CKS1B

Functionⁱ

Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.UniRule annotation

GO - Molecular functionⁱ

cyclin-dependent protein serine/threonine kinase regulator activity Source: InterPro
kinase activity Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

cell division Source: UniProtKB-UniRule
cell proliferation Source: Ensembl
mitotic cell cycle phase transition Source: Ensembl
regulation of transcription, DNA-templated Source: Ensembl

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	KinaseImported, Transferase
Biological process	Cell cycle, Cell divisionUniRule annotation

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Cyclin-dependent kinases regulatory subunitUniRule annotation
Gene namesⁱ	Name:CKS1BImported ORF Names:hCG_1739274Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000173207.12.

EuPathDBⁱ

HostDB:ENSG00000173207.12.

Pathology & Biotechⁱ

Organism-specific databases

PharmGKBⁱ	PA38791.

PharmGKBⁱ

PA38791.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000173207.

Bgeeⁱ

ENSG00000173207.

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the CKS family.UniRule annotation

Phylogenomic databases

eggNOGⁱ	KOG3484. Eukaryota. ENOG4111UAN. LUCA.
HOVERGENⁱ	HBG003626.
KEGG Orthology (KO) More...KOⁱ	K02219.
OMAⁱ	IHYSSRY.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G18GQ.

Family and domain databases

Gene3Dⁱ	3.30.170.10. 1 hit.
InterProⁱ	View protein in InterPro IPR000789. Cyclin-dep_kinase_reg-sub. IPR036858. Cyclin-dep_kinase_reg-sub_sf.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01111. CKS. 1 hit.
PRINTSⁱ	PR00296. CYCLINKINASE.
SMARTⁱ	View protein in SMART SM01084. CKS. 1 hit.
SUPFAMⁱ	SSF55637. SSF55637. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00944. CKS_1. 1 hit. PS00945. CKS_2. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q5T178-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSHKQIYYSD KYDDEEFEYR HVMLPKDIAK LVPKTHLMSE SEWRNLGVQQ 
        60         70 
SQGWVHYMIH EPEPHILLFR RPLPKKPKK

Length:79

Mass (Da):9,660

Last modified:May 10, 2005 - v1

Checksum:ⁱE64207B140FA38D5

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK311769 mRNA. Translation: BAG34712.1. CH471121 Genomic DNA. Translation: EAW53164.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_001817.1. NM_001826.2.
UniGeneⁱ	Hs.374378.

Genome annotation databases

GeneIDⁱ	1163.
KEGGⁱ	hsa:1163.
UCSC genome browser More...UCSCⁱ	uc001fgb.4. human.

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q5T178	P61024 Q0P5A5 P61025 H2Q059 F7IPH3 G7MDV2 A0A2K6NPU3 H2N5J4 G1LYC2 G3RC66 +28	Homo sapiens (Human) Bos taurus (Bovine) Mus musculus (Mouse) Pan troglodytes (Chimpanzee) Callithrix jacchus (White-tufted-ear marmoset) Macaca mulatta (Rhesus macaque) Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) Ailuropoda melanoleuca (Giant panda) Gorilla gorilla gorilla (Western lowland gorilla) And more	79	UniRef100_P61024	Cluster: Cyclin-dependent kinases regulatory subunit 1	39

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q5T178	P61024 Q0P5A5 P61025 H2Q059 F7IPH3 G7MDV2 A0A2K6NPU3 H2N5J4 G1LYC2 G3RC66 +28	Homo sapiens (Human) Bos taurus (Bovine) Mus musculus (Mouse) Pan troglodytes (Chimpanzee) Callithrix jacchus (White-tufted-ear marmoset) Macaca mulatta (Rhesus macaque) Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) Ailuropoda melanoleuca (Giant panda) Gorilla gorilla gorilla (Western lowland gorilla) And more	79	UniRef90_P61024	Cluster: Cyclin-dependent kinases regulatory subunit 1	39

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q5T178	P61024 Q0P5A5 P61025 H2Q059 F7IPH3 G7MDV2 A0A2K6NPU3 H2N5J4 G1LYC2 G3RC66 +53	Homo sapiens (Human) Bos taurus (Bovine) Mus musculus (Mouse) Pan troglodytes (Chimpanzee) Callithrix jacchus (White-tufted-ear marmoset) Macaca mulatta (Rhesus macaque) Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) Ailuropoda melanoleuca (Giant panda) Gorilla gorilla gorilla (Western lowland gorilla) And more	79	UniRef50_P61024	Cluster: Cyclin-dependent kinases regulatory subunit 1	64

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK311769 mRNA. Translation: BAG34712.1. CH471121 Genomic DNA. Translation: EAW53164.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_001817.1. NM_001826.2.
UniGeneⁱ	Hs.374378.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	1163.
Structural Biology Knowledgebase	Search...

Genome annotation databases

GeneIDⁱ	1163.
KEGGⁱ	hsa:1163.
UCSC genome browser More...UCSCⁱ	uc001fgb.4. human.

Organism-specific databases

CTDⁱ	1163.
EuPathDBⁱ	HostDB:ENSG00000173207.12.
PharmGKBⁱ	PA38791.

Phylogenomic databases

eggNOGⁱ	KOG3484. Eukaryota. ENOG4111UAN. LUCA.
HOVERGENⁱ	HBG003626.
KEGG Orthology (KO) More...KOⁱ	K02219.
OMAⁱ	IHYSSRY.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G18GQ.

Miscellaneous databases

ChiTaRSⁱ	CKS1B. human.
GenomeRNAiⁱ	1163.

Gene expression databases

Bgeeⁱ	ENSG00000173207.

Bgeeⁱ

ENSG00000173207.

Family and domain databases

Gene3Dⁱ	3.30.170.10. 1 hit.
InterProⁱ	View protein in InterPro IPR000789. Cyclin-dep_kinase_reg-sub. IPR036858. Cyclin-dep_kinase_reg-sub_sf.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01111. CKS. 1 hit.
PRINTSⁱ	PR00296. CYCLINKINASE.
SMARTⁱ	View protein in SMART SM01084. CKS. 1 hit.
SUPFAMⁱ	SSF55637. SSF55637. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00944. CKS_1. 1 hit. PS00945. CKS_2. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q5T178_HUMAN
Accessionⁱ	Q5T178Primary (citable) accession number: Q5T178
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	May 10, 2005
	Last sequence update:	May 10, 2005
	Last modified:	March 28, 2018
	This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

UniProtKB - Q5T178 (Q5T178_HUMAN)

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Cyclin-dependent kinases regulatory subunit

Select a section on the left to see content.

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Names & Taxonomyⁱ

Organism-specific databases

Pathology & Biotechⁱ

Organism-specific databases

Expressionⁱ

Gene expression databases

Family & Domainsⁱ

Sequence similaritiesⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

Entry informationⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q5T178 (Q5T178_HUMAN)

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Cyclin-dependent kinases regulatory subunit

CKS1B

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Pathology & Biotechⁱ

Expressionⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ