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Protein

Protein RER1

Gene

RER1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Protein RER1UniRule annotation
Gene namesi
Name:RER1Imported
ORF Names:hCG_24604Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000157916.18

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei41 – 60HelicalSequence analysisAdd BLAST20
Transmembranei66 – 83HelicalSequence analysisAdd BLAST18
Transmembranei145 – 162HelicalSequence analysisAdd BLAST18

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134901074

Expressioni

Gene expression databases

BgeeiENSG00000157916

Interactioni

GO - Molecular functioni

Family & Domainsi

Sequence similaritiesi

Belongs to the RER1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1688 Eukaryota
COG5249 LUCA
HOVERGENiHBG002871
OMAiLPEWQFW

Family and domain databases

InterProiView protein in InterPro
IPR004932 Rer1
PANTHERiPTHR10743 PTHR10743, 1 hit
PfamiView protein in Pfam
PF03248 Rer1, 1 hit
PIRSFiPIRSF016013 AtER_Rer1p, 1 hit

Sequencei

Sequence statusi: Complete.

Q5T094-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEGDSVGES VHGKPSVVYR FFTRLGQIYQ SWLDKSTPYT AVRWVVTLGL
60 70 80 90 100
SFVYMIRVYL LQGWYIVTYA LGIYHLNLFI AFLSPKVDPS LMEDSDDGPS
110 120 130 140 150
LPTKQNEEFR PFIRRLPEFK FWHAATKGIL VAMVCTFFDA FNVPVFWPIL
160 170 180 190
VMYFIMLFCI TMKRQIKHMI KYRYIPFTHG KRRYRGKEDA GKAFAS
Length:196
Mass (Da):22,958
Last modified:May 10, 2005 - v1
Checksum:i0FF7F3CDC9F88A69
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT007224 mRNA Translation: AAP35888.1
AK289658 mRNA Translation: BAF82347.1
CH471183 Genomic DNA Translation: EAW56109.1
CH471183 Genomic DNA Translation: EAW56110.1
CH471183 Genomic DNA Translation: EAW56111.1
CH471183 Genomic DNA Translation: EAW56113.1
RefSeqiNP_008964.3, NM_007033.4
XP_006710369.1, XM_006710306.2
XP_011538844.1, XM_011540542.1
XP_011538845.1, XM_011540543.1
XP_016855622.1, XM_017000133.1
XP_016855623.1, XM_017000134.1
XP_016855624.1, XM_017000135.1
UniGeneiHs.525527

Genome annotation databases

GeneIDi11079
KEGGihsa:11079
UCSCiuc001aje.3 human

Similar proteinsi

Entry informationi

Entry nameiQ5T094_HUMAN
AccessioniPrimary (citable) accession number: Q5T094
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: April 25, 2018
This is version 116 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
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Main funding by: National Institutes of Health