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Protein
Submitted name:

Dystonin

Gene

DST

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionActin-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
DystoninImported
Gene namesi
Name:DSTImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiHostDB:ENSG00000151914.18
HGNCiHGNC:1090 DST

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei13 – 38HelicalSequence analysisAdd BLAST26

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000151914

PTM / Processingi

Proteomic databases

EPDiQ5T0V7
MaxQBiQ5T0V7
PeptideAtlasiQ5T0V7
PRIDEiQ5T0V7

Expressioni

Gene expression databases

BgeeiENSG00000151914
ExpressionAtlasiQ5T0V7 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ5T0V7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini213 – 316Calponin-homology (CH)InterPro annotationAdd BLAST104
Domaini329 – 430Calponin-homology (CH)InterPro annotationAdd BLAST102

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili637 – 657Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

GeneTreeiENSGT00760000119163
HOGENOMiHOG000049054
HOVERGENiHBG102439

Family and domain databases

CDDicd00014 CH, 2 hits
Gene3Di1.10.418.10, 2 hits
InterProiView protein in InterPro
IPR001589 Actinin_actin-bd_CS
IPR001715 CH-domain
IPR036872 CH_dom_sf
PfamiView protein in Pfam
PF00307 CH, 2 hits
SMARTiView protein in SMART
SM00033 CH, 2 hits
SUPFAMiSSF47576 SSF47576, 1 hit
PROSITEiView protein in PROSITE
PS00019 ACTININ_1, 1 hit
PS00020 ACTININ_2, 1 hit
PS50021 CH, 2 hits

Sequencei

Sequence statusi: Fragment.

Q5T0V7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIAAAFLVLL RPYSIQCALF LLLLLLGTIA TIVFFCCWHR KLQKGRHPMK
60 70 80 90 100
SVFSGRSRSR DAVLRSHHFR SEGFRASPRH LRRRVAAAAA ARLEEVKPVV
110 120 130 140 150
EVHHQSEQET SVRKRRIKKS SRVQPEFYHS VQGASIRRPS SGNASYRCSM
160 170 180 190 200
SSSADFSDED DFSQKSGSAS PAPGDTLPWN LPKHERSKRK IQGGSVLDPA
210 220 230 240 250
ERAVLRIADE RDKVQKKTFT KWINQHLMKV RKHVNDLYED LRDGHNLISL
260 270 280 290 300
LEVLSGDTLP REKGRMRFHR LQNVQIALDY LKRRQVKLVN IRNDDITDGN
310 320 330 340 350
PKLTLGLIWT IILHFQISDI HVTGESEDMS AKERLLLWTQ QATEGYAGIR
360 370 380 390 400
CENFTTCWRD GKLFNAIIHK YRPDLIDMNT VAVQSNLANL EHAFYVAEKI
410 420 430 440 450
GVIRLLDPED VDVSSPDEKS VITYVSSLYD AFPKVPEGGE GIGANDVEVK
460 470 480 490 500
WIEYQNMVNY LIQWIRHHVT TMSERTFPNN PVELKALYNQ YLQFKETEIP
510 520 530 540 550
PKETEKSKIK RLYKLLEIWI EFGRIKLLQG YHPNDIEKEW GKLIIAMLER
560 570 580 590 600
EKALRPEVER LEMLQQIANR VQRDSVICED KLILAGNALQ SDSKRLESGV
610 620 630 640 650
QFQNEAEIAG YILECENLLR QHVIDVQILI DGKYYQADQL VQRVAKLRDE
660 670 680
IMALRNECSS VYSKGRILTT EQTKLMISGI TQSLNSGFA
Length:689
Mass (Da):79,168
Last modified:December 21, 2004 - v1
Checksum:iD19F0648CC1BE121
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei689Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL096710 Genomic DNA No translation available.
AL137008 Genomic DNA No translation available.
AL512422 Genomic DNA No translation available.
AL512448 Genomic DNA No translation available.
AL590005 Genomic DNA No translation available.
AL590037 Genomic DNA No translation available.
KF458172 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000449297; ENSP00000393082; ENSG00000151914
UCSCiuc063pff.1 human

Similar proteinsi

Entry informationi

Entry nameiQ5T0V7_HUMAN
AccessioniPrimary (citable) accession number: Q5T0V7
Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: March 28, 2018
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health