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Q5T036 (F120S_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative FAM120A opposite strand protein
Gene names
Name:FAM120AOS
Synonyms:C9orf10OS
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length256 AA.
Sequence statusComplete.
Protein existenceUncertain

General annotation (Comments)

Caution

Product of a dubious gene prediction.

Ontologies

Keywords
   Coding sequence diversityPolymorphism
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 256256Putative FAM120A opposite strand protein
PRO_0000337248

Regions

Compositional bias31 – 11787Arg-rich

Natural variations

Natural variant221L → F. Ref.1
Corresponds to variant rs1055710 [ dbSNP | Ensembl ].
VAR_043677
Natural variant2411K → E. Ref.1
Corresponds to variant rs10821128 [ dbSNP | Ensembl ].
VAR_043678

Sequences

Sequence LengthMass (Da)Tools
Q5T036 [UniParc].

Last modified December 21, 2004. Version 1.
Checksum: 1BEA53331BA94241

FASTA25627,929
        10         20         30         40         50         60 
MGKTKDIGDD DTVASEFWSG ALSQPSSVPT RPRTPNRDSW RRAWAARGLH PRPSILQPGP 

        70         80         90        100        110        120 
ARLSRARAGG TRCPQRRHGR ATFCALGRGI GVRRGPGPRP ARIPGLTLTW KRMSARRMQW 

       130        140        150        160        170        180 
AMQTGGRNQT FGGGVPLFWT WLTICCAVWR SLPCRLTHSC SRAFSSAPLK KTKSSMLPPK 

       190        200        210        220        230        240 
QALASAARNL CRGAGCNRQA VAGQLLPSTW SLHAHGLAKE APILPVKKIS RSCSVNNKVS 

       250 
KKTTKPPTLR SFLSPI 

« Hide

References

[1]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANTS PHE-22 AND GLU-241.
[2]"DNA sequence and analysis of human chromosome 9."
Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L. expand/collapse author list , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.
Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK056096 mRNA. No translation available.
AL583839, AL353629 Genomic DNA. Translation: CAI12342.1.
AL353629, AL583839 Genomic DNA. Translation: CAI96107.1.
CCDSCCDS6705.1.
RefSeqNP_942138.2. NM_198841.2.
UniGeneHs.350364.
Hs.709859.

3D structure databases

ProteinModelPortalQ5T036.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid127664. 1 interaction.

Proteomic databases

PaxDbQ5T036.
PRIDEQ5T036.

Protocols and materials databases

DNASU158293.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000375412; ENSP00000364561; ENSG00000188938.
GeneID158293.
KEGGhsa:158293.
UCSCuc004atu.4. human.

Organism-specific databases

CTD158293.
GeneCardsGC09M096208.
HGNCHGNC:23389. FAM120AOS.
HPAHPA021475.
neXtProtNX_Q5T036.
PharmGKBPA134893278.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG115919.
HOGENOMHOG000112432.
HOVERGENHBG101582.
InParanoidQ5T036.
OMAASEFWSG.
PhylomeDBQ5T036.
TreeFamTF338583.

Gene expression databases

ArrayExpressQ5T036.
BgeeQ5T036.
CleanExHS_FAM120AOS.
GenevestigatorQ5T036.

Family and domain databases

ProtoNetSearch...

Other

ChiTaRSFAM120AOS. human.
GenomeRNAi158293.
NextBio87677.

Entry information

Entry nameF120S_HUMAN
AccessionPrimary (citable) accession number: Q5T036
Secondary accession number(s): A6NN20
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: December 21, 2004
Last modified: July 9, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 9

Human chromosome 9: entries, gene names and cross-references to MIM