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Protein

Cyclin-dependent kinases regulatory subunit

Gene

CKS1B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseImported, Transferase
Biological processCell cycle, Cell divisionUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Cyclin-dependent kinases regulatory subunitUniRule annotation
Gene namesi
Name:CKS1BImported
ORF Names:hCG_1739274Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000173207.12.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA38791.

PTM / Processingi

Proteomic databases

MaxQBiQ5T178.

Expressioni

Gene expression databases

BgeeiENSG00000173207.
ExpressionAtlasiQ5T178. baseline and differential.

Structurei

3D structure databases

SMRiQ5T178.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CKS family.UniRule annotation

Phylogenomic databases

eggNOGiKOG3484. Eukaryota.
ENOG4111UAN. LUCA.
HOVERGENiHBG003626.
KOiK02219.
OMAiLMTENEW.
OrthoDBiEOG091G18GQ.

Family and domain databases

Gene3Di3.30.170.10. 1 hit.
InterProiView protein in InterPro
IPR000789. Cyclin-dep_kinase_reg-sub.
PfamiView protein in Pfam
PF01111. CKS. 1 hit.
PRINTSiPR00296. CYCLINKINASE.
SMARTiView protein in SMART
SM01084. CKS. 1 hit.
SUPFAMiSSF55637. SSF55637. 1 hit.
PROSITEiView protein in PROSITE
PS00944. CKS_1. 1 hit.
PS00945. CKS_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5T178-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHKQIYYSD KYDDEEFEYR HVMLPKDIAK LVPKTHLMSE SEWRNLGVQQ
60 70
SQGWVHYMIH EPEPHILLFR RPLPKKPKK
Length:79
Mass (Da):9,660
Last modified:May 10, 2005 - v1
Checksum:iE64207B140FA38D5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK311769 mRNA. Translation: BAG34712.1.
CH471121 Genomic DNA. Translation: EAW53164.1.
RefSeqiNP_001817.1. NM_001826.2.
UniGeneiHs.374378.

Genome annotation databases

GeneIDi1163.
KEGGihsa:1163.
UCSCiuc001fgb.4. human.

Similar proteinsi

Entry informationi

Entry nameiQ5T178_HUMAN
AccessioniPrimary (citable) accession number: Q5T178
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: September 27, 2017
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.