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Protein
Submitted name:

Vascular endothelial zinc finger 1

Gene

Vezf1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • angiogenesis Source: MGI
  • endothelial cell development Source: MGI
  • positive regulation of endothelial cell differentiation Source: Ensembl
  • positive regulation of transcription by RNA polymerase II Source: MGI

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Vascular endothelial zinc finger 1Imported
Gene namesi
Name:Vezf1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:1313291 Vezf1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiQ5SXC4
PaxDbiQ5SXC4
PeptideAtlasiQ5SXC4

PTM databases

iPTMnetiQ5SXC4
PhosphoSitePlusiQ5SXC4

Expressioni

Gene expression databases

BgeeiENSMUSG00000018377
ExpressionAtlasiQ5SXC4 baseline and differential
GenevisibleiQ5SXC4 MM

Interactioni

Protein-protein interaction databases

CORUMiQ5SXC4
STRINGi10090.ENSMUSP00000018521

Structurei

3D structure databases

ProteinModelPortaliQ5SXC4
SMRiQ5SXC4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini74 – 101C2H2-typeInterPro annotationAdd BLAST28
Domaini174 – 201C2H2-typeInterPro annotationAdd BLAST28
Domaini202 – 226C2H2-typeInterPro annotationAdd BLAST25
Domaini232 – 260C2H2-typeInterPro annotationAdd BLAST29
Domaini261 – 288C2H2-typeInterPro annotationAdd BLAST28

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili329 – 349Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00530000063522
HOGENOMiHOG000294183
HOVERGENiHBG058083
InParanoidiQ5SXC4
OMAiKQGINKT
OrthoDBiEOG091G06L9
PhylomeDBiQ5SXC4
TreeFamiTF331686

Family and domain databases

InterProiView protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 6 hits
SUPFAMiSSF57667 SSF57667, 3 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 5 hits
PS50157 ZINC_FINGER_C2H2_2, 5 hits

Sequencei

Sequence statusi: Complete.

Q5SXC4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEANWTAFLF QAHEASHHQQ QAAQNSLLPL LSSAVEPPDQ KPLLPIPITQ
60 70 80 90 100
KPQAAPETLK DAIGIKKEKP KTSFVCTYCS KAFRDSYHLR RHQSCHTGIK
110 120 130 140 150
LVSRAKKTPT TVVPLISTIA GDSSRTSLVS TIAGILSTVT TSSSGTNPSS
160 170 180 190 200
SASTTSMPVP QSVKKPSKPV KKNHACEMCG KAFRDVYHLN RHKLSHSDEK
210 220 230 240 250
PFECPICNQR FKRKDRMTYH VRSHEGGITK PYTCSVCGKG FSRPDHLSCH
260 270 280 290 300
VKHVHSTERP FKCQTCTAAF ATKDRLRTHM VRHEGKVSCN ICGKLLSAAY
310 320 330 340 350
ITSHLKTHGQ SQSINCNTCK QGISKTCMSE ETSNQKQQQQ QQQQQQQQQQ
360 370 380 390 400
QHVTSWPGKQ VETLRLWEEA VKARKKEAAN LCQTSTAATT PVTLTTPFNI
410 420 430 440 450
TSSVSSGTMS NPVTVAAAMS MRSPVNVSSA VNITSPMNIG HPVTITSPLA
460 470 480 490 500
MTSPLTLTTP VNLPTPVTAP VNIAHPVTIT SPMNLPTPMT LAAPLNIAMR
510
PVESMPFLPQ ALPTSPPW
Length:518
Mass (Da):56,557
Last modified:December 21, 2004 - v1
Checksum:i26E09F405088D937
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL593853 Genomic DNA No translation available.
RefSeqiNP_057895.2, NM_016686.4
UniGeneiMm.46628

Genome annotation databases

EnsembliENSMUST00000018521; ENSMUSP00000018521; ENSMUSG00000018377
GeneIDi22344
KEGGimmu:22344
UCSCiuc007kvf.2 mouse

Similar proteinsi

Entry informationi

Entry nameiQ5SXC4_MOUSE
AccessioniPrimary (citable) accession number: Q5SXC4
Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: April 25, 2018
This is version 116 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health