Q5T036 (F120S_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative FAM120A opposite strand protein

Gene names

Name:	FAM120AOS
Synonyms:	C9orf10OS

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	256 AA.
Sequence status	Complete.
Protein existence	Uncertain

General annotation (Comments)

Caution

Product of a dubious gene prediction.

Ontologies

Keywords
Coding sequence diversity	Polymorphism
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 256	256	Putative FAM120A opposite strand protein		PRO_0000337248
Regions
	Compositional bias	31 – 117	87	Arg-rich
Natural variations
	Natural variant	22	1	L → F. Ref.1 Corresponds to variant rs1055710 [ dbSNP | Ensembl ].		VAR_043677
	Natural variant	241	1	K → E. Ref.1 Corresponds to variant rs10821128 [ dbSNP | Ensembl ].		VAR_043678

Sequences

	Sequence		Length	Mass (Da)
	Q5T036 [UniParc]. Last modified December 21, 2004. Version 1. Checksum: 1BEA53331BA94241	FASTA	256	27,929
	10 20 30 40 50 60 MGKTKDIGDD DTVASEFWSG ALSQPSSVPT RPRTPNRDSW RRAWAARGLH PRPSILQPGP 70 80 90 100 110 120 ARLSRARAGG TRCPQRRHGR ATFCALGRGI GVRRGPGPRP ARIPGLTLTW KRMSARRMQW 130 140 150 160 170 180 AMQTGGRNQT FGGGVPLFWT WLTICCAVWR SLPCRLTHSC SRAFSSAPLK KTKSSMLPPK 190 200 210 220 230 240 QALASAARNL CRGAGCNRQA VAGQLLPSTW SLHAHGLAKE APILPVKKIS RSCSVNNKVS 250 KKTTKPPTLR SFLSPI

References

[1]

"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANTS PHE-22 AND GLU-241.

[2]

"DNA sequence and analysis of human chromosome 9." Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L. , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I. Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK056096 mRNA. No translation available. AL583839, AL353629 Genomic DNA. Translation: CAI12342.1. AL353629, AL583839 Genomic DNA. Translation: CAI96107.1.
IPI	IPI00747666.
RefSeq	NP_942138.2. NM_198841.2.
UniGene	Hs.709859. Hs.741227.
3D structure databases
ProteinModelPortal	Q5T036.
ModBase	Search...
Proteomic databases
PaxDb	Q5T036.
PRIDE	Q5T036.
Protocols and materials databases
DNASU	158293.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000375412; ENSP00000364561; ENSG00000188938.
GeneID	158293.
KEGG	hsa:158293.
UCSC	uc004atu.4. human.
Organism-specific databases
CTD	158293.
GeneCards	GC09M096208.
HGNC	HGNC:23389. FAM120AOS.
HPA	HPA021475.
neXtProt	NX_Q5T036.
PharmGKB	PA134893278.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG115919.
HOGENOM	HOG000112432.
HOVERGEN	HBG101582.
InParanoid	Q5T036.
OMA	ASEFWSG.
PhylomeDB	Q5T036.
Gene expression databases
ArrayExpress	Q5T036.
Bgee	Q5T036.
CleanEx	HS_FAM120AOS.
Genevestigator	Q5T036.
Family and domain databases
ProtoNet	Search...
Other
ChiTaRS	FAM120AOS. human.
GenomeRNAi	158293.
NextBio	87677.

Entry information

Entry name

F120S_HUMAN

Accession

Primary (citable) accession number: Q5T036
Secondary accession number(s): A6NN20

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	December 21, 2004
Last modified:	April 3, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.