gene

SHC1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
SHC-transforming protein 1Imported
Gene namesi
Name:SHC1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

HGNCiHGNC:10840. SHC1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000160691.

PTM / Processingi

Proteomic databases

PaxDbiQ5T187.
PeptideAtlasiQ5T187.
PRIDEiQ5T187.

Expressioni

Gene expression databases

BgeeiENSG00000160691.
ExpressionAtlasiQ5T187. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000401303.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 110PIDInterPro annotationAdd BLAST110

Phylogenomic databases

eggNOGiKOG3697. Eukaryota.
ENOG410XTJN. LUCA.
GeneTreeiENSGT00390000018860.
HOGENOMiHOG000231974.

Family and domain databases

Gene3Di2.30.29.30. 1 hit.
InterProiIPR011993. PH_dom-like.
IPR006019. PID_Shc-like.
IPR006020. PTB/PI_dom.
IPR029586. Shc1/ShcA.
[Graphical view]
PANTHERiPTHR10337:SF2. PTHR10337:SF2. 1 hit.
PfamiPF00640. PID. 1 hit.
[Graphical view]
PRINTSiPR00629. SHCPIDOMAIN.
SMARTiSM00462. PTB. 1 hit.
[Graphical view]
SUPFAMiSSF50729. SSF50729. 1 hit.
PROSITEiPS01179. PID. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q5T187-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPITLTVSTS SLNLMAADCK QIIANHHMQS ISFASGGDPD TAEYVAYVAK
60 70 80 90 100
DPVNQRACHI LECPEGLAQD VISTIGQAFE LRFKQYLRNP PKLVTPHDRM
110 120
AGFDGSAWDE EEEEPPDHQY YNDFPGKEP
Length:129
Mass (Da):14,367
Last modified:October 5, 2016 - v8
Checksum:i26C1B8C25CC99478
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei129Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL451085 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000444179; ENSP00000398864; ENSG00000160691.
UCSCiuc057ljp.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL451085 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000401303.

Proteomic databases

PaxDbiQ5T187.
PeptideAtlasiQ5T187.
PRIDEiQ5T187.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000444179; ENSP00000398864; ENSG00000160691.
UCSCiuc057ljp.1. human.

Organism-specific databases

HGNCiHGNC:10840. SHC1.
OpenTargetsiENSG00000160691.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3697. Eukaryota.
ENOG410XTJN. LUCA.
GeneTreeiENSGT00390000018860.
HOGENOMiHOG000231974.

Miscellaneous databases

ChiTaRSiSHC1. human.

Gene expression databases

BgeeiENSG00000160691.
ExpressionAtlasiQ5T187. baseline and differential.

Family and domain databases

Gene3Di2.30.29.30. 1 hit.
InterProiIPR011993. PH_dom-like.
IPR006019. PID_Shc-like.
IPR006020. PTB/PI_dom.
IPR029586. Shc1/ShcA.
[Graphical view]
PANTHERiPTHR10337:SF2. PTHR10337:SF2. 1 hit.
PfamiPF00640. PID. 1 hit.
[Graphical view]
PRINTSiPR00629. SHCPIDOMAIN.
SMARTiSM00462. PTB. 1 hit.
[Graphical view]
SUPFAMiSSF50729. SSF50729. 1 hit.
PROSITEiPS01179. PID. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5T187_HUMAN
AccessioniPrimary (citable) accession number: Q5T187
Entry historyi
Integrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: October 5, 2016
Last modified: November 2, 2016
This is version 86 of the entry and version 8 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.