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Protein

UBX domain-containing protein 11

Gene

UBXN11

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

May be involved in the reorganization of actin cytoskeleton mediated by RND1, RND2 AND RND3. Promotes RHOA activation mediated by GNA12 and GNA13 (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
UBX domain-containing protein 11
Alternative name(s):
Colorectal tumor-associated antigen COA-1
Socius
UBX domain-containing protein 5
Gene namesi
Name:UBXN11
Synonyms:SOC, UBXD5
ORF Names:PP2243
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

HGNCiHGNC:30600. UBXN11.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162408338.

Polymorphism and mutation databases

BioMutaiUBXN11.
DMDMi146325810.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 520520UBX domain-containing protein 11PRO_0000284921Add
BLAST

Proteomic databases

PaxDbiQ5T124.
PeptideAtlasiQ5T124.
PRIDEiQ5T124.

PTM databases

iPTMnetiQ5T124.
PhosphoSiteiQ5T124.

Expressioni

Gene expression databases

BgeeiQ5T124.
ExpressionAtlasiQ5T124. baseline and differential.
GenevisibleiQ5T124. HS.

Organism-specific databases

HPAiHPA028600.
HPA031357.

Interactioni

Subunit structurei

Interacts with GNA12, GNA13, RND1, RND2 AND RND3.By similarity

Binary interactionsi

WithEntry#Exp.IntActNotes
AESQ081173EBI-746004,EBI-717810
C6orf165Q8IYR04EBI-746004,EBI-749051
EIF4EP067303EBI-746004,EBI-73440
EIF4E2O605733EBI-746004,EBI-398610
ENKD1Q9H0I23EBI-746004,EBI-744099
PRKAA1Q131313EBI-746004,EBI-1181405
PRKAB2O437413EBI-746004,EBI-1053424
PSMA1P257863EBI-746004,EBI-359352
RHOBTB3O949553EBI-746004,EBI-2367123
RNF213Q63HN8-63EBI-746004,EBI-10248548
SCNM1Q9BWG63EBI-746004,EBI-748391
SH2D4AQ9H7883EBI-746004,EBI-747035
TRAF2Q129335EBI-746004,EBI-355744
USHBP1Q8N6Y03EBI-746004,EBI-739895

GO - Molecular functioni

Protein-protein interaction databases

BioGridi124844. 34 interactions.
IntActiQ5T124. 17 interactions.
MINTiMINT-1193561.
STRINGi9606.ENSP00000363338.

Structurei

3D structure databases

ProteinModelPortaliQ5T124.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini230 – 29465SEPPROSITE-ProRule annotationAdd
BLAST
Domaini392 – 46978UBXPROSITE-ProRule annotationAdd
BLAST
Repeati487 – 49481
Repeati495 – 50282
Repeati503 – 51083

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni487 – 510243 X 8 AA tandem repeats of P-G-P-G-P-G-P-SAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili76 – 14974Sequence analysisAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi483 – 51937Pro-richAdd
BLAST

Sequence similaritiesi

Contains 1 SEP domain.PROSITE-ProRule annotation
Contains 1 UBX domain.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil, Repeat

Phylogenomic databases

eggNOGiKOG2086. Eukaryota.
ENOG410YGXU. LUCA.
GeneTreeiENSGT00390000010180.
HOVERGENiHBG105985.
InParanoidiQ5T124.
OMAiFVIRQGE.
OrthoDBiEOG7W41B6.
PhylomeDBiQ5T124.
TreeFamiTF329799.

Family and domain databases

InterProiIPR012989. SEP_domain.
IPR029071. Ubiquitin-rel_dom.
IPR001012. UBX_dom.
[Graphical view]
PfamiPF08059. SEP. 1 hit.
PF00789. UBX. 1 hit.
[Graphical view]
SUPFAMiSSF102848. SSF102848. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEiPS51399. SEP. 1 hit.
PS50033. UBX. 1 hit.
[Graphical view]

Sequences (8)i

Sequence statusi: Complete.

This entry describes 8 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q5T124-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MSSPLASLSK TRKVPLPSEP MNPGRRGIRI YGDEDEVDML SDGCGSEEKI
60 70 80 90 100
SVPSCYGGIG APVSRQVPAS HDSELMAFMT RKLWDLEQQV KAQTDEILSK
110 120 130 140 150
DQKIAALEDL VQTLRPHPAE ATLQRQEELE TMCVQLQRQV REMERFLSDY
160 170 180 190 200
GLQWVGEPMD QEDSESKTVS EHGERDWMTA KKFWKPGDSL APPEVDFDRL
210 220 230 240 250
LASLQDLSEL VVEGDTQVTP VPGGARLRTL EPIPLKLYRN GIMMFDGPFQ
260 270 280 290 300
PFYDPSTQRC LRDILDGFFP SELQRLYPNG VPFKVSDLRN QVYLEDGLDP
310 320 330 340 350
FPGEGRVVGR QLMHKALDRV EEHPGSRMTA EKFLNRLPKF VIRQGEVIDI
360 370 380 390 400
RGPIRDTLQN CCPLPARIQE IVVETPTLAA ERERSQESPN TPAPPLSMLR
410 420 430 440 450
IKSENGEQAF LLMMQPDNTI GDVRALLAQA RVMDASAFEI FSTFPPTLYQ
460 470 480 490 500
DDTLTLQAAG LVPKAALLLR ARRAPKSSLK FSPGPCPGPG PGPSPGPGPG
510 520
PSPGPGPGPS PCPGPSPSPQ
Length:520
Mass (Da):57,373
Last modified:May 1, 2007 - v2
Checksum:i8642DB07C023276E
GO
Isoform 2 (identifier: Q5T124-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     34-66: Missing.

Show »
Length:487
Mass (Da):53,976
Checksum:i6EC6574FF3D44CE8
GO
Isoform 3 (identifier: Q5T124-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     67-186: Missing.

Show »
Length:400
Mass (Da):43,272
Checksum:i7E9912421BC64AA9
GO
Isoform 4 (identifier: Q5T124-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-38: Missing.

Note: No experimental confirmation available.
Show »
Length:482
Mass (Da):53,192
Checksum:i6D512E3805F8F560
GO
Isoform 5 (identifier: Q5T124-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-312: Missing.

Show »
Length:208
Mass (Da):22,191
Checksum:i17B2577621F2E843
GO
Isoform 6 (identifier: Q5T124-6) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     286-324: SDLRNQVYLE...KALDRVEEHP → ISCSSNHTFG...SRCTPWGTPV
     325-520: Missing.

Show »
Length:324
Mass (Da):36,302
Checksum:i992910E8E88948D5
GO
Isoform 7 (identifier: Q5T124-7) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     34-66: Missing.
     286-324: SDLRNQVYLE...KALDRVEEHP → ISCSSNHTFG...SRCTPWGTPV
     325-520: Missing.

Show »
Length:291
Mass (Da):32,904
Checksum:i23B621EC61D566EA
GO
Isoform 8 (identifier: Q5T124-8) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-75: Missing.

Show »
Length:445
Mass (Da):49,445
Checksum:iBBAC87DB55A1A377
GO

Sequence cautioni

The sequence AAM74202.1 differs from that shown. Reason: Frameshift at position 190. Curated
The sequence AAQ15261.1 differs from that shown. Reason: Frameshift at position 390. Curated
The sequence CAI15828.1 differs from that shown. Reason: Erroneous gene model prediction. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti19 – 191E → G in CAH56155 (Ref. 2) Curated
Sequence conflicti103 – 1031K → M in BAC05024 (PubMed:14702039).Curated
Sequence conflicti240 – 2401N → D in BAC05024 (PubMed:14702039).Curated
Sequence conflicti320 – 3201V → L in AAQ15261 (PubMed:15498874).Curated
Sequence conflicti388 – 3881S → L in AAM74202 (Ref. 2) Curated
Sequence conflicti418 – 4181N → D in BAC04307 (PubMed:17974005).Curated

Polymorphismi

The number of repeats is polymorphic and varies from 1 to 4.3 Publications

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti165 – 1651E → G.
Corresponds to variant rs6695966 [ dbSNP | Ensembl ].
VAR_031860
Natural varianti312 – 3121L → R.2 Publications
Corresponds to variant rs4332350 [ dbSNP | Ensembl ].
VAR_031861
Natural varianti474 – 4741A → V.1 Publication
VAR_031862
Natural varianti486 – 4861C → CPGPGPGPS.1 Publication
VAR_031863
Natural varianti487 – 4948Missing .2 Publications
VAR_031864
Natural varianti488 – 50215Missing .
VAR_031865Add
BLAST
Natural varianti501 – 5011P → S.
Corresponds to variant rs17838088 [ dbSNP | Ensembl ].
VAR_052689
Natural varianti509 – 5091P → S.2 Publications
Corresponds to variant rs17838088 [ dbSNP | Ensembl ].
VAR_052690

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 312312Missing in isoform 5. 1 PublicationVSP_024771Add
BLAST
Alternative sequencei1 – 7575Missing in isoform 8. 2 PublicationsVSP_024772Add
BLAST
Alternative sequencei1 – 3838Missing in isoform 4. CuratedVSP_024773Add
BLAST
Alternative sequencei34 – 6633Missing in isoform 2 and isoform 7. 3 PublicationsVSP_024774Add
BLAST
Alternative sequencei67 – 186120Missing in isoform 3. 1 PublicationVSP_024775Add
BLAST
Alternative sequencei286 – 32439SDLRN…VEEHP → ISCSSNHTFGDFEGSGDTQP PQTPPILRGSRCTPWGTPV in isoform 6 and isoform 7. 2 PublicationsVSP_024776Add
BLAST
Alternative sequencei325 – 520196Missing in isoform 6 and isoform 7. 2 PublicationsVSP_024777Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF521017 mRNA. Translation: AAM74201.1.
AF521018 mRNA. Translation: AAM74202.1. Frameshift.
AF520989 mRNA. Translation: AAM76060.1.
CR749413 mRNA. Translation: CAH18255.1.
BX648412 mRNA. Translation: CAH56155.1.
AK093258 mRNA. Translation: BAC04112.1.
AK094198 mRNA. Translation: BAC04307.1.
AK097368 mRNA. Translation: BAC05024.1.
AF370425 mRNA. Translation: AAQ15261.1. Frameshift.
AL451139 Genomic DNA. Translation: CAI15828.1. Sequence problems.
AL451139 Genomic DNA. Translation: CAI15832.1.
AL451139 Genomic DNA. Translation: CAI15833.1.
AL451139 Genomic DNA. Translation: CAI15834.1.
AL451139 Genomic DNA. Translation: CAI15835.1.
AL451139 Genomic DNA. Translation: CAI15836.1.
AL451139 Genomic DNA. Translation: CAI15840.1.
AL451139 Genomic DNA. Translation: CAI15842.1.
CH471059 Genomic DNA. Translation: EAX07823.1.
CH471059 Genomic DNA. Translation: EAX07826.1.
BC038106 mRNA. Translation: AAH38106.1.
CCDSiCCDS41286.1. [Q5T124-2]
CCDS41287.1. [Q5T124-3]
CCDS41288.1. [Q5T124-1]
RefSeqiNP_001070730.1. NM_001077262.1. [Q5T124-3]
NP_663320.2. NM_145345.2. [Q5T124-2]
NP_892120.2. NM_183008.2. [Q5T124-1]
UniGeneiHs.145061.

Genome annotation databases

EnsembliENST00000314675; ENSP00000324721; ENSG00000158062. [Q5T124-3]
ENST00000357089; ENSP00000349601; ENSG00000158062. [Q5T124-2]
ENST00000374217; ENSP00000363334; ENSG00000158062. [Q5T124-2]
ENST00000374221; ENSP00000363338; ENSG00000158062. [Q5T124-1]
ENST00000374222; ENSP00000363339; ENSG00000158062. [Q5T124-1]
GeneIDi91544.
KEGGihsa:91544.
UCSCiuc001blw.4. human. [Q5T124-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF521017 mRNA. Translation: AAM74201.1.
AF521018 mRNA. Translation: AAM74202.1. Frameshift.
AF520989 mRNA. Translation: AAM76060.1.
CR749413 mRNA. Translation: CAH18255.1.
BX648412 mRNA. Translation: CAH56155.1.
AK093258 mRNA. Translation: BAC04112.1.
AK094198 mRNA. Translation: BAC04307.1.
AK097368 mRNA. Translation: BAC05024.1.
AF370425 mRNA. Translation: AAQ15261.1. Frameshift.
AL451139 Genomic DNA. Translation: CAI15828.1. Sequence problems.
AL451139 Genomic DNA. Translation: CAI15832.1.
AL451139 Genomic DNA. Translation: CAI15833.1.
AL451139 Genomic DNA. Translation: CAI15834.1.
AL451139 Genomic DNA. Translation: CAI15835.1.
AL451139 Genomic DNA. Translation: CAI15836.1.
AL451139 Genomic DNA. Translation: CAI15840.1.
AL451139 Genomic DNA. Translation: CAI15842.1.
CH471059 Genomic DNA. Translation: EAX07823.1.
CH471059 Genomic DNA. Translation: EAX07826.1.
BC038106 mRNA. Translation: AAH38106.1.
CCDSiCCDS41286.1. [Q5T124-2]
CCDS41287.1. [Q5T124-3]
CCDS41288.1. [Q5T124-1]
RefSeqiNP_001070730.1. NM_001077262.1. [Q5T124-3]
NP_663320.2. NM_145345.2. [Q5T124-2]
NP_892120.2. NM_183008.2. [Q5T124-1]
UniGeneiHs.145061.

3D structure databases

ProteinModelPortaliQ5T124.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi124844. 34 interactions.
IntActiQ5T124. 17 interactions.
MINTiMINT-1193561.
STRINGi9606.ENSP00000363338.

PTM databases

iPTMnetiQ5T124.
PhosphoSiteiQ5T124.

Polymorphism and mutation databases

BioMutaiUBXN11.
DMDMi146325810.

Proteomic databases

PaxDbiQ5T124.
PeptideAtlasiQ5T124.
PRIDEiQ5T124.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000314675; ENSP00000324721; ENSG00000158062. [Q5T124-3]
ENST00000357089; ENSP00000349601; ENSG00000158062. [Q5T124-2]
ENST00000374217; ENSP00000363334; ENSG00000158062. [Q5T124-2]
ENST00000374221; ENSP00000363338; ENSG00000158062. [Q5T124-1]
ENST00000374222; ENSP00000363339; ENSG00000158062. [Q5T124-1]
GeneIDi91544.
KEGGihsa:91544.
UCSCiuc001blw.4. human. [Q5T124-1]

Organism-specific databases

CTDi91544.
GeneCardsiUBXN11.
HGNCiHGNC:30600. UBXN11.
HPAiHPA028600.
HPA031357.
MIMi609151. gene.
neXtProtiNX_Q5T124.
PharmGKBiPA162408338.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2086. Eukaryota.
ENOG410YGXU. LUCA.
GeneTreeiENSGT00390000010180.
HOVERGENiHBG105985.
InParanoidiQ5T124.
OMAiFVIRQGE.
OrthoDBiEOG7W41B6.
PhylomeDBiQ5T124.
TreeFamiTF329799.

Miscellaneous databases

ChiTaRSiUBXN11. human.
GeneWikiiUBXD5.
GenomeRNAii91544.
PROiQ5T124.
SOURCEiSearch...

Gene expression databases

BgeeiQ5T124.
ExpressionAtlasiQ5T124. baseline and differential.
GenevisibleiQ5T124. HS.

Family and domain databases

InterProiIPR012989. SEP_domain.
IPR029071. Ubiquitin-rel_dom.
IPR001012. UBX_dom.
[Graphical view]
PfamiPF08059. SEP. 1 hit.
PF00789. UBX. 1 hit.
[Graphical view]
SUPFAMiSSF102848. SSF102848. 1 hit.
SSF54236. SSF54236. 1 hit.
PROSITEiPS51399. SEP. 1 hit.
PS50033. UBX. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Identification of a colorectal tumor-associated antigen (COA-1) recognized by CD4(+) T lymphocytes."
    Maccalli C., Li Y.F., El-Gamil M., Rosenberg S.A., Robbins P.F.
    Cancer Res. 63:6735-6743(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 8), VARIANT VAL-474.
    Tissue: Colon cancer.
  2. Cai Q., Yu L.
    Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 8), VARIANTS ARG-312; 487-PRO--SER-494 DEL; 488-PRO--SER-502 DEL AND SER-509.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 6 AND 7).
    Tissue: Small intestine.
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2 AND 3), VARIANTS ARG-312; PRO-GLY-PRO-GLY-PRO-GLY-PRO-SER-486 INS; 487-PRO--SER-494 DEL AND SER-509.
    Tissue: Synovium and Testis.
  5. "Large-scale cDNA transfection screening for genes related to cancer development and progression."
    Wan D., Gong Y., Qin W., Zhang P., Li J., Wei L., Zhou X., Li H., Qiu X., Zhong F., He L., Yu J., Yao G., Jiang H., Qian L., Yu Y., Shu H., Chen X.
    , Xu H., Guo M., Pan Z., Chen Y., Ge C., Yang S., Gu J.
    Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 5), VARIANT PRO-GLY-PRO-GLY-PRO-GLY-PRO-SER-486 INS.
  6. "The DNA sequence and biological annotation of human chromosome 1."
    Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
    , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
    Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  7. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  8. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 6).
    Tissue: Testis.
  9. "Socius is a novel Rnd GTPase-interacting protein involved in disassembly of actin stress fibers."
    Katoh H., Harada A., Mori K., Negishi M.
    Mol. Cell. Biol. 22:2952-2964(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiUBX11_HUMAN
AccessioniPrimary (citable) accession number: Q5T124
Secondary accession number(s): D3DPK6
, Q5T117, Q5T120, Q5T125, Q5T126, Q5T129, Q5T131, Q5T133, Q63HM6, Q71RB3, Q8IY27, Q8N1L6, Q8N9M4, Q8NA18, Q8NFE3, Q8NFE4, Q8NFE6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: May 1, 2007
Last modified: July 6, 2016
This is version 97 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.