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Protein
Submitted name:

Neurofibromin

Gene

Nf1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
NeurofibrominImported
Gene namesi
Name:Nf1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:97306. Nf1.

PTM / Processingi

Proteomic databases

MaxQBiQ5SYH9.
PaxDbiQ5SYH9.
PRIDEiQ5SYH9.

Expressioni

Gene expression databases

BgeeiQ5SYH9.
ExpressionAtlasiQ5SYH9. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000071289.

Family & Domainsi

Phylogenomic databases

eggNOGiKOG1826. Eukaryota.
ENOG410XRPJ. LUCA.
GeneTreeiENSGT00550000074797.
HOGENOMiHOG000070152.
HOVERGENiHBG086885.

Family and domain databases

InterProiIPR016024. ARM-type_fold.
IPR028553. Neurofibromin.
[Graphical view]
PANTHERiPTHR10194:SF90. PTHR10194:SF90. 1 hit.
SUPFAMiSSF48371. SSF48371. 4 hits.

Sequencei

Sequence statusi: Fragment.

Q5SYH9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
IKTSATGGLG SIKAEVMADT AVALASGNVK LVSSKVIGRM CKIIDKTCLS
60 70 80 90 100
PTPTLEQHLM WDDIAILARY MLMLSFNNSL DVAAHLPYLF HVVTFLVATG
110 120 130 140 150
PLSLRASTHG LLINIIHSLC TCSQLHFSEE TKQVLRLSLT EFSLPKFYLL
160 170 180 190 200
FGISKVKSAA VIAFRSSYRD RSFSPGSYER ETFALTSLET VTEALLEIME
210 220 230 240 250
ACMRDIPTCK WLDQWTELAQ RFAFQYNPSL QPRALVVFGC ISKRVSHGQI
260 270 280 290 300
KQIIRILSKA LESCLKGPDT YNSQVLIEST VIALTKLQPL LNKDSPLHKA
310 320 330 340 350
LFWVAVAVLQ LDEVNLYSAG TALLEQNLHT LDSLRIFNDK SPEEVFMAIR
360 370 380 390 400
NPLEWHCKQM DHFVGLNFNS NFNFALVGHL LKGYRHPSPA IVARTVRILH
410 420 430 440 450
TLLTLVNKHR NCDKFEVNTQ SVAYLAALLT VSEEVRSRCS LKHRKSLLLT
460 470 480 490 500
DISMENVPMD TYPIHHGDPS YRTLKETQPW SSPKGSEGYL AATYPAVGQT
510 520 530 540 550
SPRARKSMSL DMGQPSQANT KKLLGTRKSF DHLISDTKAP KRQEMESGIT
560 570 580 590 600
TPPKMRRVAE TDYEMAETQR IPSSQQHPHL RKVSVSESNV LLDEEVLTDP
610 620 630 640 650
KIQALLLTVL ATLVKYTTDE FDQRILYEYL AEASVVFPKV FPVVHNLLDS
660 670 680 690 700
KINTLLSLCQ DPNLLNPIHG IVQSVVYHEE SPPQYQTSYL QSFGFNGLWR
710 720 730 740 750
FAGPFSKQTQ IPDYAELIVK FLDALIDTYL PGIDEETSEE SLLTPTSPYP
760 770 780 790 800
PALQSQLSIT ANLNLSNSMT SLATSQHSPG LDKENVELSP TAGHCNSGRT
810 820
RHGSASQVQK QRSAGSFKRN SIKKIV
Length:826
Mass (Da):92,204
Last modified:December 21, 2004 - v1
Checksum:i11B48407EB242862
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591126 Genomic DNA. No translation available.
AL591174 Genomic DNA. No translation available.
AL672209 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000137997; ENSMUSP00000120982; ENSMUSG00000020716.
UCSCiuc007kkt.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591126 Genomic DNA. No translation available.
AL591174 Genomic DNA. No translation available.
AL672209 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000071289.

Proteomic databases

MaxQBiQ5SYH9.
PaxDbiQ5SYH9.
PRIDEiQ5SYH9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000137997; ENSMUSP00000120982; ENSMUSG00000020716.
UCSCiuc007kkt.1. mouse.

Organism-specific databases

MGIiMGI:97306. Nf1.

Phylogenomic databases

eggNOGiKOG1826. Eukaryota.
ENOG410XRPJ. LUCA.
GeneTreeiENSGT00550000074797.
HOGENOMiHOG000070152.
HOVERGENiHBG086885.

Miscellaneous databases

ChiTaRSiNf1. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiQ5SYH9.
ExpressionAtlasiQ5SYH9. baseline and differential.

Family and domain databases

InterProiIPR016024. ARM-type_fold.
IPR028553. Neurofibromin.
[Graphical view]
PANTHERiPTHR10194:SF90. PTHR10194:SF90. 1 hit.
SUPFAMiSSF48371. SSF48371. 4 hits.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ5SYH9_MOUSE
AccessioniPrimary (citable) accession number: Q5SYH9
Entry historyi
Integrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: March 16, 2016
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.