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Protein

Profilin

Gene

Pfn1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

Actin-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
ProfilinUniRule annotation
Gene namesi
Name:Pfn1Imported
ORF Names:mCG_21163Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:97549. Pfn1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

TopDownProteomicsiQ5SX50.

Expressioni

Gene expression databases

BgeeiENSMUSG00000018293.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000018437.

Family & Domainsi

Sequence similaritiesi

Belongs to the profilin family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1755. Eukaryota.
ENOG41126PD. LUCA.
GeneTreeiENSGT00390000010143.
HOVERGENiHBG053683.
KOiK05759.
OMAiHLRRAQY.
OrthoDBiEOG091G0TWH.

Family and domain databases

InterProiIPR005455. PFN.
IPR005454. Profilin1/2/3_vertebrate.
IPR027310. Profilin_CS.
[Graphical view]
PfamiPF00235. Profilin. 1 hit.
[Graphical view]
PRINTSiPR01639. PROFILINMAML.
SMARTiSM00392. PROF. 1 hit.
[Graphical view]
SUPFAMiSSF55770. SSF55770. 1 hit.
PROSITEiPS00414. PROFILIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5SX50-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGWNAYIDS LMADGTCQDA AIVGYKDSPS VWAAVPGKTF VSITPAEVGV
60 70 80 90 100
LVGKDRSSFF VNGLTLGGQK CSVIRDSLLQ DGEFTMDLRT KSTGGAPTFN
110 120 130 140
VTVTMTAKTL VLLMGKEGVH GGLINKKCYE MASHLRRSQY
Length:140
Mass (Da):14,957
Last modified:May 10, 2005 - v1
Checksum:i1DC8B60D545FF70E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK150780 mRNA. Translation: BAE29845.1.
AK160191 mRNA. Translation: BAE35684.1.
CH466596 Genomic DNA. Translation: EDL12597.1.
RefSeqiNP_035202.1. NM_011072.4.
UniGeneiMm.2647.

Genome annotation databases

GeneIDi18643.
KEGGimmu:18643.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK150780 mRNA. Translation: BAE29845.1.
AK160191 mRNA. Translation: BAE35684.1.
CH466596 Genomic DNA. Translation: EDL12597.1.
RefSeqiNP_035202.1. NM_011072.4.
UniGeneiMm.2647.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000018437.

Proteomic databases

TopDownProteomicsiQ5SX50.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi18643.
KEGGimmu:18643.

Organism-specific databases

CTDi5216.
MGIiMGI:97549. Pfn1.

Phylogenomic databases

eggNOGiKOG1755. Eukaryota.
ENOG41126PD. LUCA.
GeneTreeiENSGT00390000010143.
HOVERGENiHBG053683.
KOiK05759.
OMAiHLRRAQY.
OrthoDBiEOG091G0TWH.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000018293.

Family and domain databases

InterProiIPR005455. PFN.
IPR005454. Profilin1/2/3_vertebrate.
IPR027310. Profilin_CS.
[Graphical view]
PfamiPF00235. Profilin. 1 hit.
[Graphical view]
PRINTSiPR01639. PROFILINMAML.
SMARTiSM00392. PROF. 1 hit.
[Graphical view]
SUPFAMiSSF55770. SSF55770. 1 hit.
PROSITEiPS00414. PROFILIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5SX50_MOUSE
AccessioniPrimary (citable) accession number: Q5SX50
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: September 7, 2016
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.