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Q5SXJ2

- NBPFG_HUMAN

UniProt

Q5SXJ2 - NBPFG_HUMAN

Protein

Neuroblastoma breakpoint family member 16

Gene

NBPF16

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 68 (01 Oct 2014)
      Sequence version 1 (21 Dec 2004)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Neuroblastoma breakpoint family member 16
    Gene namesi
    Name:NBPF16
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 1

    Organism-specific databases

    HGNCiHGNC:31996. NBPF16.

    Subcellular locationi

    Cytoplasm Curated

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 670670Neuroblastoma breakpoint family member 16PRO_0000288050Add
    BLAST

    Proteomic databases

    PaxDbiQ5SXJ2.
    PRIDEiQ5SXJ2.

    Expressioni

    Gene expression databases

    BgeeiQ5SXJ2.
    GenevestigatoriQ5SXJ2.

    Interactioni

    Protein-protein interaction databases

    IntActiQ5SXJ2. 1 interaction.
    STRINGi9606.ENSP00000254372.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini165 – 25793NBPF 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini258 – 32972NBPF 2PROSITE-ProRule annotationAdd
    BLAST
    Domaini330 – 42192NBPF 3PROSITE-ProRule annotationAdd
    BLAST
    Domaini424 – 47956NBPF 4PROSITE-ProRule annotationAdd
    BLAST
    Domaini480 – 57293NBPF 5PROSITE-ProRule annotationAdd
    BLAST
    Domaini573 – 67098NBPF 6PROSITE-ProRule annotationAdd
    BLAST

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili70 – 13061Sequence AnalysisAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi264 – 2685Poly-Glu
    Compositional biasi279 – 2846Poly-Glu
    Compositional biasi486 – 4894Poly-Glu

    Sequence similaritiesi

    Belongs to the NBPF family.Curated
    Contains 6 NBPF domains.PROSITE-ProRule annotation

    Keywords - Domaini

    Coiled coil, Repeat

    Phylogenomic databases

    eggNOGiNOG116165.
    HOGENOMiHOG000049041.
    HOVERGENiHBG058300.
    InParanoidiQ5SXJ2.
    OMAiSTFEEDK.
    OrthoDBiEOG7GBFWV.
    PhylomeDBiQ5SXJ2.
    TreeFamiTF341151.

    Family and domain databases

    InterProiIPR010630. NBPF_dom.
    [Graphical view]
    PfamiPF06758. DUF1220. 6 hits.
    [Graphical view]
    PROSITEiPS51316. NBPF. 6 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5SXJ2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVVSAGPLSS EKAEMNILEI NEKLRPQLAE KKQQFRNLKE KCFLTQLAGF    50
    LANRQKKYKY EECKDLIKFM LRNERQFKEE KLAEQLKQAE ELRQYKVLVH 100
    AQERELTQLR EKLREGRDAS RSLNEHLQAL LTPDEPDKSQ GQDLQEQLAE 150
    GCRLTQHLVQ KLSPENDNDD DEDVQVEVAE KVQKSSAPRE MQKAEEKEVP 200
    EDSLEECAIT CSNSHGPYDS NQPHKKTKIT FEEDKVDSTL IGSSSHVEWE 250
    DAVHIIPENE SDDEEEEEKG PVSPRNLQES EEEEVPQESW DEGYSTLSIP 300
    PEMLASYQSY SSTFHSLEEQ QVCMAVDIGR HRWDQVKKED QEATGPRLSR 350
    ELLDEKEPEV LQDSLDRCYS TPSGCLELTD SCQPYRSAFY VLEQQRVGLA 400
    IDMDEIEKYQ EVEEDQDPSC PRLSRELLDE KEPEVLQDSL DRCYSTPSDY 450
    LELPDLGQPY SSAVYSLEEQ YLGLALDVDR IKKDQEEEED QGPPCPRLSR 500
    ELLEVVEPEV LQDSLDRYYS TPSSCLEQPD SCQPYGSSFY ALEEKHVGFS 550
    LDVGEIEKKG KGKKRRGRRS KKKRRRGRKE GEDDNPPCPR LNGVLMEVEE 600
    PEVLQDSLDR CYSTQSMYFE LPDSFQHYRS VFYSFEEEHI SFALYVDNRF 650
    FTLTVTSLHL VFQMGVIFPQ 670
    Length:670
    Mass (Da):77,590
    Last modified:December 21, 2004 - v1
    Checksum:i12368C7951CC4C28
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL592492 Genomic DNA. Translation: CAI16654.1.

    Genome annotation databases

    UCSCiuc009wkt.1. human.

    Polymorphism databases

    DMDMi74743973.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL592492 Genomic DNA. Translation: CAI16654.1 .

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi Q5SXJ2. 1 interaction.
    STRINGi 9606.ENSP00000254372.

    Polymorphism databases

    DMDMi 74743973.

    Proteomic databases

    PaxDbi Q5SXJ2.
    PRIDEi Q5SXJ2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    UCSCi uc009wkt.1. human.

    Organism-specific databases

    GeneCardsi GC01P148741.
    HGNCi HGNC:31996. NBPF16.
    MIMi 614005. gene.
    neXtProti NX_Q5SXJ2.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG116165.
    HOGENOMi HOG000049041.
    HOVERGENi HBG058300.
    InParanoidi Q5SXJ2.
    OMAi STFEEDK.
    OrthoDBi EOG7GBFWV.
    PhylomeDBi Q5SXJ2.
    TreeFami TF341151.

    Miscellaneous databases

    PROi Q5SXJ2.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q5SXJ2.
    Genevestigatori Q5SXJ2.

    Family and domain databases

    InterProi IPR010630. NBPF_dom.
    [Graphical view ]
    Pfami PF06758. DUF1220. 6 hits.
    [Graphical view ]
    PROSITEi PS51316. NBPF. 6 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
      , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
      Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiNBPFG_HUMAN
    AccessioniPrimary (citable) accession number: Q5SXJ2
    Secondary accession number(s): A8MPT6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 29, 2007
    Last sequence update: December 21, 2004
    Last modified: October 1, 2014
    This is version 68 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Miscellaneous

    Encoded by one of the numerous copies of NBPF genes clustered in the p36, p12 and q21 region of the chromosome 1.

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 1
      Human chromosome 1: entries, gene names and cross-references to MIM
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3