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Protein
Submitted name:

Vascular endothelial zinc finger 1

Gene

Vezf1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • angiogenesis Source: MGI
  • endothelial cell development Source: MGI
  • positive regulation of transcription from RNA polymerase II promoter Source: MGI

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Vascular endothelial zinc finger 1Imported
Gene namesi
Name:Vezf1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:1313291. Vezf1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiQ5SXC4.
PaxDbiQ5SXC4.
PeptideAtlasiQ5SXC4.

PTM databases

iPTMnetiQ5SXC4.
PhosphoSitePlusiQ5SXC4.

Expressioni

Gene expression databases

BgeeiENSMUSG00000018377.
ExpressionAtlasiQ5SXC4. baseline and differential.
GenevisibleiQ5SXC4. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000018521.

Structurei

3D structure databases

ProteinModelPortaliQ5SXC4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini74 – 101C2H2-typeInterPro annotationAdd BLAST28
Domaini174 – 201C2H2-typeInterPro annotationAdd BLAST28
Domaini202 – 226C2H2-typeInterPro annotationAdd BLAST25
Domaini232 – 260C2H2-typeInterPro annotationAdd BLAST29
Domaini261 – 288C2H2-typeInterPro annotationAdd BLAST28

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00530000063522.
HOGENOMiHOG000294183.
HOVERGENiHBG058083.
InParanoidiQ5SXC4.
OMAiKQGINKT.
OrthoDBiEOG091G06L9.
PhylomeDBiQ5SXC4.
TreeFamiTF331686.

Family and domain databases

InterProiView protein in InterPro
IPR036236. Znf_C2H2_sf.
IPR013087. Znf_C2H2_type.
SMARTiView protein in SMART
SM00355. ZnF_C2H2. 6 hits.
SUPFAMiSSF57667. SSF57667. 3 hits.
PROSITEiView protein in PROSITE
PS00028. ZINC_FINGER_C2H2_1. 5 hits.
PS50157. ZINC_FINGER_C2H2_2. 5 hits.

Sequencei

Sequence statusi: Complete.

Q5SXC4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEANWTAFLF QAHEASHHQQ QAAQNSLLPL LSSAVEPPDQ KPLLPIPITQ
60 70 80 90 100
KPQAAPETLK DAIGIKKEKP KTSFVCTYCS KAFRDSYHLR RHQSCHTGIK
110 120 130 140 150
LVSRAKKTPT TVVPLISTIA GDSSRTSLVS TIAGILSTVT TSSSGTNPSS
160 170 180 190 200
SASTTSMPVP QSVKKPSKPV KKNHACEMCG KAFRDVYHLN RHKLSHSDEK
210 220 230 240 250
PFECPICNQR FKRKDRMTYH VRSHEGGITK PYTCSVCGKG FSRPDHLSCH
260 270 280 290 300
VKHVHSTERP FKCQTCTAAF ATKDRLRTHM VRHEGKVSCN ICGKLLSAAY
310 320 330 340 350
ITSHLKTHGQ SQSINCNTCK QGISKTCMSE ETSNQKQQQQ QQQQQQQQQQ
360 370 380 390 400
QHVTSWPGKQ VETLRLWEEA VKARKKEAAN LCQTSTAATT PVTLTTPFNI
410 420 430 440 450
TSSVSSGTMS NPVTVAAAMS MRSPVNVSSA VNITSPMNIG HPVTITSPLA
460 470 480 490 500
MTSPLTLTTP VNLPTPVTAP VNIAHPVTIT SPMNLPTPMT LAAPLNIAMR
510
PVESMPFLPQ ALPTSPPW
Length:518
Mass (Da):56,557
Last modified:December 21, 2004 - v1
Checksum:i26E09F405088D937
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL593853 Genomic DNA. No translation available.
RefSeqiNP_057895.2. NM_016686.4.
UniGeneiMm.46628.

Genome annotation databases

EnsembliENSMUST00000018521; ENSMUSP00000018521; ENSMUSG00000018377.
GeneIDi22344.
KEGGimmu:22344.
UCSCiuc007kvf.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ5SXC4_MOUSE
AccessioniPrimary (citable) accession number: Q5SXC4
Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: November 22, 2017
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported