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Protein
Submitted name:

Retinal dehydrogenase 1

Gene

ALDH1A1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Retinal dehydrogenase 1Imported
Gene namesi
Name:ALDH1A1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

HGNCiHGNC:402. ALDH1A1.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000165092.

PTM / Processingi

Proteomic databases

MaxQBiQ5SYQ8.
PaxDbiQ5SYQ8.
PeptideAtlasiQ5SYQ8.
PRIDEiQ5SYQ8.

Expressioni

Gene expression databases

BgeeiENSG00000165092.
ExpressionAtlasiQ5SYQ8. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000297785.

Structurei

3D structure databases

ProteinModelPortaliQ5SYQ8.
SMRiQ5SYQ8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 237AldedhInterPro annotationAdd BLAST209

Phylogenomic databases

eggNOGiKOG2450. Eukaryota.
COG1012. LUCA.
GeneTreeiENSGT00760000118999.
HOGENOMiHOG000271516.
HOVERGENiHBG000097.

Family and domain databases

Gene3Di3.40.605.10. 1 hit.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMiSSF53720. SSF53720. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q5SYQ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSSGTPDLP VLLTDLKIQY TKIFINNEWH DSVSGKKFPV FNPATEEELC
60 70 80 90 100
QVEEGDKEDV DKAVKAARQA FQIGSPWRTM DASERGRLLY KLADLIERDR
110 120 130 140 150
LLLATMESMN GGKLYSNAYL NDLAGCIKTL RYCAGWADKI QGRTIPIDGN
160 170 180 190 200
FFTYTRHEPI GVCGQIIPWN FPLVMLIWKI GPALSCGNTV VVKPAEQTPL
210 220 230
TALHVASLIK EAGFPPGVVN IVPGYGPTAG AAISSHMD
Length:238
Mass (Da):26,097
Last modified:December 21, 2004 - v1
Checksum:iDC6ACA7F7E8897D3
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei238Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL359997 Genomic DNA. No translation available.
AL591031 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000419959; ENSP00000388026; ENSG00000165092.
UCSCiuc064ttb.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL359997 Genomic DNA. No translation available.
AL591031 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliQ5SYQ8.
SMRiQ5SYQ8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000297785.

Proteomic databases

MaxQBiQ5SYQ8.
PaxDbiQ5SYQ8.
PeptideAtlasiQ5SYQ8.
PRIDEiQ5SYQ8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000419959; ENSP00000388026; ENSG00000165092.
UCSCiuc064ttb.1. human.

Organism-specific databases

HGNCiHGNC:402. ALDH1A1.
OpenTargetsiENSG00000165092.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2450. Eukaryota.
COG1012. LUCA.
GeneTreeiENSGT00760000118999.
HOGENOMiHOG000271516.
HOVERGENiHBG000097.

Miscellaneous databases

ChiTaRSiALDH1A1. human.

Gene expression databases

BgeeiENSG00000165092.
ExpressionAtlasiQ5SYQ8. baseline and differential.

Family and domain databases

Gene3Di3.40.605.10. 1 hit.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMiSSF53720. SSF53720. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ5SYQ8_HUMAN
AccessioniPrimary (citable) accession number: Q5SYQ8
Entry historyi
Integrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: November 30, 2016
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.