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Q5SWT9 (Q5SWT9_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
DNA-binding protein Ikaros Ensembl ENSMUSP00000067372
Gene names
Name:Ikzf1 Ensembl ENSMUSP00000067372 MGI 1342540
OrganismMus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000067372
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length535 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000067372

Ontologies

Keywords
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processB cell differentiation

Inferred from mutant phenotype PubMed 7923373. Source: MGI

Peyer's patch development

Inferred from mutant phenotype PubMed 7923373. Source: MGI

T cell differentiation

Inferred from mutant phenotype PubMed 7923373. Source: MGI

forebrain development

Inferred from mutant phenotype PubMed 15841184PubMed 16467156. Source: MGI

gland development

Inferred from mutant phenotype PubMed 16467156. Source: MGI

lymph node development

Inferred from mutant phenotype PubMed 7923373. Source: MGI

natural killer cell differentiation

Inferred from mutant phenotype PubMed 7923373. Source: MGI

negative regulation of transcription from RNA polymerase II promoter

Inferred from direct assay PubMed 12617992. Source: MGI

positive regulation of NK T cell differentiation

Inferred from mutant phenotype PubMed 10366784. Source: MGI

positive regulation of multicellular organism growth

Inferred from mutant phenotype PubMed 16467156. Source: MGI

positive regulation of neutrophil differentiation

Inferred from mutant phenotype PubMed 12406904. Source: MGI

positive regulation of transcription from RNA polymerase II promoter

Inferred from direct assay PubMed 15841184PubMed 16467156. Source: MGI

retina development in camera-type eye

Inferred from mutant phenotype PubMed 18940586. Source: MGI

thymus development

Inferred from mutant phenotype PubMed 7923373. Source: MGI

   Cellular_componentcentromeric heterochromatin

Inferred from direct assay PubMed 15767674. Source: MGI

transcription factor complex

Traceable author statement PubMed 11805317. Source: MGI

   Molecular_functionsequence-specific DNA binding

Inferred from mutant phenotype PubMed 7923373. Source: MGI

sequence-specific DNA binding transcription factor activity

Inferred from direct assay PubMed 7969165. Source: MGI

zinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q5SWT9 [UniParc].

Last modified December 21, 2004. Version 1.
Checksum: CE37432CB83C1947

FASTA53559,408
        10         20         30         40         50         60 
MDVDEGQDMS QVSGKESPPV SDTPDEGDEP MPVPEDLSTT SGAQQNSKSD RGMVAYGADG 

        70         80         90        100        110        120 
FRDFHAIIPK SFSPSNVKVE TQSDEENGRA CEMNGEECAE DLRMLDASGE KMNGSHRDQG 

       130        140        150        160        170        180 
SSALSGVGGI RLPNGKLKCD ICGIVCIGPN VLMVHKRSHT GERPFQCNQC GASFTQKGNL 

       190        200        210        220        230        240 
LRHIKLHSGE KPFKCHLCNY ACRRRDALTG HLRTHSVGKP HKCGYCGRSY KQRSSLEEHK 

       250        260        270        280        290        300 
ERCHNYLESM GLPGMYPVIK EETNHNEMAE DLCKIGAERS LVLDRLASNV AKRKSSMPQK 

       310        320        330        340        350        360 
FLGDKCLSDM PYDSANYEKE DMMTSHVMDQ AINNAINYLG AESLRPLVQT PPGSSEVVPV 

       370        380        390        400        410        420 
ISSMYQLHKP PSDGPPRSNH SAQDAVDNLL LLSKAKSVSS EREASPSNSC QDSTDTESNA 

       430        440        450        460        470        480 
EEQRSGLIYL TNHINPHARN GLALKEEQRA YEVLRAASEN SQDAFRVVST SGEQLKVYKC 

       490        500        510        520        530 
EHCRVLFLDH VMYTIHMGCH GFRDPFECNM CGYHSQDRYE FSSHITRGEH RYHLS

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL596450 Genomic DNA. No translation available.
IPIIPI00515592.
UniGeneMm.103545.

3D structure databases

ProteinModelPortalQ5SWT9.
SMRQ5SWT9. Positions 138-240, 441-530.
ModBaseSearch...

Proteomic databases

PRIDEQ5SWT9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000065433; ENSMUSP00000067372; ENSMUSG00000018654.

Organism-specific databases

MGIMGI:1342540. Ikzf1.

Phylogenomic databases

GeneTreeENSGT00550000074392.
HOGENOMHOG000049114.
HOVERGENHBG004752.
OMAGDKCLSD.

Gene expression databases

ArrayExpressQ5SWT9.

Family and domain databases

Gene3D3.30.160.60. 4 hits.
InterProIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
SMARTSM00355. ZnF_C2H2. 6 hits.
[Graphical view]
PROSITEPS00028. ZINC_FINGER_C2H2_1. 5 hits.
PS50157. ZINC_FINGER_C2H2_2. 4 hits.
[Graphical view]
ProtoNetSearch...

Other

SOURCESearch...

Entry information

Entry nameQ5SWT9_MOUSE
AccessionPrimary (citable) accession number: Q5SWT9
Entry history
Integrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: May 1, 2013
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info