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Protein

Cyclin-dependent kinases regulatory subunit

Gene

CKS1B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Keywords - Biological processi

Cell cycle, Cell divisionUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Cyclin-dependent kinases regulatory subunitUniRule annotation
Gene namesi
Name:CKS1BImported
ORF Names:hCG_1739274Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA38791.

PTM / Processingi

Proteomic databases

MaxQBiQ5T178.

Expressioni

Gene expression databases

BgeeiENSG00000173207.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000471505.

Structurei

3D structure databases

SMRiQ5T178. Positions 5-74.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CKS family.UniRule annotation

Phylogenomic databases

eggNOGiKOG3484. Eukaryota.
ENOG4111UAN. LUCA.
HOVERGENiHBG003626.
KOiK02219.
OMAiIPKNRLM.
OrthoDBiEOG091G18GQ.
PhylomeDBiQ5T178.

Family and domain databases

Gene3Di3.30.170.10. 1 hit.
InterProiIPR000789. Cyclin-dep_kinase_reg-sub.
[Graphical view]
PfamiPF01111. CKS. 1 hit.
[Graphical view]
PRINTSiPR00296. CYCLINKINASE.
SMARTiSM01084. CKS. 1 hit.
[Graphical view]
SUPFAMiSSF55637. SSF55637. 1 hit.
PROSITEiPS00944. CKS_1. 1 hit.
PS00945. CKS_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5T178-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHKQIYYSD KYDDEEFEYR HVMLPKDIAK LVPKTHLMSE SEWRNLGVQQ
60 70
SQGWVHYMIH EPEPHILLFR RPLPKKPKK
Length:79
Mass (Da):9,660
Last modified:May 10, 2005 - v1
Checksum:iE64207B140FA38D5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK311769 mRNA. Translation: BAG34712.1.
CH471121 Genomic DNA. Translation: EAW53164.1.
RefSeqiNP_001817.1. NM_001826.2.
UniGeneiHs.374378.

Genome annotation databases

GeneIDi1163.
KEGGihsa:1163.
UCSCiuc001fgb.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK311769 mRNA. Translation: BAG34712.1.
CH471121 Genomic DNA. Translation: EAW53164.1.
RefSeqiNP_001817.1. NM_001826.2.
UniGeneiHs.374378.

3D structure databases

SMRiQ5T178. Positions 5-74.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000471505.

Proteomic databases

MaxQBiQ5T178.

Protocols and materials databases

DNASUi1163.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1163.
KEGGihsa:1163.
UCSCiuc001fgb.4. human.

Organism-specific databases

CTDi1163.
PharmGKBiPA38791.

Phylogenomic databases

eggNOGiKOG3484. Eukaryota.
ENOG4111UAN. LUCA.
HOVERGENiHBG003626.
KOiK02219.
OMAiIPKNRLM.
OrthoDBiEOG091G18GQ.
PhylomeDBiQ5T178.

Miscellaneous databases

GenomeRNAii1163.

Gene expression databases

BgeeiENSG00000173207.

Family and domain databases

Gene3Di3.30.170.10. 1 hit.
InterProiIPR000789. Cyclin-dep_kinase_reg-sub.
[Graphical view]
PfamiPF01111. CKS. 1 hit.
[Graphical view]
PRINTSiPR00296. CYCLINKINASE.
SMARTiSM01084. CKS. 1 hit.
[Graphical view]
SUPFAMiSSF55637. SSF55637. 1 hit.
PROSITEiPS00944. CKS_1. 1 hit.
PS00945. CKS_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5T178_HUMAN
AccessioniPrimary (citable) accession number: Q5T178
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: September 7, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.