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Q5SXJ2

- NBPFG_HUMAN

UniProt

Q5SXJ2 - NBPFG_HUMAN

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Protein
Neuroblastoma breakpoint family member 16
Gene
NBPF16
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
Neuroblastoma breakpoint family member 16
Gene namesi
Name:NBPF16
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 1

Organism-specific databases

HGNCiHGNC:31996. NBPF16.

Subcellular locationi

Cytoplasm Inferred

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 670670Neuroblastoma breakpoint family member 16
PRO_0000288050Add
BLAST

Proteomic databases

PaxDbiQ5SXJ2.
PRIDEiQ5SXJ2.

Expressioni

Gene expression databases

BgeeiQ5SXJ2.
GenevestigatoriQ5SXJ2.

Interactioni

Protein-protein interaction databases

IntActiQ5SXJ2. 1 interaction.
STRINGi9606.ENSP00000254372.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini165 – 25793NBPF 1
Add
BLAST
Domaini258 – 32972NBPF 2
Add
BLAST
Domaini330 – 42192NBPF 3
Add
BLAST
Domaini424 – 47956NBPF 4
Add
BLAST
Domaini480 – 57293NBPF 5
Add
BLAST
Domaini573 – 67098NBPF 6
Add
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili70 – 13061 Reviewed prediction
Add
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi264 – 2685Poly-Glu
Compositional biasi279 – 2846Poly-Glu
Compositional biasi486 – 4894Poly-Glu

Sequence similaritiesi

Belongs to the NBPF family.
Contains 6 NBPF domains.

Keywords - Domaini

Coiled coil, Repeat

Phylogenomic databases

eggNOGiNOG116165.
HOGENOMiHOG000049041.
HOVERGENiHBG058300.
InParanoidiQ5SXJ2.
OMAiSTFEEDK.
OrthoDBiEOG7GBFWV.
PhylomeDBiQ5SXJ2.
TreeFamiTF341151.

Family and domain databases

InterProiIPR010630. NBPF_dom.
[Graphical view]
PfamiPF06758. DUF1220. 6 hits.
[Graphical view]
PROSITEiPS51316. NBPF. 6 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5SXJ2-1 [UniParc]FASTAAdd to Basket

« Hide

MVVSAGPLSS EKAEMNILEI NEKLRPQLAE KKQQFRNLKE KCFLTQLAGF    50
LANRQKKYKY EECKDLIKFM LRNERQFKEE KLAEQLKQAE ELRQYKVLVH 100
AQERELTQLR EKLREGRDAS RSLNEHLQAL LTPDEPDKSQ GQDLQEQLAE 150
GCRLTQHLVQ KLSPENDNDD DEDVQVEVAE KVQKSSAPRE MQKAEEKEVP 200
EDSLEECAIT CSNSHGPYDS NQPHKKTKIT FEEDKVDSTL IGSSSHVEWE 250
DAVHIIPENE SDDEEEEEKG PVSPRNLQES EEEEVPQESW DEGYSTLSIP 300
PEMLASYQSY SSTFHSLEEQ QVCMAVDIGR HRWDQVKKED QEATGPRLSR 350
ELLDEKEPEV LQDSLDRCYS TPSGCLELTD SCQPYRSAFY VLEQQRVGLA 400
IDMDEIEKYQ EVEEDQDPSC PRLSRELLDE KEPEVLQDSL DRCYSTPSDY 450
LELPDLGQPY SSAVYSLEEQ YLGLALDVDR IKKDQEEEED QGPPCPRLSR 500
ELLEVVEPEV LQDSLDRYYS TPSSCLEQPD SCQPYGSSFY ALEEKHVGFS 550
LDVGEIEKKG KGKKRRGRRS KKKRRRGRKE GEDDNPPCPR LNGVLMEVEE 600
PEVLQDSLDR CYSTQSMYFE LPDSFQHYRS VFYSFEEEHI SFALYVDNRF 650
FTLTVTSLHL VFQMGVIFPQ 670
Length:670
Mass (Da):77,590
Last modified:December 21, 2004 - v1
Checksum:i12368C7951CC4C28
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL592492 Genomic DNA. Translation: CAI16654.1.

Genome annotation databases

UCSCiuc009wkt.1. human.

Polymorphism databases

DMDMi74743973.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL592492 Genomic DNA. Translation: CAI16654.1 .

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q5SXJ2. 1 interaction.
STRINGi 9606.ENSP00000254372.

Polymorphism databases

DMDMi 74743973.

Proteomic databases

PaxDbi Q5SXJ2.
PRIDEi Q5SXJ2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

UCSCi uc009wkt.1. human.

Organism-specific databases

GeneCardsi GC01P148741.
HGNCi HGNC:31996. NBPF16.
MIMi 614005. gene.
neXtProti NX_Q5SXJ2.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG116165.
HOGENOMi HOG000049041.
HOVERGENi HBG058300.
InParanoidi Q5SXJ2.
OMAi STFEEDK.
OrthoDBi EOG7GBFWV.
PhylomeDBi Q5SXJ2.
TreeFami TF341151.

Miscellaneous databases

PROi Q5SXJ2.
SOURCEi Search...

Gene expression databases

Bgeei Q5SXJ2.
Genevestigatori Q5SXJ2.

Family and domain databases

InterProi IPR010630. NBPF_dom.
[Graphical view ]
Pfami PF06758. DUF1220. 6 hits.
[Graphical view ]
PROSITEi PS51316. NBPF. 6 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The DNA sequence and biological annotation of human chromosome 1."
    Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
    , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
    Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiNBPFG_HUMAN
AccessioniPrimary (citable) accession number: Q5SXJ2
Secondary accession number(s): A8MPT6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: December 21, 2004
Last modified: April 16, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Miscellaneous

Encoded by one of the numerous copies of NBPF genes clustered in the p36, p12 and q21 region of the chromosome 1.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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