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Protein

Annexin

Gene

ANXA11

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Calcium, Calcium/phospholipid-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
AnnexinUniRule annotation
Gene namesi
Name:ANXA11Imported
ORF Names:hCG_22492Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA24825.

Expressioni

Gene expression databases

BgeeiENSG00000122359.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000265447.

Family & Domainsi

Domaini

A pair of annexin repeats may form one binding site for calcium and phospholipid.UniRule annotation

Sequence similaritiesi

Belongs to the annexin family.UniRule annotation
Contains 4 annexin repeats.UniRule annotation

Keywords - Domaini

AnnexinUniRule annotationSAAS annotation, RepeatUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0819. Eukaryota.
ENOG410XPUN. LUCA.
HOVERGENiHBG061815.
KOiK17095.
OMAiDIRMEYK.
OrthoDBiEOG091G0H6H.

Family and domain databases

Gene3Di1.10.220.10. 4 hits.
InterProiIPR001464. Annexin.
IPR018502. Annexin_repeat.
IPR018252. Annexin_repeat_CS.
IPR008157. AnnexinXI.
[Graphical view]
PANTHERiPTHR10502:SF29. PTHR10502:SF29. 3 hits.
PfamiPF00191. Annexin. 4 hits.
[Graphical view]
PRINTSiPR00196. ANNEXIN.
PR01810. ANNEXINXI.
SMARTiSM00335. ANX. 4 hits.
[Graphical view]
PROSITEiPS00223. ANNEXIN. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5T0G8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSYPGYPPPP GGYPPAAPGG GPWGGAAYPP PPSMPPIGLD NVATYAGQFN
60 70 80 90 100
QDYLSGMAAN MSGTFGGANM PNLYPGAPGA GYPPVPPGGF GQPPSAQQPV
110 120 130 140 150
PPYGMYPPPG GNPPSRMPSY PPYPGAPVPG QPMPPPGQQP PGAYPGQPPV
160 170 180 190 200
TYPGQPPVPL PGQQQPVPSY PGYPGSGTVT PAVPPTQFGS RGTITDAPGF
210 220 230 240 250
DPLRDAEVLR KAMKGFGTDE QAIIDCLGSR SNKQRQQILL SFKTAYGKDL
260 270 280 290 300
IKDLKSELSG NFEKTILALM KTPVLFDIYE IKEAIKGVGT DEACLIEILA
310 320 330 340 350
SRSNEHIREL NRAYKAEFKK TLEEAIRSDT SGHFQRLLIS LSQGNRDEST
360 370 380 390 400
NVDMSLAQRD AQELYAAGEN RLGTDESKFN AVLCSRSRAH LVAVFNEYQR
410 420 430 440 450
MTGRDIEKSI CREMSGDLEE GMLAVVKCLK NTPAFFAERL NKAMRGAGTK
460 470 480 490 500
DRTLIRIMVS RSETDLLDIR SEYKRMYGKS LYHDISGDTS GDYRKILLKI

CGGND
Length:505
Mass (Da):54,390
Last modified:May 10, 2005 - v1
Checksum:i4ADCAC8F270BFEE4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK056107 mRNA. Translation: BAG51628.1.
AK126287 mRNA. Translation: BAG54303.1.
CH471142 Genomic DNA. Translation: EAW80400.1.
CH471142 Genomic DNA. Translation: EAW80401.1.
CH471142 Genomic DNA. Translation: EAW80402.1.
CH471142 Genomic DNA. Translation: EAW80403.1.
CH471142 Genomic DNA. Translation: EAW80404.1.
CH471142 Genomic DNA. Translation: EAW80405.1.
RefSeqiNP_001148.1. NM_001157.2.
NP_001265336.1. NM_001278407.1.
NP_001265337.1. NM_001278408.1.
NP_665875.1. NM_145868.1.
NP_665876.1. NM_145869.1.
XP_011538038.1. XM_011539736.2.
UniGeneiHs.530291.

Genome annotation databases

GeneIDi311.
KEGGihsa:311.
UCSCiuc001kbr.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK056107 mRNA. Translation: BAG51628.1.
AK126287 mRNA. Translation: BAG54303.1.
CH471142 Genomic DNA. Translation: EAW80400.1.
CH471142 Genomic DNA. Translation: EAW80401.1.
CH471142 Genomic DNA. Translation: EAW80402.1.
CH471142 Genomic DNA. Translation: EAW80403.1.
CH471142 Genomic DNA. Translation: EAW80404.1.
CH471142 Genomic DNA. Translation: EAW80405.1.
RefSeqiNP_001148.1. NM_001157.2.
NP_001265336.1. NM_001278407.1.
NP_001265337.1. NM_001278408.1.
NP_665875.1. NM_145868.1.
NP_665876.1. NM_145869.1.
XP_011538038.1. XM_011539736.2.
UniGeneiHs.530291.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000265447.

Protocols and materials databases

DNASUi311.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi311.
KEGGihsa:311.
UCSCiuc001kbr.2. human.

Organism-specific databases

CTDi311.
PharmGKBiPA24825.

Phylogenomic databases

eggNOGiKOG0819. Eukaryota.
ENOG410XPUN. LUCA.
HOVERGENiHBG061815.
KOiK17095.
OMAiDIRMEYK.
OrthoDBiEOG091G0H6H.

Miscellaneous databases

ChiTaRSiANXA11. human.
GenomeRNAii311.

Gene expression databases

BgeeiENSG00000122359.

Family and domain databases

Gene3Di1.10.220.10. 4 hits.
InterProiIPR001464. Annexin.
IPR018502. Annexin_repeat.
IPR018252. Annexin_repeat_CS.
IPR008157. AnnexinXI.
[Graphical view]
PANTHERiPTHR10502:SF29. PTHR10502:SF29. 3 hits.
PfamiPF00191. Annexin. 4 hits.
[Graphical view]
PRINTSiPR00196. ANNEXIN.
PR01810. ANNEXINXI.
SMARTiSM00335. ANX. 4 hits.
[Graphical view]
PROSITEiPS00223. ANNEXIN. 4 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5T0G8_HUMAN
AccessioniPrimary (citable) accession number: Q5T0G8
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: October 5, 2016
This is version 120 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.