CKS1B

Functionⁱ

Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.UniRule annotation

GO - Molecular functionⁱ

cyclin-dependent protein serine/threonine kinase regulator activity Source: InterPro
kinase activity Source: UniProtKB-KW

GO - Biological processⁱ

cell cycle Source: UniProtKB-KW
cell division Source: UniProtKB-KW

Complete GO annotation...

Keywords - Molecular functionⁱ

KinaseImported, Transferase

Keywords - Biological processⁱ

Cell cycle, Cell divisionUniRule annotation

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Cyclin-dependent kinases regulatory subunitUniRule annotation Automatic assertion according to rulesⁱ RuleBase:RU311113
Gene namesⁱ	Name:CKS1BImported Automatic assertion inferred from database entriesⁱ EMBL:EAW53164.1 ORF Names:hCG_1739274Imported Automatic assertion inferred from database entriesⁱ EMBL:EAW53164.1
Organismⁱ	Homo sapiens (Human)Imported Automatic assertion inferred from database entriesⁱ EMBL:BAG34712.1
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Pathology & Biotechⁱ

Organism-specific databases

PharmGKBⁱ	PA38791.

PharmGKBⁱ

PA38791.

PTM / Processingⁱ

Proteomic databases

MaxQBⁱ	Q5T178.

MaxQBⁱ

Q5T178.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000173207.

Bgeeⁱ

ENSG00000173207.

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	9606.ENSP00000471505.

STRINGⁱ

9606.ENSP00000471505.

Structureⁱ

3D structure databases

SMRⁱ	Q5T178. Positions 5-74.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the CKS family.UniRule annotation

Phylogenomic databases

eggNOGⁱ	KOG3484. Eukaryota. ENOG4111UAN. LUCA.
HOVERGENⁱ	HBG003626.
KOⁱ	K02219.
OMAⁱ	IPKNRLM.
OrthoDBⁱ	EOG091G18GQ.
PhylomeDBⁱ	Q5T178.

Family and domain databases

Gene3Dⁱ	3.30.170.10. 1 hit.
InterProⁱ	IPR000789. Cyclin-dep_kinase_reg-sub. [Graphical view]
Pfamⁱ	PF01111. CKS. 1 hit. [Graphical view]
PRINTSⁱ	PR00296. CYCLINKINASE.
SMARTⁱ	SM01084. CKS. 1 hit. [Graphical view]
SUPFAMⁱ	SSF55637. SSF55637. 1 hit.
PROSITEⁱ	PS00944. CKS_1. 1 hit. PS00945. CKS_2. 1 hit. [Graphical view]

Sequenceⁱ

Sequence statusⁱ: Complete.

Q5T178-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSHKQIYYSD KYDDEEFEYR HVMLPKDIAK LVPKTHLMSE SEWRNLGVQQ 
        60         70 
SQGWVHYMIH EPEPHILLFR RPLPKKPKK

Length:79

Mass (Da):9,660

Last modified:May 10, 2005 - v1

Checksum:ⁱE64207B140FA38D5

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK311769 mRNA. Translation: BAG34712.1. CH471121 Genomic DNA. Translation: EAW53164.1.
RefSeqⁱ	NP_001817.1. NM_001826.2.
UniGeneⁱ	Hs.374378.

Genome annotation databases

GeneIDⁱ	1163.
KEGGⁱ	hsa:1163.
UCSCⁱ	uc001fgb.4. human.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK311769 mRNA. Translation: BAG34712.1. CH471121 Genomic DNA. Translation: EAW53164.1.
RefSeqⁱ	NP_001817.1. NM_001826.2.
UniGeneⁱ	Hs.374378.

3D structure databases

SMRⁱ	Q5T178. Positions 5-74.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	9606.ENSP00000471505.

STRINGⁱ

9606.ENSP00000471505.

Proteomic databases

MaxQBⁱ	Q5T178.

MaxQBⁱ

Q5T178.

Protocols and materials databases

DNASUⁱ	1163.
Structural Biology Knowledgebase	Search...

Genome annotation databases

GeneIDⁱ	1163.
KEGGⁱ	hsa:1163.
UCSCⁱ	uc001fgb.4. human.

Organism-specific databases

CTDⁱ	1163.
PharmGKBⁱ	PA38791.

Phylogenomic databases

eggNOGⁱ	KOG3484. Eukaryota. ENOG4111UAN. LUCA.
HOVERGENⁱ	HBG003626.
KOⁱ	K02219.
OMAⁱ	IPKNRLM.
OrthoDBⁱ	EOG091G18GQ.
PhylomeDBⁱ	Q5T178.

Miscellaneous databases

GenomeRNAiⁱ	1163.

GenomeRNAiⁱ

1163.

Gene expression databases

Bgeeⁱ	ENSG00000173207.

Bgeeⁱ

ENSG00000173207.

Family and domain databases

Gene3Dⁱ	3.30.170.10. 1 hit.
InterProⁱ	IPR000789. Cyclin-dep_kinase_reg-sub. [Graphical view]
Pfamⁱ	PF01111. CKS. 1 hit. [Graphical view]
PRINTSⁱ	PR00296. CYCLINKINASE.
SMARTⁱ	SM01084. CKS. 1 hit. [Graphical view]
SUPFAMⁱ	SSF55637. SSF55637. 1 hit.
PROSITEⁱ	PS00944. CKS_1. 1 hit. PS00945. CKS_2. 1 hit. [Graphical view]
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ

Q5T178_HUMAN

Accessionⁱ

Primary (citable) accession number: Q5T178

Entry historyⁱ

Integrated into UniProtKB/TrEMBL:	May 10, 2005
Last sequence update:	May 10, 2005
Last modified:	September 7, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]

Entry statusⁱ

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

UniProtKB

UniParc

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UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q5T178 (Q5T178_HUMAN)

UniProt

Q5T178 - Q5T178_HUMAN

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Cyclin-dependent kinases regulatory subunit

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<p>Provides any useful information about the protein, mostly biological knowledge.</p><p><a href='../manual/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>Provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.</p><p><a href='../manual/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>Provides information on the disease(s) and phenotype(s) associated with a protein.</p><p><a href='../manual/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>Describes post-translational modifications (PTMs) and/or processing events.</p><p><a href='../manual/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>Provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.</p><p><a href='../manual/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>Provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.</p><p><a href='../manual/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>Provides information on the tertiary and secondary structure of a protein.</p><p><a href='../manual/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>Provides information on sequence similarities with other proteins and the domain(s) present in a protein.</p><p><a href='../manual/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>Provides information about the sequence similarity with other proteins.</p><p><a href='../manual/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>Displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.</p><p><a href='../manual/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>Is used to point to information related to entries and found in data collections other than UniProtKB.</p><p><a href='../manual/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>Provides general information on the entry.</p><p><a href='../manual/entry_information_section' target='_top'>More...</a></p>Entry informationi

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ