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Q5SWT9

- Q5SWT9_MOUSE

UniProt

Q5SWT9 - Q5SWT9_MOUSE

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Protein
Submitted name:

DNA-binding protein Ikaros

Gene
Ikzf1
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. DNA binding Source: MGI
  2. metal ion binding Source: InterPro
  3. protein binding Source: MGI
  4. protein heterodimerization activity Source: MGI
  5. sequence-specific DNA binding Source: MGI
  6. sequence-specific DNA binding transcription factor activity Source: MGI

GO - Biological processi

  1. B cell differentiation Source: MGI
  2. forebrain development Source: MGI
  3. gland development Source: MGI
  4. hemopoiesis Source: MGI
  5. lymph node development Source: MGI
  6. natural killer cell differentiation Source: MGI
  7. negative regulation of transcription, DNA-templated Source: MGI
  8. negative regulation of transcription from RNA polymerase II promoter Source: MGI
  9. Peyer's patch development Source: MGI
  10. positive regulation of multicellular organism growth Source: MGI
  11. positive regulation of neutrophil differentiation Source: MGI
  12. positive regulation of NK T cell differentiation Source: MGI
  13. positive regulation of transcription, DNA-templated Source: MGI
  14. positive regulation of transcription from RNA polymerase II promoter Source: MGI
  15. regulation of transcription, DNA-templated Source: MGI
  16. retina development in camera-type eye Source: MGI
  17. T cell differentiation Source: MGI
  18. thymus development Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
DNA-binding protein IkarosImported
Gene namesi
Name:Ikzf1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 11

Organism-specific databases

MGIiMGI:1342540. Ikzf1.

Subcellular locationi

GO - Cellular componenti

  1. centromeric heterochromatin Source: MGI
  2. nucleus Source: MGI
  3. transcription factor complex Source: MGI
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ5SWT9.

Structurei

3D structure databases

ProteinModelPortaliQ5SWT9.
SMRiQ5SWT9. Positions 109-240, 440-509.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00550000074392.
HOGENOMiHOG000049114.
HOVERGENiHBG004752.
OMAiGDKCLSD.

Family and domain databases

Gene3Di3.30.160.60. 4 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 6 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 5 hits.
PS50157. ZINC_FINGER_C2H2_2. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5SWT9-1 [UniParc]FASTAAdd to Basket

« Hide

MDVDEGQDMS QVSGKESPPV SDTPDEGDEP MPVPEDLSTT SGAQQNSKSD    50
RGMVAYGADG FRDFHAIIPK SFSPSNVKVE TQSDEENGRA CEMNGEECAE 100
DLRMLDASGE KMNGSHRDQG SSALSGVGGI RLPNGKLKCD ICGIVCIGPN 150
VLMVHKRSHT GERPFQCNQC GASFTQKGNL LRHIKLHSGE KPFKCHLCNY 200
ACRRRDALTG HLRTHSVGKP HKCGYCGRSY KQRSSLEEHK ERCHNYLESM 250
GLPGMYPVIK EETNHNEMAE DLCKIGAERS LVLDRLASNV AKRKSSMPQK 300
FLGDKCLSDM PYDSANYEKE DMMTSHVMDQ AINNAINYLG AESLRPLVQT 350
PPGSSEVVPV ISSMYQLHKP PSDGPPRSNH SAQDAVDNLL LLSKAKSVSS 400
EREASPSNSC QDSTDTESNA EEQRSGLIYL TNHINPHARN GLALKEEQRA 450
YEVLRAASEN SQDAFRVVST SGEQLKVYKC EHCRVLFLDH VMYTIHMGCH 500
GFRDPFECNM CGYHSQDRYE FSSHITRGEH RYHLS 535
Length:535
Mass (Da):59,408
Last modified:December 21, 2004 - v1
Checksum:iCE37432CB83C1947
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL596450 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000065433; ENSMUSP00000067372; ENSMUSG00000018654.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL596450 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali Q5SWT9.
SMRi Q5SWT9. Positions 109-240, 440-509.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q5SWT9.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000065433 ; ENSMUSP00000067372 ; ENSMUSG00000018654 .

Organism-specific databases

MGIi MGI:1342540. Ikzf1.

Phylogenomic databases

GeneTreei ENSGT00550000074392.
HOGENOMi HOG000049114.
HOVERGENi HBG004752.
OMAi GDKCLSD.

Miscellaneous databases

SOURCEi Search...

Family and domain databases

Gene3Di 3.30.160.60. 4 hits.
InterProi IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view ]
SMARTi SM00355. ZnF_C2H2. 6 hits.
[Graphical view ]
PROSITEi PS00028. ZINC_FINGER_C2H2_1. 5 hits.
PS50157. ZINC_FINGER_C2H2_2. 4 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ5SWT9_MOUSE
AccessioniPrimary (citable) accession number: Q5SWT9
Entry historyi
Integrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: June 11, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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