UniProtKB - Q5T178 (Q5T178_HUMAN)
(max 400 entries)x
Your basket is currently empty. i
Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)
Protein
Cyclin-dependent kinases regulatory subunit
Gene
CKS1B
Organism
Homo sapiens (Human)
Status
Functioni
Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.UniRule annotation
GO - Molecular functioni
- cyclin-dependent protein serine/threonine kinase regulator activity Source: InterPro
- kinase activity Source: UniProtKB-KW
GO - Biological processi
- cell division Source: UniProtKB-UniRule
- cell proliferation Source: Ensembl
- mitotic cell cycle phase transition Source: Ensembl
- regulation of transcription, DNA-templated Source: Ensembl
Keywordsi
Molecular function | KinaseImported, Transferase |
Biological process | Cell cycle, Cell divisionUniRule annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Cyclin-dependent kinases regulatory subunitUniRule annotation |
Gene namesi | Name:CKS1BImported ORF Names:hCG_1739274Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000173207.12. |
Family & Domainsi
Sequence similaritiesi
Belongs to the CKS family.UniRule annotation
Phylogenomic databases
eggNOGi | KOG3484. Eukaryota. ENOG4111UAN. LUCA. |
HOVERGENi | HBG003626. |
KOi | K02219. |
OMAi | IHYSSRY. |
OrthoDBi | EOG091G18GQ. |
Family and domain databases
Gene3Di | 3.30.170.10. 1 hit. |
InterProi | View protein in InterPro IPR000789. Cyclin-dep_kinase_reg-sub. IPR036858. Cyclin-dep_kinase_reg-sub_sf. |
Pfami | View protein in Pfam PF01111. CKS. 1 hit. |
PRINTSi | PR00296. CYCLINKINASE. |
SMARTi | View protein in SMART SM01084. CKS. 1 hit. |
SUPFAMi | SSF55637. SSF55637. 1 hit. |
PROSITEi | View protein in PROSITE PS00944. CKS_1. 1 hit. PS00945. CKS_2. 1 hit. |
i Sequence
Sequence statusi: Complete.
Q5T178-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSHKQIYYSD KYDDEEFEYR HVMLPKDIAK LVPKTHLMSE SEWRNLGVQQ
60 70
SQGWVHYMIH EPEPHILLFR RPLPKKPKK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK311769 mRNA. Translation: BAG34712.1. CH471121 Genomic DNA. Translation: EAW53164.1. |
RefSeqi | NP_001817.1. NM_001826.2. |
UniGenei | Hs.374378. |
Genome annotation databases
GeneIDi | 1163. |
KEGGi | hsa:1163. |
UCSCi | uc001fgb.4. human. |
Similar proteinsi
Entry informationi
Entry namei | Q5T178_HUMAN | |
Accessioni | Q5T178Primary (citable) accession number: Q5T178 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 10, 2005 |
Last sequence update: | May 10, 2005 | |
Last modified: | March 28, 2018 | |
This is version 107 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |